I. B. Goryunova

N-(1,5-dimethyl-3-oxo-2-phenyl-1,2-dihydropyrazol-4-yl)-P,P-diphenylamidophosphinate and its complexes with neodymium(III), erbium(III), thorium(IV), and uranyl nitrates: Synthesis and crystal and molecular structure

A new phosphoryl-containing ligand based on 4-aminoantipyrine-N-(1,5-dimethyl-3-oxo-2-phenyl-1,2-dihydropyrazol-4-yl)-P,P-diphenylamidophosphinate (L) was synthesized. In crystals, the L molecules were found to be combined in centrosymmetric dimers through N-H…O=C hydrogen bonds. The complexes of L with neodymium(III), erbium(III), thorium(IV), and uranyl nitrates were obtained, and their structures were determined. The bands of the C=O and P=O groups in the IR spectra of these complexes are shifted toward low frequencies (by 50–65 and 40–70 cm−1, respectively), which is indicative of a bidentate coordination of the organophosphorus ligand. According to the X-ray crystallography data, uranyl is bidentately coordinated by both the L molecule (through the C=O and P=O groups) and two nitrate anions.

Bis(pentafluorophenyl)phosphinous acid in the synthesis of P,P-bis(pentafluorophenyl)phosphorylalkanones and -alkanediones

Addition of bis(pentafluorophenyl)phosphinous acid to α,β-alkenones and α,β,β’-alkene-diones in anhydrous Et2O (the solvent, in which the P-OH tautomeric form predominates) proceeds rapidly and regiospecifically at the C=C bond of the substrate at room temperature in the absence of catalysts. The reaction leads to bis(pentafluorophenyl)phosphorylated alkanones and alkanediones, as a rule, in the yields close to quantitative and can be considered as a highly efficient method for the synthesis of the corresponding functionalized phosphine oxides. The structures of obtained compounds were established by IR and NMR spectroscopy and X-ray diffraction analysis.

Phosphorylation of cytisine using azide—alkyne click chemistry

Abstract4-Cytisine-substituted 1-phosphorylated 1,2,3-triazoles possessing potential biological activity were first synthesized by the click reaction of N-propargyl cytisine with azido-γ-alkyl phosphates and phosphonates.

Synthesis and extraction properties of first representatives of 2-(phosphorylamido)-substituted 1,8-naphthyridines

ISSN 0012-5008, Doklady Chemistry, 2009, Vol. 425, Part 2, pp. 84–87.

Catalytic synthesis of O-aryl methyl(phenyl)phosphonochloridates

The reaction of methyl- and phenyldichlorophosphonates with phenols in the presence of anhydrous magnesium chloride (catalyst) or magnesium metal (procatalyst) has been used as a simple, efficient, and industrially feasible method for the synthesis of the corresponding O-aryl alkyl(aryl)phosphonochloridates.

(2-carbamoylethyl)bis(pentafluorophenyl)phosphine oxides: Synthesis and structure

The interaction of a series of acrylic and cinnamic acid amides with bis(pentafluorophenyl)-phosphinic acid proceeds vigorously at room temperature without any catalyst in the presence of the organic solvents providing for a high fraction of the >P–OH tautomer of the phosphinic acid. The reactions have afforded (2-carbamoylethyl)bis(pentafluorophenyl)phosphine oxides in a high yield.

Diarylphosphoryl-containing β-Diketones: Methods of synthesis and transformation into pyrazoles

35 Functionalized phosphine oxides containing oxoalkyl substituents where phosphoryl and carbonyl groups are separated by the ethylene fragment have attracted much recent attention. For example, 4 (diorganylphosphoryl) 4 methylpentan 2 ones (I) can be used as fire retardants for poly(vinyl chloride), the best results having been obtained for diarylphos phoryl compounds [1]. Later, phosphorylmonoke tones of type I have been demonstrated to be efficient extractants of lanthanides from acid solutions, better than such a known bidentate organophosphorus extractant as N,N dibutylcarbamoylmethylphosphine oxide Ph2P(O)CH2C(O)N(Bu n)2 [2].