Ian C. Jones

Lateral trunk lean explains variation in dynamic knee joint load in patients with medial compartment knee osteoarthritis

OBJECTIVE To test the hypothesis that selected gait kinematics, particularly lateral trunk lean, observed in patients with medial compartment knee osteoarthritis explain variation in dynamic knee joint load. METHOD In this cross-sectional observational study, 120 patients with radiographically confirmed varus gonarthrosis underwent three-dimensional gait analysis at their typical walking speed. We used sequential (hierarchical) linear regression to examine the amount of variance in dynamic knee joint load (external knee adduction moment) explained by static lower limb alignment (mechanical axis angle) and gait kinematics determined a priori based on their proposed effect on knee load (walking speed, toe-out angle, and lateral trunk lean angle). RESULTS Approximately 50% of the variation in the first peak external knee adduction moment was explained by mechanical axis angle (25%), Western Ontario and McMaster Universities Osteoarthritis Index pain score (1%), gait speed (1%), toe-out angle (12%), and lateral trunk lean angle (13%). There was no confounding or interaction with Kellgren and Lawrence grade of severity. CONCLUSIONS Gait kinematics, particularly lateral trunk lean, explain substantial variation in dynamic knee joint load in patients with medial compartment knee osteoarthritis. While largely ignored in previous gait studies, the effect of lateral trunk lean should be considered in future research evaluating risk factors and interventions for progression of knee osteoarthritis.

Radiographic Measures of Knee Alignment in Patients With Varus Gonarthrosis Effect of Weightbearing Status and Associations With Dynamic Joint Load

Background Radiographic measures of lower limb malalignment are used to indicate abnormal loading of the knee and to plan corrective procedures. Hypotheses Weightbearing status during hip-to-ankle radiographs will significantly affect malalignment measures; malalignment in single-limb standing will be most highly correlated to the external knee adduction moment during gait, a proposed dynamic measure of functional knee joint load. Study Design Controlled laboratory study. Methods Mechanical axis angle was measured in 40 patients with varus gonarthrosis from hip-to-ankle radiographs taken with patients in single-limb standing, double-limb standing, and supine positions. Kinematic and kinetic data were collected during walking and used to calculate the peak adduction moment about the knee. Results Repeated-measures analysis of variance and Scheffé post hoc tests indicated that mechanical axis angle measured on single-limb standing radiographs (-8.7°± 4.0°) was significantly greater than on double-limb standing radiographs (-7.1°± 3.8°), which was significantly greater than on supine radiographs (-5.5°± 2.8°). The peak knee adduction moment (2.8 ± 0.8 percentage body weight × height) was only moderately correlated with mechanical axis angle on single-limb standing (r = -0.46), double-limb standing (r = -0.45), and supine (r = -0.43) radiographs. Conclusion Patient position significantly affects frontal plane knee alignment. However, the peak knee adduction moment is only moderately correlated to mechanical axis angle, regardless of weightbearing status. Clinical Relevance These findings are inconsistent with the hypothesis that mechanical axis angle measured in single-limb standing is more representative of dynamic joint load and further highlight the differences between static and dynamic measures. Results also underscore the importance of reporting patient position during radiographs and keeping positions consistent when evaluating patients over time.

Resistance training for medial compartment knee osteoarthritis and malalignment.

PURPOSES 1) To evaluate the effects of a 12-wk high-intensity knee extensor and flexor resistance training program on strength, pain, and adherence in patients with advanced knee osteoarthritis and varus malalignment and 2) to generate pilot data for change in dynamic knee joint load, patent-reported outcomes, and self-efficacy after training. METHODS Fourteen patients (48.35 +/- 6.51 yr) with radiographically confirmed medial compartment knee osteoarthritis and varus malalignment of the lower limb were recruited from a surgical waiting list for high tibial osteotomy. Participants completed a high-intensity isokinetic resistance training program three times per week for 12 wk. Knee extensor and flexor strength were assessed every third week, whereas pain and adherence were recorded at every training session. The external knee adduction moment during the gait, the 6-min-walk test, the Knee Injury and Osteoarthritis Outcome Score (KOOS), and the Arthritis Self-Efficacy Scale (ASES) were also evaluated before and after training. RESULTS Significant improvements in knee extensor and flexor strength were observed without increases in pain during or after training. Adherence to the high-intensity program was high. No significant changes were observed for dynamic knee joint load or the KOOS. There was a significant increase in the function subscale of the ASES only. CONCLUSIONS These findings suggest that patients with advanced knee osteoarthritis and malalignment can experience substantial gains in strength after a high-intensity resistance training program without concomitant increases in pain, adverse events, or compromised adherence. These findings provide support for future clinical trials with longer-term outcomes.

Electromyography and Kinematics of the Trunk during Rowing in Elite Female Rowers

PURPOSE The purpose of this study was to characterize the EMG of trunk muscles together with kinematics of the pelvis and the spine of elite female rowers during the rowing stroke. METHODS Nine Rowing Canada national team candidates performed a 2000-m race simulation. EMG activity of spinal and pelvic extensor and flexor muscles and kinematic data of the pelvis and the spine were collected and analyzed during the period of peak force production. RESULTS During this period, pelvic and spinal extensor muscles demonstrated similarities in the timing of muscle activity with minimal coactivation of flexors and extensors. Minimal excursion of spinal segments occurred during the stroke with most of the extension occurring at the pelvis. Flexor activity occurred toward late drive, suggesting that trunk extension is slowed by increasing activity of the flexor muscles. CONCLUSIONS This study provides data of trunk kinematics and muscle recruitment patterns in elite female rowers. During the period of peak force production, there is minimal coactivation of trunk flexor and extensor muscles and, of the spinal segments, L3-S1 shows the most movement, which may make it more susceptible to soft tissue injury.

Moments and Muscle Activity after High Tibial Osteotomy and Anterior Cruciate Ligament Reconstruction

PURPOSES To evaluate the effects of simultaneous high tibial osteotomy (HTO) and anterior cruciate ligament (ACL) reconstruction on 1) the external knee adduction moment, 2) the external knee flexion and extension moments, and 3) the quadriceps, hamstrings, and gastrocnemius muscle activity during walking. METHODS Twenty-one patients with varus malalignment of the lower limb, medial compartment knee osteoarthritis, and concomitant anterior cruciate ligament (ACL) deficiency were tested before and 1 yr after undergoing simultaneous medial opening wedge high tibial osteotomy (HTO) and ACL reconstruction during a single operation. Three-dimensional kinetic and kinematic data were used to calculate external coronal and sagittal moments about the knee. EMG data from the quadriceps, hamstrings, and gastrocnemius were used to determine coactivation ratio and activation patterns. RESULTS Neutral alignment and knee stability were achieved in all patients after surgery. The peak knee adduction moment decreased from 2.88 +/- 0.57 to 1.71 +/- 0.56%BW x Ht (P < 0.001). The early stance knee flexion moment decreased from 1.95 +/- 1.89 to 0.88 +/- 1.17%BW x Ht (P < 0.01). The late stance knee extension moment increased from 1.83 +/- 1.53 to 2.76 +/- 1.22%BW x Ht (P < 0.001). There were no significant differences in muscle coactivation or muscle activation patterns (P > 0.05). CONCLUSIONS Improving lower limb alignment and knee stability significantly alters the coronal and the sagittal moments about the knee during walking, without apparent changes in muscle activation patterns.

Changes in kinematics and trunk electromyography during a 2000 m race simulation in elite female rowers.

Achieving excellence in rowing requires optimization of technique to maximize efficiency and force production. Investigation of the kinematics of the trunk, upper and lower extremity, together with muscle activity of the trunk, provides an insight into the motor control strategies utilized over a typical race. Nine elite female rowers performed a 2000 m race simulation. Kinematic data of the trunk and extremities, together with electromyography (EMG) activity of spinal and pelvic extensor and flexor muscles, were compared at 250 and 1500 m. At 1500 m, there was greater dissociation in the timing of leg extension and arm flexion and delayed trunk extension. Also at 1500 m, the spine demonstrated a delayed peak extension angular velocity of the T4–T7 and L3–S1 spinal segments in the early drive along with delayed and increased peak extension angular velocity of T10–L1 and L1–L3 spinal segments during the late drive. Trunk muscle fatigue was not evident; however, the abdominals demonstrated larger EMG burst areas at 1500 m. Alterations in trunk kinematics suggest that the trunk acts as a less stiff lever on which to transfer the forces of the legs to the arms and handle. Increased abdominal activity may reflect increased demand to control the trunk, given the altered coordination between the legs, trunk and arms.

In-shoe plantar pressure measurements for patients with knee osteoarthritis: Reliability and effects of lateral heel wedges

Although plantar pressure measurement systems are being used increasingly during gait analyses to investigate foot orthotics, there is limited information describing test-retest reliability of such measurements. Objectives of this study were to (1) examine the test-retest reliability of lateral heel pressure (LHP) and centre of pressure (COP) during walking with and without lateral heel wedges, and (2) evaluate the effects of 4° and 8° lateral heel wedges on the magnitude of LHP, the pathway of the COP and the peak external knee adduction moment (KAM) in subjects with and without knee osteoarthritis (OA). Twenty-six subjects, 12 patients with knee OA and 14 healthy subjects, were evaluated during three lateral heel wedge conditions (control, 4° and 8°) with standardized footwear. Three-dimensional analyses of gait with optical motion capture, floor-mounted force plate and in-shoe plantar pressure were completed on two occasions. Intraclass correlation coefficients (ICC(2, 1)) for LHP were excellent (0.79-0.83) while ICCs for COP in the medial-lateral and anterior-posterior directions were more variable (0.66-0.86). Reliability was slightly diminished when using heel wedges. Standard errors of measurement suggested considerable day-to-day variability in an individuals measures. Lateral heel wedges significantly (p<0.001) increased LHP, shifted COP anteriorly and laterally, and decreased the KAM. No significant differences were observed between subjects with and without OA. Although the day-to-day variability appears too large to confidently evaluate changes in individual patients, and decreases in reliability with increases in wedge size indicate caution, these results suggest in-shoe measurement of LHP and COP are appropriate for use in studies evaluating biomechanical effects of foot orthoses for knee OA.

Toe-out, lateral trunk lean, and pelvic obliquity during prolonged walking in patients with medial compartment knee osteoarthritis and healthy controls

To compare the time‐varying behavior of maximum toe‐out angle, lateral trunk lean (over the stance leg), and pelvic obliquity (rise and drop on the swing leg) during prolonged walking in participants with and without medial compartment knee osteoarthritis (OA), and to explore correlations between these gait characteristics and pain.

Effect of tibial re-alignment surgery on single leg standing balance in patients with knee osteoarthritis

BACKGROUND Standing balance is impaired in individuals with knee osteoarthritis and is associated with disease severity. The effects of surgical interventions on standing balance have received little attention. The purpose of the present study was to examine measures of balance during tests of single-limb standing before and after medial opening wedge high tibial osteotomy--a lower limb re-alignment procedure for those with varus alignment and knee osteoarthritis. METHODS Standing balance was assessed in 49 individuals prior to and 12 months following medial opening wedge high tibial osteotomy. Participants performed three trials of single-limb balance lasting 10s each while standing on a force platform. Anteroposterior and mediolateral coordinates of the centre of pressure were obtained from the force platform and used to calculate the total centre of pressure path length as well as the range and variability (standard deviation) of the anteroposterior and mediolateral coordinates. FINDINGS Though all centre of pressure measures were lower following high tibial osteotomy, none reached statistical significance (P>0.05) and effect sizes were small (d<0.34). The largest mean improvement was 7.6% (95% confidence interval: -0.7-15.8%). INTERPRETATION Results indicate that standing balance in individuals with knee osteoarthritis is not significantly different following high tibial osteotomy surgery. Standing balance in this patient population is a complex process not entirely dictated by disease symptoms or structural factors such as alignment.

Effect of Anterior Tibiofemoral Glides on Knee Extension during Gait in Patients with Decreased Range of Motion after Anterior Cruciate Ligament Reconstruction

PURPOSE The purpose of this preliminary investigation was to evaluate the effect of anterior tibiofemoral glides on maximal knee extension and selected spatiotemporal characteristics during gait in patients with knee extension deficits after anterior cruciate ligament (ACL) reconstruction. METHODS Twelve patients with knee-extension deficits after recent ACL reconstructions underwent quantitative gait analyses immediately before and after 10 minutes of repeated anterior tibiofemoral glides on the operative limb, and again after a 10-minute seated rest period. RESULTS Maximum knee extension during stance phase of the operative limb significantly increased immediately after the treatment (mean increase: 2.0°±4.1°, 95% CI: 0.6°-3.3°). Maximum knee extension decreased after the 10-minute rest period (mean decrease: 0.9°±1.8°, 95% CI: -0.1°-1.8°), although the decrease was not statistically significant. Small increases in operative limb step length, stride length, and gait speed were observed after the rest period compared to baseline values only. CONCLUSIONS A single session of anterior tibiofemoral glides increases maximal knee extension during the stance phase of gait in patients with knee-extension deficits. Increases in knee extension are small and short-lived, however, suggesting that continued activity is required to maintain the observed improvements.