Ian Parr
Cubist Pharmaceuticals
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Publication
Featured researches published by Ian Parr.
Bioorganic & Medicinal Chemistry Letters | 2017
Jing Zhang; Audrey Chan; Blaise Lippa; Jason B. Cross; Christopher Liu; Ning Yin; Jan Romero; Jonathan Lawrence; Ryan Heney; Prudencio Herradura; Jennifer Goss; Cynthia Clark; Cassandra Abel; Yanzhi Zhang; Katherine M. Poutsiaka; Felix Epie; Mary Conrad; Azard Mahamoon; Kien T. Nguyen; Ajit Chavan; Edward Clark; Tongchuan Li; Robert K. Y. Cheng; Michael W. Wood; Ole Andreas Andersen; Mark Brooks; Jason Kwong; John J. Barker; Ian Parr; Yugui Gu
The emergence and spread of multidrug-resistant (MDR) Gram negative bacteria presents a serious threat for public health. Novel antimicrobials that could overcome the resistance problems are urgently needed. UDP-3-O-(R-3-hydroxymyristol)-N-acetylglucosamine deacetylase (LpxC) is a cytosolic zinc-based deacetylase that catalyzes the first committed step in the biosynthesis of lipid A, which is essential for the survival of Gram-negative bacteria. Our efforts toward the discovery of novel LpxC inhibitors are presented herein.
Archive | 2000
Jason Hill; Ian Parr; Michael Morytko; Jim Siedlecki; Xiang Yang Yu; Jared Silverman; Dennis Keith; John T. Finn; Dale J. Christensen; Tsvetelina Lazarova; Alan D. Watson; Yan Zhang
Bioorganic & Medicinal Chemistry Letters | 2003
Jason Hill; James Siedlecki; Ian Parr; Michael Morytko; Xiang Yu; Yanzhi Zhang; Jared Silverman; Nicole Controneo; Valerie Laganas; Tongchuan Li; Dennis Keith; George Shimer; John T. Finn
Archive | 2000
Jason Hill; Ian Parr; Michael Morytko; Jim Siedlecki; Xiang Yang Yu; Jared Silverman; Dennis Keith; John Finn; Dale J. Christensen; Tsvetelina Lazarova; Alan D. Watson; Yan Zhang
Bioorganic & Medicinal Chemistry Letters | 2003
James Siedlecki; Jason Hill; Ian Parr; Xiang Yu; Michael Morytko; Yanzhi Zhang; Jared Silverman; Nicole Controneo; Valerie Laganas; Tongchuan Li; Jianshi Li; Dennis Keith; George Shimer; John T. Finn
Archive | 2002
John T. Finn; Michael Morytko; Ian Parr; Michael E. Jung
Archive | 2000
Jason Hill; Ian Parr; Michael Morytko; Jim Siedlecki; Xiang Yang Yu; Jared Silverman; Dennis Keith; John T. Finn; Dale J. Christensen; Tsvetelina Lazarova; Alan D. Watson; Yan Zhang
Archive | 2012
Dale J. Christensen; John Finn; Jason Hill; Dennis Keith; Tsvetelina Lazarova; Michael Morytko; Ian Parr; Jim Siedlecki; Jared Silverman; Alan D. Watson; Xiang Yang Yu; Yan Zhang; アラン ディー． ワトソン，; イアン パール; ジェイソン ヒル; ジム シードレッキ; ジャレッド シルバーマン; シャン ヤン ユ; ジョン フィン; ツヴェテリナ ラザロヴァ; デイル クリステンセン; デニス ケイス; マイケル モリトコ; ヤン チャン
Archive | 2002
John Finn; Michael E. Jung; Michael Morytko; Ian Parr
Archive | 2000
Dale J. Christensen; John Finn; Jason Hill; Dennis Keith; Tsvetelina Lazarova; Michael Morytko; Ian Parr; Jim Siedlecki; Jared Silverman; Alan D. Watson; Xiang Yang Yu; Yan Zhang
