Ikuo Yamamori | Researchain

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International Journal of Hematology | 2005

Severe Hypercholesterolemia Associated with Decreased Hepatic Triglyceride Lipase Activity and Pseudohyponatremia in Patients after Allogeneic Stem Cell Transplantation

Yoshihiro Inamoto; Tamio Teramoto; Koji Shirai; Hideko Tsukamoto; Takaomi Sanda; Koichi Miyamura; Ikuo Yamamori; Noriyuki Hirabayashi; Yoshihisa Kodera

A 55-year-old woman with Ph-negative acute lymphoblastic leukemia in primary induction failure received allogeneic peripheral blood stem cell transplantation from her HLA-compatible sister. Pseudohyponatremia developed due to extreme hypercholesterolemia of 4091 mg/dL accompanied by lipoprotein X and lipoprotein Y. The hypercholesterolemia was caused by cholestasis due to chronic GVHD and ischemic cholangiopathy. In addition, we found that hepatic triglyceride lipase (HTGL) activity was severely decreased, which could be another novel factor causing extreme hypercholesterolemia after allogeneic transplantation. The total cholesterol has been gradually decreasing followed by the improvement of cholestasis with bezafibrate, ursodeoxycholic acid and prednisone treatments, and by a slight increase in HTGL-protein. To our knowledge, this is the first report to describe the association of decreased HTGL with extreme hypercholesterolemia after allogeneic transplantation.

The Journal of Clinical Endocrinology and Metabolism | 1991

Nucleotide Deletion Resulting in Frameshift as a Possible Cause of Complete Thyroxine-Binding Globulin Deficiency in Six Japanese Families

Ikuo Yamamori; Yuichi Mori; Hisao Seo; Yoshifumi Hirooka; Shuji Imamura; Yoshitaka Miura; Nobuo Matsui; Yutaka Oiso

Endocrine Journal | 2014

Adipsia increases risk of death in patients with central diabetes insipidus.

Hiroshi Arima; Toshihiko Wakabayashi; Tetsuya Nagatani; Masazumi Fujii; Akihiro Hirakawa; Takashi Murase; Yuko Yambe; Tsutomu Yamada; Fumiko Yamakawa; Ikuo Yamamori; Masako Yamauchi; Yutaka Oiso

The Journal of Clinical Endocrinology and Metabolism | 1994

A truncated thyroxine-binding globulin due to a frameshift mutation is retained within the rough endoplasmic reticulum: a possible mechanism of complete thyroxine-binding globulin deficiency in Japanese

Yoshitaka Miura; Fukushi Kambe; Ikuo Yamamori; Yuichi Mori; Yoshiyuki Tani; Yasutaka Murata; Yutaka Oiso; Hisao Seo

Biochemistry | 1991

Molecular cloning and primary structure of rat thyroxine-binding globulin

Shuji Imamura; Yuichi Mori; Yoshiharu Murata; Ikuo Yamamori; Yoshitaka Miura; Yutaka Oiso; Hisao Seo; Nobuo Matsui; Samuel Refetoff

Endocrine Journal | 2004

Appearance of Thyroid Stimulating and Blocking Immunoglobulins after Bone Marrow Transplantation : Presentation of Two Contrasting Cases

Ikuo Yamamori; Tadaharu Kanie; Naoko Maeda; Yoshihisa Kodera; Takaharu Matsuyama; Haruhiko Hasegawa

Endocrine Journal | 1993

Sequence of a variant thyroxine-binding globulin (TBG) in a family with partial TBG deficiency in Japanese (TBG-PDJ).

Yoshitaka Miura; Yuichi Mori; Ikuo Yamamori; Yoshiyuki Tani; Yoshiharu Murata; Masaaki Yoshimoto; Eiichi Kinoshita; Tadashi Matsumoto; Yutaka Oiso; Hisao Seo

Internal Medicine | 1999