Ileana Linčir

The Effect of Saliva on the Formation of KOH-Soluble Fluoride after Topical Application of Amine Fluoride Solutions of Varying Fluoride Concentration and pH

The effect of saliva on the amount of KOH-soluble fluoride formed on a sound enamelsurface after application of amine fluoride solution of varying fluoride concentrations (1, 0.5 and 0.25% F) and pH (5.3, 4.5 and 4.0) was examined in an in vitro study. The saliva pretreatment increased the amount of KOH-soluble fluoride at the highest pH value. For any given fluoride concentration, the presence of saliva did not influence the amount of KOH-soluble fluoride. These data suggest that saliva could enhance the amount of KOH-soluble fluoride if the topical fluoride preparations are not highly acid.

Anticaries Effect of Different Amine Fluoride Concentrations in Schoolchildren

A double-blind 3-year clinical trial was conducted in a nonfluoridated water community in which 354 schoolchildren aged 9-10 years were assigned randomly to three groups (A, B and C) and subjected to a treatment with 1 of 3 different concentrations of amine fluoride solution every 2 months. Clinical examinations were conducted at baseline and after 1, 2, and 3 years. For group A (positive control) receiving topical applications of amine fluoride solution (1%), the 3-year DMFT and DMFS increments were 4.0 +/- (SD) 2.7 and 8.5 +/- 5.6, respectively. For group B (0.5% F), the DMFT and DMFS increments were 4.4 +/- 3.0 and 8.4 +/- 5.7, respectively; these differences being statistically not significant. The mean caries increments in group C (0.25% F) were 5.1 +/- 2.9 for DMFT and 10.0 +/- 5.5 for DMFS. The differences in incremental caries scores between group C and groups A or B were statistically significant (p < 0.05). Thus, the amine fluoride solution, in which the fluoride content was reduced by half, provided similar caries reductions in schoolchildren as did a standard amine fluoride solution with 1.0% F.

Caries-preventive effect of two different topical fluoride concentrations with two different frequencies of application in preschool children.

The effects of standard topical amine fluoride solution (1% F) and a low-fluoride solution (0.5% F) with two different frequencies of application (5 and 10 times a year) on 2 years dental caries increment were compared in a double-blind clinical trial involving 199 kindergarten children. The results suggest that increased frequency of application of a low fluoride topical solution (10 times a year) may provide caries protection in preschool children with relatively high caries activity.