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Imad H. Hanna

Vanderbilt University

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Publication

Featured researches published by Imad H. Hanna.

Archives of Biochemistry and Biophysics | 1998

Role of the Alanine at Position 363 of Cytochrome P450 2B2 in Influencing the NADPH- and Hydroperoxide-Supported Activities☆☆☆

Imad H. Hanna; John F. Teiber; Kristin L Kokones; Paul F. Hollenberg

Archives of Biochemistry and Biophysics | 2000

Expression of human cytochrome P450 2B6 in Escherichia coli: characterization of catalytic activity and expression levels in human liver.

Imad H. Hanna; James R. Reed; F. Peter Guengerich; Paul F. Hollenberg

Archives of Biochemistry and Biophysics | 1998

Recombinant human cytochrome P450 1B1 expression in Escherichia coli

Tsutomu Shimada; Rebecca M. Wunsch; Imad H. Hanna; Thomas R. Sutter; F. P. Guengerich; Elizabeth M. J. Gillam

Biochemistry | 2003

Role of glutamic acid 216 in cytochrome P450 2D6 substrate binding and catalysis

F. Peter Guengerich; Imad H. Hanna; Martha V. Martin; Elizabeth M. J. Gillam

Biochemistry | 2002

Diversity in the Oxidation of Substrates by Cytochrome P450 2D6: Lack of an Obligatory Role of Aspartate 301−Substrate Electrostatic Bonding†

F. Peter Guengerich; Grover P. Miller; Imad H. Hanna; Martha V. Martin; Serge Leger; Cameron Black; Nathalie Chauret; José M. Silva; Laird A. Trimble; James A. Yergey; Deborah A. Nicoll-Griffith

Archives of Biochemistry and Biophysics | 2001

Heterologous expression of cytochrome P450 2D6 mutants, electron transfer, and catalysis of bufuralol hydroxylation: the role of aspartate 301 in structural integrity.

Imad H. Hanna; Mi-Sook Kim; F. Peter Guengerich

Journal of Biological Chemistry | 2002

Oxidation of Methoxyphenethylamines by Cytochrome P450 2D6 ANALYSIS OF RATE-LIMITING STEPS

F. Peter Guengerich; Grover P. Miller; Imad H. Hanna; Hideaki Sato; Martha V. Martin

Biochemistry | 1998

MOLECULAR BASIS FOR THE DIFFERENCES IN LIDOCAINE BINDING AND REGIOSELECTIVITY OF OXIDATION BY CYTOCHROMES P450 2B1 AND 2B2

Imad H. Hanna; Elizabeth S. Roberts; Paul F. Hollenberg

Journal of Biological Chemistry | 2001

Diversity in Mechanisms of Substrate Oxidation by Cytochrome P450 2D6 LACK OF AN ALLOSTERIC ROLE OF NADPH-CYTOCHROME P450 REDUCTASE IN CATALYTIC REGIOSELECTIVITY

Imad H. Hanna; Joel A. Krauser; Hongliang Cai; Mi-Sook Kim; F. Peter Guengerich

Biochemistry | 2001

Oxidation of phenethylamine derivatives by cytochrome P450 2D6: the issue of substrate protonation in binding and catalysis.

Grover P. Miller; Imad H. Hanna; Nishimura Y; Guengerich Fp

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F. Peter Guengerich

Vanderbilt University

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Paul F. Hollenberg

University of Michigan

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Grover P. Miller

University of Arkansas for Medical Sciences

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Martha V. Martin

Vanderbilt University

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Hongliang Cai

Vanderbilt University

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Mi-Sook Kim

Vanderbilt University

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Nishimura Y

Vanderbilt University

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Elizabeth M. J. Gillam

University of Queensland

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Bhavani Dhanabalasingam

Wayne State University

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Cameron Black

Merck

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