Imelda Olivas-Armendariz

Scaffolds for Tissue Engineering Via Thermally Induced Phase Separation

Tissue engineering is a multidisciplinary field that uses engineering materials called scaffolds to support cell seeding and biochemical factors with the aim to regenerate biological function of a tissue or organ, in this process typically there are involve three main components. Biochemical Factors, such as growth factors, proteins that stimulate proliferation and differentiation cell. Cells which can perform the appropriate tissue functions regenerating the lost or damage tissue, and scaffolds that will act as artificial extracellular matrix that provides mechanical support to cells.

Synthesis and Characterization of Porous Polyurethane- Chitosan Blends

In this work the synthesis and characterization of polyurethane (PU)-chitosan(CH) porous prepared by thermal induced phase separation (TIPS) is described, the obtained products were characterized by thermo gravimetric analysis (TGA) and differential scanning calorimetry (DSC), evidence of the interaction between both polymers was acquired from infrared spectroscopy. The morphology of the scaffolds was studied by scanning electron microscopy also the mechanical properties were acquired. The results showed that the TIPS technique is appropriate for the production of PU-CH porous materials.

Chitosan/Mimosa tenuiflora films as potential cellular patch for skin regeneration

Bio-composites films were prepared by casting and drying of aqueous solutions containing different weight ratios of chitosan and bark of Mimosa tenuiflora. The physico-chemical and functional properties of the films were characterized by scanning electron microscopy, dynamical mechanical analysis, wettability, cytotoxicity and in vitro antibacterial activities. The morphology studies confirmed that the presence of Mimosa tenuiflora change the surface of films. Moreover, the incorporation of Mimosa tenuiflora improved the thermal stability of the films, as it was indicated by the changes in the glass temperatures obtained. Water-uptake ability changed in relation to polymeric composition of film. This property increased by the addition of Mimosa tenuiflora to the film. Improved antibacterial properties were measured against Escherichia Coli and Micrococcus lysodeikticus or luteus. Finally, cytotoxicity was studied by MTT assay and the films were non-toxic. These preliminary results provide a cheap way to prepare chitosan/Mimosa tenuiflora films for wound healing and skin regeneration.

Apósitos de polímeros naturales para regeneración de piel

This review includes the bio-polymers most used in recent years for the manufacturing of materials used as dressings in cutaneous wound healing and skin rege...

Synthesis and Characterization of Polyurethane Scaffolds for Biomedical Applications

Polyurethanes are interesting materials that can be used in biomedical applications for regeneration of bone tissue. In this work the synthesis and characterization of porous polyurethanes to act as scaffold is performed by a thermally induced phase separation technique. The appropriate parameters are determined in order to obtain a porous well interconnected material. Characterization by thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC) is made in order to determine the thermal stability of the material. Chemical characterization is made by Fourier transformed infrared spectroscopy with attenuated total reflectance (FTIR-ATR). The morphology of the material is observed by a field emission scanning electron microscope (FESEM) and the mechanical properties are measured by dynamic mechanical analysis (DMA).