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Dive into the research topics where Inger B. Schipper is active.

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Featured researches published by Inger B. Schipper.


Journal of Trauma-injury Infection and Critical Care | 2008

Advanced trauma life support, 8th edition, the evidence for change.

John B. Kortbeek; Saud A. Al Turki; Jameel Ali; Jill A. Antoine; Bertil Bouillon; Karen J. Brasel; Fred Brenneman; Peter R. Brink; Karim Brohi; David Burris; Reginald A. Burton; Will Chapleau; Wiliam Cioffi; Francisco de Salles Collet e Silva; Art Cooper; Jaime Cortés; Vagn Eskesen; John J. Fildes; Subash Gautam; Russell L. Gruen; Ron Gross; K S. Hansen; Walter Henny; Michael J. Hollands; Richard C. Hunt; Jose M. Jover Navalon; Christoph R. Kaufmann; Peggy Knudson; Amy Koestner; Roman Kosir

The American College of Surgeons Committee on Traumas Advanced Trauma Life Support Course is currently taught in 50 countries. The 8th edition has been revised following broad input by the International ATLS subcommittee. Graded levels of evidence were used to evaluate and approve changes to the course content. New materials related to principles of disaster management have been added. ATLS is a common language teaching one safe way of initial trauma assessment and management.


Journal of Bone and Joint Surgery-british Volume | 2004

Treatment of unstable trochanteric fractures: RANDOMISED COMPARISON OF THE GAMMA NAIL AND THE PROXIMAL FEMORAL NAIL

Inger B. Schipper; Ewout W. Steyerberg; René Castelein; F. H. W. M. van der Heijden; P. T. den Hoed; Albert J.H. Kerver; A.B. van Vugt

The proximal femoral nail (PFN) is a recently introduced intramedullary system, designed to improve treatment of unstable trochanteric fractures of the hip. In a multicentre prospective clinical study, the intra-operative use, complications and outcome of treatment using the PFN (n = 211) were compared with those using the gamma nail (GN) (n = 213). The intra-operative blood loss was lower with the PFN (220 ml v 287 ml, p = 0.001). Post-operatively, more lateral protrusion of the hip screws of the PFN (7.6%) was documented, compared with the gamma nail (1.6%, p = 0.02). Most local complications were related to suboptimal reduction of the fracture and/or positioning of the implant. Functional outcome and consolidation were equal for both implants. Generally, the results of treatment of unstable trochanteric fractures were comparable for the PFN and GN. The pitfalls and complications were similar, and mainly surgeon- or fracture-related, rather than implant-related.


International Orthopaedics | 2011

Use and efficacy of bone morphogenetic proteins in fracture healing

Suzanne N. Lissenberg-Thunnissen; David J. J. de Gorter; Cornelis F. M. Sier; Inger B. Schipper

PurposeThis review evaluates the application of bone morphogenetic proteins (BMPs) in delayed bone repair, aiming at a broad audience from clinicians to scientists. Next to an overview of the role of the different BMPs, their antagonists and their current applications, special attention is focused on new scientific developments improving the effects of BMP-based therapy for bone repair.MethodsPublication searches in PubMed and Embase revealed 850 relevant articles on the criteria ‘BMP’ AND ‘bone repair’ (as of May 2011). The abstracts were carefully reviewed and papers were selected according to the content.ResultsThe resulting publications showed that BMP-2 and BMP-7 are clearly the most extensively evaluated BMPs, in general with positive results on bone healing, comparable to the use of unspecific preparations such as autologous bone grafts or platelet-rich plasma.ConclusionsAlthough the efficacy of BMPs as stimulators of bone repair has been demonstrated in model systems and clinical studies, the use of BMPs to enhance fracture healing in the clinical setting is still controversial. Issues such as when, where and how much of which BMP is the most effective and profitable to use still have to be elucidated. But optimisation of the BMP products used in combination with cheaper production methods will inevitably stimulate the clinical use of BMPs for bone fracture healing in the near future.


British Journal of Surgery | 2004

Beneficial effect of helicopter emergency medical services on survival of severely injured patients.

Sander P. G. Frankema; A.N. Ringburg; Ewout W. Steyerberg; M. J. R. Edwards; Inger B. Schipper; A.B. van Vugt

In Rotterdam, the Netherlands, a helicopter‐transported medical team (HMT), staffed with a trauma physician, provides additional therapeutic options at the scene of injury. This study evaluated the influence of the HMT on the chance of survival of severely injured trauma victims.


Journal of Orthopaedic Science | 2007

Percutaneous treatment of displaced intra-articular calcaneal fractures

Tim Schepers; Inger B. Schipper; Lucas Vogels; Abida Z. Ginai; Paul G.H. Mulder; Martin J. Heetveld; Peter Patka

BackgroundThe outcome after displaced intra-articular calcaneal fractures is influenced by the condition of the surrounding soft tissues. To avoid secondary soft tissue complications after surgical treatment, several less-invasive procedures for reduction and fixation have been introduced. The percutaneous technique according to Forgon and Zadravecz is suitable for all types of displaced intra-articular calcaneal fractures and was therefore introduced in our clinic. The aim of this study was to evaluate the long-term outcome of percutaneous treatment according to Forgon and Zadravecz in patients with displaced intra-articular calcaneal fractures.MethodsA cohort of patients with displaced intra-articular calcaneal fractures treated with percutaneous surgery was retrospectively defined. Clinical outcome was evaluated by standardized physical examination, radiographs, three published outcome scores, and a visual analogue scale of patient satisfaction.ResultsFifty patients with 61 calcaneal fractures were included. After a mean follow-up period of 35 months, the mean values of the Maryland foot score, the Creighton-Nebraska score, and the American Orthopaedic Foot and Ankle Society score were 79, 76, and 83 points out of 100, respectively. The average visual analogue scale was 7.2 points out of 10. The average range of motion of the ankle joint was 90% of normal and subtalar joint movements were almost 70% compared with the healthy side or normal values. Superficial wound complications occurred in seven cases (11%) and deep infections in two (3%). A secondary arthrodesis of the subtalar joint was performed in five patients and was scheduled in four patients (15%).ConclusionsCompared with the outcome of historic controls from randomized trials and meta-analyses, this study indicates favorable results for the percutaneous technique compared with the open technique. Despite similar rates of postoperative infection and secondary arthrodesis, the total outcome scores and preserved subtalar motion are overall good to excellent.


Journal of Trauma-injury Infection and Critical Care | 2011

Prevalence and prognostic factors of disability after major trauma.

A.N. Ringburg; Suzanne Polinder; Marie Catherine P. van Ierland; Ewout W. Steyerberg; Esther M.M. Van Lieshout; Peter Patka; Eduard F. van Beeck; Inger B. Schipper

BACKGROUND The primary aim of this study was to assess the health-related quality of life of survivors of severe trauma 1 year after injury, specified according to all the separate dimensions of the EuroQol-5D (EQ-5D) and the Health Utilities Index (HUI). METHODS A prospective cohort study was conducted in which all severely injured trauma patients presented at a Level I trauma center were included. After 12 months, the EQ-5D, HUI2 and HUI3 were used to analyze the health status. RESULTS Follow-up assessments were obtained from 246 patients (response rate, 68%). The overall population EQ-5D (median) utility score was 0.73 (EQ-5D Dutch general population norm, 0.88). HUI2, HUI3, and EQ-5D Visual Analog Scale scores were 0.81, 0.65, and 70, respectively. Eighteen percent had at least one functional limitation 1 year after trauma, and 60% reported functional limitations on two or more domains using the EQ-5D. The female gender and comorbidity were significant independent predictors of disability. CONCLUSION Functional outcome and quality of life of survivors of severe injury have not returned to normal 1 year after trauma. The prevalence of specific limitations in this population is very high (40-70%). Female gender and comorbidity are predictors of long-term disability.


Prehospital Emergency Care | 2009

Validity of helicopter emergency medical services dispatch criteria for traumatic injuries: a systematic review

A.N. Ringburg; Gijs de Ronde; Siep S. Thomas; Esther M.M. Van Lieshout; Peter Patka; Inger B. Schipper

Objective. This review provides an overview of the validity of Helicopter Emergency Medical Services (HEMS) dispatch criteria for severely injured patients. Methods. A systematic literature search was performed. English written and peer-reviewed publications on HEMS dispatch criteria were included. Results. Thirty-four publications were included. Five manuscripts discussed accuracy of HEMS dispatch criteria. Criteria based upon Mechanism of Injury (MOI) have a positive predictive value (PPV) of 27%. Criteria based upon the anatomy of injury combined with MOI as a group, result in an undertriage of 13% and a considerable overtriage. The criterion ‘loss of consciousness’ has a sensitivity of 93–98% and a specificity of 85–96%. Criteria based on age and/or comorbidity have a poor sensitivity and specificity. Conclusion. Only 5 studies described HEMS dispatch criteria validity. HEMS dispatch based on consciousness criteria seems promising. MOI criteria lack accuracy and will lead to significant overtriage. The first categories needing revision are MOI and age/comorbidity.


Prehospital Emergency Care | 2010

Intraosseous Devices: A Randomized Controlled Trial Comparing Three Intraosseous Devices

Klaas A. Hartholt; Esther M.M. Van Lieshout; Wim C. Thies; Peter Patka; Inger B. Schipper

Abstract Introduction. Access to the circulation is mandatory for adequate treatment in medical emergency situations. Intraosseous (IO) infusion is a safe, fast, and effective alternative for gaining access to the circulation, if intravenous access fails. In the last decade, the IO method gained renewed interest. New devices have been developed, such as the Bone Injection Gun (BIG) 15G/18G and the First Access for Shock and Trauma 1 (FAST1). Objective. To determine which IO needle is preferable for gaining IO access in patients requiring acute administration of fluids or medication in a prehospital setting. Methods. In this single-blind prospective randomized trial, the IO needles were added to the equipment of the helicopter emergency medical services (HEMS) system. The HEMS nurses received training in proper use of all needles. Children (1–13 years) were randomized to the Jamshidi 15G or the BIG 18G, and adults (≥ 14 years) were randomized to the Jamshidi 15G, the BIG 15G, or the FAST1. All patients requiring acute administration of fluids or medication, without successful insertion of an intravenous (IV) catheter, were included. The IO needles were compared in terms of insertion time, success rate, bone marrow aspiration, adverse events during placement, and user satisfaction. Results. Sixty-five adult and 22 pediatric patients were included. The treatment groups were similar with respect to age, gender, mortality, and trauma mechanism (p ≥ 0.05). The median insertion times ranged from 38 seconds for the Jamshidi 15G to 49 seconds for the BIG 15G and 62 seconds for the FAST1 (p = 0.004). The devices did not differ with respect to success rates (adults overall 80% and children overall 86%), complication rates, and user satisfaction. Conclusions. The Jamshidi 15G needle could be placed significantly faster than the FAST1. The devices had similar success rates, complication rates, and user-friendliness. Intraosseous devices provide a safe, simple, and fast method for gaining access to the circulation in emergency situations.


Emergency Medicine Journal | 2008

Prehospital interventions: time wasted or time saved? An observational cohort study of management in initial trauma care

M. W A van der Velden; A.N. Ringburg; Engelbert Bergs; Ewout W. Steyerberg; Peter Patka; Inger B. Schipper

Objective: Preclinical actions in the primary assessment of victims of blunt trauma may prolong the time to definitive clinical care. The aim of this study was to examine the duration of performed interventions and to study the effect of on-scene time (OST) and interventions performed before admission to hospital on hospital resuscitation time. Methods: 147 consecutive patients with high-energy blunt trauma aged ⩾15 years were studied prospectively. Prehospital time intervals and interventions were documented and compared with hospital data collected from continuous digital video registration. Analyses were performed with correction for injury severity and type of prehospital medical assistance (emergency medical services (EMS) versus physician-staffed helicopter emergency medical services (HEMS)). Results: Primary survey and initial treatment were initiated and completed within 1 h of arrival of the EMS. 83% of this “golden hour” elapsed out of hospital and 81% (n = 224) of all interventions (n = 275) were carried out before admission to hospital. An increase in the number of prehospital interventions was associated with an increased OST (p<0.001). Subanalyses showed no such correlation in the HEMS group. The HEMS group had a longer mean OST than the EMS group (p<0.001) with relatively more prehospital interventions (p<0.001) and a shorter mean in-hospital primary survey time with fewer in-hospital interventions. Overall, OST and the number of prehospital interventions were not related to in-hospital primary survey time and interventions. Conclusion: For most trauma patients the initial life- and limb-saving care is achieved within the “golden hour”. Prehospital treatment occupies most of the golden hour. More prehospital interventions were performed with HEMS than with EMS only, but the higher number of interventions did not result in a longer OST with HEMS. Although the numbers of subsequent in-hospital interventions may be lower, no reduction in time in hospital may be expected from the interventions performed before hospital admission.


International Journal of Emergency Medicine | 2011

Current methods of diagnosis and treatment of scaphoid fractures

Steven J. Rhemrev; Daan Ootes; Frank J. P. Beeres; Sven Meylaerts; Inger B. Schipper

Fractures of the scaphoid bone mainly occur in young adults and constitute 2-7% of all fractures. The specific blood supply in combination with the demanding functional requirements can easily lead to disturbed fracture healing. Displaced scaphoid fractures are seen on radiographs. The diagnostic strategy of suspected scaphoid fractures, however, is surrounded by controversy. Bone scintigraphy, magnetic resonance imaging and computed tomography have their shortcomings. Early treatment leads to a better outcome. Scaphoid fractures can be treated conservatively and operatively. Proximal scaphoid fractures and displaced scaphoid fractures have a worse outcome and might be better off with an open or closed reduction and internal fixation. The incidence of scaphoid non-unions has been reported to be between 5 and 15%. Non-unions are mostly treated operatively by restoring the anatomy to avoid degenerative wrist arthritis.

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Pieta Krijnen

Leiden University Medical Center

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Peter Patka

Erasmus University Rotterdam

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A.N. Ringburg

Erasmus University Rotterdam

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Ewout W. Steyerberg

Erasmus University Rotterdam

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Cornelis F. M. Sier

Leiden University Medical Center

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W.R. Spanjersberg

Erasmus University Rotterdam

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Suzanne Polinder

Erasmus University Rotterdam

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Sylvia A. Stegeman

Leiden University Medical Center

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