Irene Buvat
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Publication
Featured researches published by Irene Buvat.
The Journal of Nuclear Medicine | 2008
Florent C. Sureau; Andrew J. Reader; Claude Comtat; Claire Leroy; Maria-Joao Ribeiro; Irene Buvat; Regine Trebossen
Brain PET in small structures is challenged by low resolution inducing bias in the activity measurements. Improved spatial resolution may be obtained by using dedicated tomographs and more comprehensive modeling of the acquisition system during reconstruction. In this study, we assess the impact of resolution modeling (RM) during reconstruction on image quality and on the estimates of biologic parameters in a clinical study performed on a high-resolution research tomograph. Methods: An accelerated list-mode ordinary Poisson ordered-subset expectation maximization (OP-OSEM) algorithm, including sinogram-based corrections and an experimental stationary model of resolution, has been designed. Experimental phantom studies are used to assess contrast and noise characteristics of the reconstructed images. The binding potential of a selective tracer of the dopamine transporter is also assessed in anatomic volumes of interest in a 5-patient study. Results: In the phantom experiment, a slower convergence and a higher contrast recovery are observed for RM-OP-OSEM than for OP-OSEM for the same level of statistical noise. RM-OP-OSEM yields contrast recovery levels that could not be reached without RM as well as better visual recovery of the smallest spheres and better delineation of the structures in the reconstructed images. Statistical noise has lower variance at the voxel level with RM than without at matched resolution. In a uniform activity region, RM induces higher positive and lower negative correlations with neighboring voxels, leading to lower spatial variance. Clinical images reconstructed with RM demonstrate better delineation of cortical and subcortical structures in both time-averaged and parametric images. The binding potential in the striatum is also increased, a result similar to the one observed in the phantom study. Conclusion: In high-resolution PET, RM during reconstruction improves quantitative accuracy by reducing the partial-volume effects.
Society of Nuclear Medicine Annual Meeting Abstracts | 2007
Perrine Tylski; Nicolas Grotus; P. Giraud; Jean Claude Rosenwald; Irene Buvat
ORASIS - Journées francophones des jeunes chercheurs en vision par ordinateur | 2013
Vincent Jaouen; Paulo González; Simon Stute; Irene Buvat; Denis Guilloteau; Clovis Tauber
Society of Nuclear Medicine Annual Meeting Abstracts | 2010
Jacques Maisonobe; Simon Stute; Hatem Necib; Irene Buvat
Society of Nuclear Medicine Annual Meeting Abstracts | 2014
S. Burg; Fabien Hyafil; Liliane Louedec; S. Leygnac; Pauline Huet; Dominique Le Guludec; Irene Buvat
Society of Nuclear Medicine Annual Meeting Abstracts | 2013
Pauline Huet; S. Burg; Fabien Hyafil; Dominique Le Guludec; Irene Buvat
Society of Nuclear Medicine Annual Meeting Abstracts | 2012
S. Burg; Alexandre Dupas; Simon Stute; Arnaud Dieudonné; Milan Milliner; Dominique Le Guludec; Irene Buvat
Society of Nuclear Medicine Annual Meeting Abstracts | 2012
Clovis Tauber; Abhinay D. Joshi; Irene Buvat; Denis Guilloteau; Mark Mintun
Society of Nuclear Medicine Annual Meeting Abstracts | 2011
Clovis Tauber; Simon Stute; Irene Buvat; M.J. Santiago-Ribeiro; Sylvie Chalon; Denis Guilloteau
Society of Nuclear Medicine Annual Meeting Abstracts | 2008
Nicolas Grotus; Andrew J. Reader; Simon Stute; Jean-Claude Rosenwald; P. Giraud; Irene Buvat