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Featured researches published by Irie Tetsumi.


International Journal of Pharmaceutics | 1988

Effect of bile on the intestinal absorption of α-cyclodextrin in rats

Irie Tetsumi; Tsunenari Yoshinobu; Uekama Kaneto; Josef Pitha

Abstract The effect of bile on the absorption of α-cyclodextrin from rat small intestine was examined using the in situ recirculating perfusion technique. Only very little intestinal absorption of α-cyclodextrin was observed when the bile duct was ligated, but some of it was absorbed from the intestine when bile was present; intact α-cyclodextrin then entered the systemic circulation. Sodium cholate and disodium ethylenediaminetetraacetate also promoted the absorption of α-cyclodextrin under the bile duct-ligated conditions and their promoting effects were completely inhibited by the addition of calcium choride. These results indicate that absorption of α-cyclodextrin from the intestine occurs through the paracellular pathway.


International Journal of Pharmaceutics | 1987

Alleviation in protriptyline-photosensitized skin irritation by di-O-methyl-β-cyclodextrin complexation

Hoshino Teruhiko; Ishida Kazuhisa; Irie Tetsumi; Hirayama Fumitoshi; Uekama Kaneto


Archive | 1989

4-BIPHENYLYLACETIC ACID ESTER-CYCLODEXTRIN INCLUSION COMPOUND

Kamikama Kanehito; Hirayama Fumitoshi; Irie Tetsumi; Arima Hidetoshi


Archive | 2017

Additional file 3: Figure S1. of Predictive factors for effectiveness and safety of enoxaparin for total knee arthroplasty in aged Japanese patients: a retrospective review

Sonoda Akihiro; Kondo Yuki; Tsuneyoshi Yasuhiro; Iwashita Yoshitaka; Nakao Shoji; Ishida Kazuhisa; Oniki Kentaro; Saruwatari Junji; Irie Tetsumi; Ishitsuka Yoichi


日本薬学会九州支部大会講演要旨集 | 2016

Niemann‐Pick病C型モデルマウスにおける2‐Hydroxypropyl‐β‐cyclodextrin脳室内投与時の血清中Gpnmb濃度の変動

Shirakawa Seiichi; Ishizuka Yoichi; Kondo Yuki; Takeo Tooru; Nakagata Naomi; Era Takumi; Higashi Taishi; Motoyama Keiichi; Arima Hidetoshi; Kurauchi Yuki; Katsuki Hiroshi; Matsuo Muneaki; Higaki Katsumi; Ono Kosaku; Irie Tetsumi


日本薬学会九州支部大会講演要旨集 | 2015

Niemann‐Pick病C型治療薬としての2‐Hydroxypropyl‐cyclodextrinsの有効性・安全性評価

Yamada Ikuyo; Ishizuka Yoichi; Kondo Yuki; Takeo Tooru; Nakagata Naoki; Era Takumi; Higashi Taishi; Motoyama Keiichi; Arima Hidetoshi; Matsuo Muneaki; Higaki Katsumi; Ono Kosaku; Irie Tetsumi


日本薬学会九州支部大会講演要旨集 | 2015

Niemann‐Pick病C型のモデル細胞を用いた2‐Hydroxypropyl‐β‐cyclodextrinの効果の時間依存性

Nakajima Yuka; Soga Minami; Hamasaki Makoto; Kondo Yuki; Ishizuka Yoichi; Era Takumi; Irie Tetsumi


臨床血液 | 2014

2‐ヒドロキシプロピル‐β‐シクロデキストリンは新規抗腫瘍薬として作用する

Kubota Yasushi; Yokoo Masako; Motoyama Keiichi; Higashi Taishi; Taniyoshi Masatoshi; Tokumaru Hiroko; Tabe Yoko; Sueoka Eisaburo; Arima Hidetoshi; Irie Tetsumi; Kimura Shinya


Archive | 2003

PREPARADO PARA ABSORCION PERCUTANEA.

Uekama Kaneto; Irie Tetsumi; Hara Michio; Horiuchi Yasuhide


Archive | 2002

PREPARACAO QUE PODE SER ABSORVIDA POR VIA PERCUTANEA

Uekama Kaneto; Irie Tetsumi; Hara Michio; Horiuchi Yasuhide

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Josef Pitha

National Institutes of Health

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