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Archive | 1990

3-propenylcephem derivative

Takashi Kamiya; Toshihiko Naito; Shigeto Negi; Yuuki Komatu; Yasunobu Kai; Takaharu Nakamura; Isao Sugiyama; Yoshimasa Machida; Seiichiro Nomoto; Kyosuke Kitoh; Kanemasa Katsu; Hiroshi Yamauchi


Archive | 1989

Process for the preparation of cephem derivatives and intermediates therefor

Takashi Kamiya; Toshihiko Naito; Yuuki Komatu; Yasunobu Kai; Takaharu Nakamura; Manabu Sasho; Shigeto Negi; Isao Sugiyama; Kanemasa Katsu; Hiroshi Yamauchi


The Journal of Antibiotics | 1992

Synthesis and structure-activity relationships of a new series of cephalosporins, E1040 and related compounds

Isao Sugiyama; Yuuki Komatsu; Hiroshi Yamauchi


Archive | 1987

3-propenylcephem derivative, preparation thereof, chemical intermediates therein, pharmaceutical composition and use

Takashi Kamiya; Toshihiko Naito; Shigeto Negi; Yuuki Komatu; Yasunobu Kai; Takaharu Nakamura; Isao Sugiyama; Yoshimasa Machida; Seiichiro Nomoto; Kyosuke Kitoh; Kanemasa Katsu; Hiroshi Yamauchi


Archive | 1982

Novel penicillin and cephalosporin compounds, a process for preparing the same and antibacterial composition containing the novel compounds

Yoshimasa Machida; Isao Saito; Isao Sugiyama; Shigeto Negi; Seiichiro Nomoto; Hironori Ikuta; Hiroshi Yamauchi; Kyosuke Kitoh


Archive | 1990

3-substituted vinyl cephalosporin derivatives

Manabu Sasho; Hiroshi Yamauchi; Motosuke Yamanaka; Takaharu Nakamura; Kanemasa Katsu; Isao Sugiyama; Yuuki Komatu; Shigeto Negi


The Journal of Antibiotics | 1994

Studies on orally active cephalosporins. I: Synthesis and structure-activity relationships of new 3-substituted carbamoyloxymethyl cephalosporins

Shigeto Negi; Motosuke Yamanaka; Isao Sugiyama; Yuki Komatsu; Manabu Sasho; Akihiko Tsuruoka; Atsushi Kamada; Itaru Tsukada; Ryoichi Hiruma; Kanemasa Katsu; Yoshimasa Machida


Archive | 1991

7-Acyl-3-(substituted carbamoyloxy) cephem compounds, use thereof and process for their preparation

Shigeto Negi; Motosuke Yamanaka; Kanemasa Katsu; Isao Sugiyama; Yuuki Komatu; Atsushi Kamata; Akihiko Tsuruoka; Yoshimasa Machida


Archive | 1986

Cephem compounds having at the 3-position a (1,4-methylene-1-piperidinio)methyl group or a (1-quinuclidinio)methyl group

Hiroshi Yamauchi; Isao Sugiyama; Isao Saito; Seiichiro Nomoto; Takashi Kamiya; Yoshimasa Machida; Shigeto Negi


The Journal of Antibiotics | 1992

ROLE OF THE AMINOTHIADIAZOLYL GROUP IN THE ANTIPSEUDOMONAL ACTIVITY OF CEFCLIDIN

Naoaki Watanabe; Isao Sugiyama

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