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Dive into the research topics where J A Frank is active.

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Featured researches published by J A Frank.


Journal of Computer Assisted Tomography | 1988

Gadolinium DTPA enhanced MR imaging of ACTH-secreting microadenomas of the pituitary gland

J L Doppman; J A Frank; Andrew J. Dwyer; Edward H. Oldfield; Donald L. Miller; Lynnette K. Nieman; George P. Chrousos; Gordon B. Cutler; D. Lynn Loriaux

Gadolinium diethylenetriamine pentaacetic acid (DTPA) enhanced magnetic resonance imaging was performed in eight patients with Cushing disease and surgically proven pituitary microadenomas. A 1.5 T scanner was used with 3 mm contiguous slices. Short repetition times (TR), short echo times (TE), and long TR, long TE sequences were obtained before and serially after intravenous administration of Gd-DTPA. Three of eight (38%) microadenomas were undetectable both without and with Gd-DTPA: one post-Gd-DTPA scan was false positive on the side opposite the adenoma. Hemihypophysectomy based on a petrosal sinus adrenocorticotropic hormone (ACTH) gradient cured all three patients. Two microadenomas (25%) were visible as hypointense foci following Gd-DTPA but not on unenhanced scans. The remaining three microadenomas (38%) were seen before and after Gd-DTPA on T1-weighted images. In this small series of ACTH-producing microadenomas, one-third were seen on unenhanced 1.5 T scans, one-third were seen only after Gd-DTPA, and one-third were not imaged even with Gd-DTPA enhancement.


Radiology | 1990

Metabolism of human gliomas: Assessment with H-1 MR spectroscopy and F-18 fluorodeoxyglucose PET

Jeffry R. Alger; J A Frank; Alberto Bizzi; Michael J. Fulham; Bryan X. DeSouza; Michael O. Duhaney; Susan W. Inscoe; Jeanette L. Black; Peter C. M. van Zijl; Chrit T. W. Moonen; Giovanni Di Chiro


Science | 1990

Functional magnetic resonance imaging in medicine and physiology

Chrit T. W. Moonen; P. C. M. Van Zijl; J A Frank; D Le Bihan; Edwin D. Becker


Radiology | 1989

Dynamic Gd-DTPA-enhanced MR imaging of the kidney: experimental results.

Peter L. Choyke; J A Frank; Mary Girton; Susan W. Inscoe; Mark J. Carvlin; Jeanette L. Black; H A Austin; Andrew J. Dwyer


Radiology | 1988

Short-Ti inversion-recovery pulse sequence: analysis and initial experience in cancer imaging.

Andrew J. Dwyer; J A Frank; V J Sank; J W Reinig; A M Hickey; J L Doppman


Radiology | 1988

Meningeal carcinomatosis in the VX2 rabbit tumor model: detection with Gd-DTPA-enhanced MR imaging.

J A Frank; Mary Girton; Andrew J. Dwyer; Donald C. Wright; P J Cohen; J L Doppman


Radiology | 1988

Spinal cord artifacts from truncation errors during MR imaging.

L M Levy; G. Di Chiro; Rodney A. Brooks; Andrew J. Dwyer; Louis Wener; J A Frank


Radiology | 1986

Cerebrospinal fluid rhinorrhea: depiction with MR cisternography in dogs.

G. Di Chiro; M E Girton; J A Frank; M. J. Dietz; O A Gansow; Donald C. Wright; Andrew J. Dwyer


Radiology | 1987

Ocular and cerebral metastases in the VX2 rabbit tumor model: contrast-enhanced MR imaging.

J A Frank; Mary Girton; Andrew J. Dwyer; P J Cohen; S Lightman; O A Gansow; Martin W. Brechbiel; J L Doppman


Annual Review of Physiology | 1992

The Utilization of Magnetic Resonance Imaging in Physiology

Jeffry R. Alger; J A Frank

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Andrew J. Dwyer

National Institutes of Health

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Mary Girton

National Institutes of Health

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Chrit T. W. Moonen

National Institutes of Health

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Donald C. Wright

George Washington University

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G. Di Chiro

National Institutes of Health

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J W Reinig

National Institutes of Health

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Jeanette L. Black

National Institutes of Health

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