Network


Latest external collaboration on country level. Dive into details by clicking on the dots.

Hotspot


Dive into the research topics where J. A. Murray is active.

Publication


Featured researches published by J. A. Murray.


Journal of Trauma-injury Infection and Critical Care | 1997

Penetrating Left Thoracoabdominal Trauma: The Incidence and Clinical Presentation of Diaphragm Injuries

J. A. Murray; Demetrios Demetriades; Edward E. Cornwell; Juan A. Asensio; George C. Velmahos; Howard Belzberg; T. V. Berne

OBJECTIVEnThe objective of this study was to (1) determine the incidence of diaphragmatic injuries in penetrating left thoracoabdominal trauma and (2) evaluate the role of laparoscopy in detecting clinically occult diaphragmatic injuries.nnnPATIENTS AND METHODSnOne hundred nineteen consecutive patients with penetrating injuries to the left thoracoabdominal region presenting to Los Angeles County-University of Southern California Medical Center were prospectively evaluated during an 8-month period. Either celiotomy (with hemodynamic instability or peritonitis) or laparoscopy was performed. Results of the clinical examination and roentgenographic findings were recorded preoperatively.nnnRESULTSnOne hundred seven patients were fully evaluated. Fifty patients required emergent celiotomy. Fifty-seven patients underwent laparoscopy. The overall incidence of diaphragmatic injuries was 42% (59% for gunshot wounds, 32% for stab wounds). Among the 45 patients with diaphragmatic injuries, 31% had no abdominal tenderness, 40% had a normal chest roentgenogram, and 49% had an associated hemopneumothorax. Fifteen of the patients undergoing laparoscopy (26%) had occult diaphragm injuries.nnnCONCLUSIONn(1) The incidence of diaphragmatic injuries in association with penetrating left thoracoabdominal trauma is high. (2) The clinical and roentgenographic findings are unreliable at detecting occult diaphragmatic injuries. (3) Laparoscopy is a vital tool for detecting occult diaphragmatic injuries among patients who have no other indications for formal celiotomy.


Journal of Trauma-injury Infection and Critical Care | 2000

Helical computed tomographic scan in the evaluation of mediastinal gunshot wounds.

David Hanpeter; Demetrios Demetriades; Juan A. Asensio; Thomas V. Berne; George C. Velmahos; J. A. Murray

BACKGROUNDnThe standard evaluation of mediastinal gunshot wounds usually requires angiography and either esophagoscopy or esophagography. In the present study, we have evaluated the role of helical computed tomographic (CT) scanning in reducing the need for angiographic and esophageal studies.nnnMETHODSnThis was a prospective study of patients with mediastinal gunshot wounds who were hemodynamically stable and would otherwise require angiography and esophageal evaluation. All patients underwent CT scan of the chest with intravenous contrast to delineate the missile trajectory. If the missile tract was in close proximity to the aorta, great vessels, or esophagus, then traditional evaluation with angiographic or esophageal evaluation was pursued.nnnRESULTSnA total of 24 patients met the inclusion criteria and underwent CT scan evaluation of their mediastinal gunshot wounds. One patient was taken for sternotomy to remove a missile embedded in the myocardium solely on the basis of the result of the CT scan. Because of proximity of the bullet tract, 12 patients required additional evaluation with eight angiograms and nine esophageal studies. One of these patients had a positive angiogram (bullet resting against the ascending aorta) and underwent sternotomy for missile removal; all other studies were negative. The remaining 11 patients were found to have well-defined missile tracts that approached neither the aorta nor the esophagus, and no additional evaluation was pursued. There were no missed mediastinal injuries in this group. Overall, 12 of 24 patients (50%) had a change in management (either received an operation or avoided additional radiographic or endoscopic evaluation) on the basis of the CT scan.nnnCONCLUSIONnThe helical CT scan provides a rapid, readily available, noninvasive means to evaluate missile trajectories. This permits accurate assessment of potential mediastinal injury and reduces the need for routine angiographic and esophageal studies.


Journal of Trauma-injury Infection and Critical Care | 1996

Mortality and prognostic factors in penetrating injuries of the aorta.

Demetrios Demetriades; Dimitrios Theodorou; J. A. Murray; Juan A. Asensio; Edward E. Cornwell; George C. Velmahos; Howard Belzberg; T. V. Berne

PURPOSEnThis study was designed to investigate the epidemiology and prognostic factors determining survival in penetrating injuries of the aorta.nnnPATIENTS AND METHODSnThis was a retrospective analysis of all patients with penetrating aortic injuries, admitted to a large, level I trauma center. The following factors were analyzed for their role in determining survival: mechanism of injury, anatomical site of the aortic injury, initial blood pressure on admission, need for emergency room thoracotomy, and the introduction of a dedicated trauma program with an attending surgeon in-house.nnnRESULTSnThere were 93 patients with penetrating aortic injuries over a 5-year period. The abdominal aorta was injured in 67 patients (72%) and the thoracic aorta in 26 (28%). Most of the victims (82.5%) were admitted in shock and 41% had an unrecordable blood pressure on admission. Victims with injury to the thoracic aorta were more likely to have an unrecordable blood pressure on admission than patients with abdominal aortic injuries (73% vs 28.4%), and more likely to require an emergency room thoracotomy (76.9% vs 20.9%). Thirty-four patients (36.6%) required an emergency room thoracotomy and there were no survivors. The overall mortality was 80.6% (87.5% for gunshot injuries, 64.7 % for knife injuries). Patients with abdominal aortic injuries were three times more likely to survive than those with thoracic aortic injuries (23.9% vs 7.7%). The introduction of a dedicated trauma program, which resulted in significant reduction of mortality in other types of severe trauma, had no effect on the outcome in aortic injuries.nnnCONCLUSIONSnPenetrating aortic injuries still have a very high mortality rate with no improvement in survival despite improved trauma services. Injury to the thoracic aorta, gunshot wounds, unrecordable blood pressure on admission, and the need for emergency room thoracotomy, are important predictors of high mortality.


Journal of Trauma-injury Infection and Critical Care | 1996

Transcervical gunshot injuries: mandatory operation is not necessary.

Demetrios Demetriades; Dimitrios Theodorou; Edward E. Cornwell; Juan A. Asensio; Howard Belzberg; George C. Velmahos; J. A. Murray; T. V. Berne

BACKGROUNDnIt has been suggested that all transcervical gunshot wounds should be explored surgically because of the high incidence of injuries to vital structures. The present prospective study investigated the clinical presentation, the role of various diagnostic investigations, and the need for surgery in patients with transcervical gunshot injuries.nnnMETHODSnNinety-seven patients sustained gunshot injuries to the neck and 33 of them (34%) were transcervical. All victims were assessed clinically according to a written protocol and subsequently were evaluated angiographically, and, in the appropriate case, by means of endoscopy and esophagography.nnnRESULTSnOverall, 24 (73%) of the 33 patients with transcervical gunshot wounds had injuries to cervical structures. Vascular injuries were found in 48%, spinal cord injuries in 24%, and aerodigestive tract injuries in 6% of patients with transcervical injuries. In the 64 patients without midline crossing, the incidence of cervical structure injuries was 31%. Despite the high incidence of injuries to cervical structures in transcervical wounds, only 21% of the patients had a therapeutic operation. The overall mortality was 3%. There were no in-hospital deaths or local complications in the nonoperatively managed group.nnnCONCLUSIONSnThe results of the present study do not support the current recommendations of mandatory operation for all transcervical gunshot wounds. A careful clinical examination combined with the appropriate diagnostic investigations should determine the treatment modality. About 80% of these patients can safely be managed nonoperatively.


Journal of Trauma-injury Infection and Critical Care | 1997

Occult Injuries to the Diaphragm: Prospective Evaluation of Laparoscopy in Penetrating Injuries to the Left Lower Chest

J. A. Murray; Demetrios Demetriades; Juan A. Asensio; Edward E. Cornwell; George C. Velmahos; Howard Belzberg; John D. Berne; T. V. Berne

BACKGROUNDnTo evaluate the incidence of occult diaphragmatic injuries and investigate the role of laparoscopy in patients with penetrating trauma to the left lower chest who lack indications for exploratory celiotomy other than the potential for a diaphragm injury.nnnSTUDY DESIGNnPatients with penetrating injuries to the left lower chest who were hemodynamically stable and without indications for a celiotomy were prospectively evaluated with diagnostic laparoscopy to determine the presence of an injury to the left hemidiaphragm. Diagnostic laparoscopy was performed in the operating room under general anesthesia.nnnRESULTSnOne-hundred-ten patients (94 stab wounds, 16 gunshot wounds) were evaluated with laparoscopy. Twenty-six (24%) diaphragmatic injuries were identified (26% for stab wounds and 13% for gunshot wounds). Comparison of patients with diaphragmatic injuries with those without diaphragmatic injuries demonstrated a slightly greater incidence of hemo/pneumothoraces (35% versus 24%, NS). The incidence of diaphragmatic injuries in patients with a normal chest x-ray was 21% versus 31% for patients with a hemo/pneumothorax. An elevated left hemidiaphragm was associated with a diaphragmatic injuries in only 1 of 7 patients (14%). The incidence of diaphragmatic injuries was similar for anterior, lateral, and posterior injuries (22%, 27%, and 22% respectively).nnnCONCLUSIONSnThe incidence of occult diaphragmatic injuries in penetrating trauma to the left lower chest is high, 24%. These injuries are associated with a lack of clinical and radiographic findings, and would have been missed had laparoscopy not been performed. Patients with penetrating trauma to the left lower chest who do not have any other indication for a celiotomy should undergo videoscopic evaluation of the left hemidiaphragm to exclude an occult injury.


American Surgeon | 2000

Fetal death after trauma in pregnancy.

Dimitrios Theodorou; George C. Velmahos; Irene Souter; Linda S. Chan; Raymond Tatevossian; J. A. Murray; Demetrios Demetriades


American Surgeon | 1997

Factors predicting prolonged mechanical ventilation in critically injured patients : Introducing a simplified quantitative risk score

George C. Velmahos; Howard Belzberg; Linda S. Chan; Avari S; Cornwell Ee rd; T. V. Berne; Juan A. Asensio; J. A. Murray; Demetrios Demetriades


American Surgeon | 1999

Abdominal computed tomography scan in pediatric blunt abdominal trauma.

E. M. Sievers; J. A. Murray; D. Chen; George C. Velmahos; Demetrios Demetriades; T. V. Berne


Journal of Trauma-injury Infection and Critical Care | 1996

Carotid injury: postrevascularization hemorrhagic infarction.

J. A. Murray; Demetrios Demetriades; Juan A. Asensio


New horizons (Baltimore, Md.) | 1996

Use of large databases for resolving critical care problems.

Howard Belzberg; J. A. Murray; William C. Shoemaker; Edward E. Cornwell; Oder D; Guenon J; George C. Velmahos; Demetrios Demetriades

Collaboration


Dive into the J. A. Murray's collaboration.

Top Co-Authors

Avatar

Demetrios Demetriades

University of Southern California

View shared research outputs
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar

Howard Belzberg

University of Southern California

View shared research outputs
Top Co-Authors

Avatar

T. V. Berne

University of Southern California

View shared research outputs
Top Co-Authors

Avatar
Top Co-Authors

Avatar

John D. Berne

University of Southern California

View shared research outputs
Top Co-Authors

Avatar

Dimitrios Theodorou

National and Kapodistrian University of Athens

View shared research outputs
Top Co-Authors

Avatar

Linda S. Chan

University of Southern California

View shared research outputs
Top Co-Authors

Avatar
Researchain Logo
Decentralizing Knowledge