J Alix
Institut de veille sanitaire
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AIDS | 1997
F F Hamers; Veronique L. Batter; A M Downs; J Alix; Françoise Cazein; Jean-Baptiste Brunet
Objectives:To evaluate the magnitude and trends of the HIV epidemic associated with injecting drug use in Europe. Methods:AIDS cases associated with injecting drug users (IDU) diagnosed through 1995 were analysed, including IDU, homo-/bisexual IDU, heterosexual partners of IDU and children whose mothers were IDU. HIV seroprevalence studies among IDU were reviewed. Results:Of the 171 932 cumulative AIDS cases, 73 119 (43%) were IDU-associated (IDU, 89.0%; homo-/bisexual IDU, 3.5%; heterosexual partners of IDU, 6.2%; children with IDU mothers, 1.4%). Over 90% of IDU-associated cases were concentrated in south-western European countries with considerably higher rates in Spain (124 cases per million in 1995) than elsewhere (Italy, 68 per million; Portugal, 42 per million; France, 38 per million). During 1990–1995, incidence increased at an average annual rate of 11% overall and > 23% in central and eastern Europe; overall, incidence increased in older persons (12%) while decreasing in those aged 13–24 years (by 6%). HIV prevalence in IDU showed considerable geographic variation across and within countries. In several countries of western Europe, prevalence decreased. In the former Soviet Union, large HIV outbreaks have recently been detected among IDU through systematic HIV testing (e.g., in Ukraine, 6750 HIV infections were diagnosed in IDU tested during 1995–1996). Conclusions:IDU have played a major role in the spread of HIV in Europe. In several western European countries, the incidence of HIV acquired through drug use has declined following high rates in mid-1980s. Studies to assess current transmission are needed and prevention efforts must be maintained. In eastern Europe, emerging epidemics reinforce the urgency for prevention.
Journal of Acquired Immune Deficiency Syndromes | 2003
F F Hamers; A Infuso; J Alix; A M Downs
&NA; AIDS reporting has been the principal means of monitoring the HIV/AIDS situation in Europe since 1989. HIV reporting was set up at the European level in 1999, although it has existed in most European countries since the 1980s. Anonymous individual data on AIDS and, if available, new HIV diagnoses, and data on HIV prevalence in various populations are reported from the 51 countries of the WHO European Region to EuroHIV. Aggregate data on HIV prevalence in various populations. Data are presented after grouping the 51 countries into three geographic areas: the West, Center, and East. At end of 2000, in the West, AIDS incidence continued to decline except among those infected heterosexually; numbers of newly diagnosed HIV infections are relatively stable, but rising among heterosexually infected persons, many of whom originate from countries with generalized HIV epidemics. In the East, numbers of newly diagnosed HIV cases (mostly injection drug users) continue to rise steeply, particularly in the Russian Federation, Latvia, and Estonia. In the Center, levels of HIV and AIDS remain low. HIV reporting is becoming a central element of HIV/AIDS surveillance in Europe. Heterogeneity between countries in health care systems, HIV testing patterns and surveillance systems remain challenging for data standardization at the European level. Efforts should be made to use surveillance data for evaluating the effectiveness of HIV/AIDS prevention interventions.
AIDS | 2007
G Likatavicius; F F Hamers; A M Downs; J Alix; Anthony Nardone
Introduction:The comparison of HIV prevalence among blood donations in European countries provides an indication of the relative safety of the blood supply in different countries and over time. Methods:Data between 1990 and 2004 on annual numbers of blood donations and HIV prevalence in blood donations were collected from national correspondents in the 52 countries of the World Health Organization European Region. Data are presented for three geographic areas: West, Centre and East. Results:Since 1990, the number of blood donations has declined by 43% in the East and by 26% in the Centre, while remaining relatively stable in the West. In 2004, the number of blood donations was more than twice as high in the West in comparison with the East and the Centre. Over the same period, HIV prevalence among blood donations increased dramatically in the East, remained stable in the Centre and declined in the West. Since 2001, HIV prevalence levels of more than 10 per 100 000 donations were reported from six countries in the East (with a high of 128/100 000 in Ukraine), whereas in the rest of Europe the reported national HIV prevalence levels were lower than 10/100 000 donations. The prevalence of HIV was much lower among donations from repeat donors than from first-time donors. Conclusion:In some eastern European countries public health interventions, such as deferring individuals at risk of HIV infection from donating blood and constituting a pool of regular donors, are urgently needed to assure the safety of the blood supply.
Eurosurveillance | 2006
F F Hamers; Devaux I; J Alix; A Nardone
Eurosurveillance | 2000
A Infuso; F F Hamers; A M Downs; J Alix
Eurosurveillance | 2007
Magid Herida; J Alix; Devaux I; Likatavicius G; J C Desenclos; Matic S; Ammon A; A Nardone
The Lancet | 1995
RosemaryA. Ancelle-Park; J Alix; AngelaM. Downs; Jean-Baptiste Brunet
The Lancet | 1995
Rosemary Ancelle-Park; J Alix; AngelaM. Downs; Jean-Baptiste Brunet
Eurosurveillance | 2001
F F Hamers; J Alix; Caroline Semaille; H Pilkington; A M Downs
Eurosurveillance | 1996
Françoise Cazein; F F Hamers; J Alix; J B Brunet