J.E. Anderson

The position of the Radin blood group locus in relation to other chromosome 1 loci

Data are presented which indicate that the Radin blood group antigen is governed by a locus, for the present called Rd, which is located between PGM1 and αFUC Rh, and is either very closely linked to or identical with Sc.

Polymorphism of the sixth component of complement (C6) in the dog

Isoelectric focusing was used to identify five alleles at the locus determining the production of the sixth component of complement (C6) in the dog. Four of these alleles, C61, C62, C64,and C65,were studied in family pedigrees and shown to be inherited in a codominant autosomal fashion. All alleles except for C64occurred commonly in the multiple breeds tested.

Analysis of linkage relationships of Co, Jk and K with each other and with chromosome 2 loci ACP1 and Km.

Linkage analyses of locus pairs involving ACPI, Co, Jk, K and Km indicate: probable linkage between Co and Jk (ẑ=+3.80 at θ= 0.29); possible linkage between Jk and Km (z =+1.93 at θ= 1.30); a mild hint of linkage between Co and K 9z=+1.01 at θ= 0.30); inadequate information for Co: Km linkage for K: Jk, K: Km, ACPI: Jk, ACPI: K and ACPI: Km. The compiled information does not allow assignment of Co, Jk or K to chromosome 2.

No Support for Sex-Esterase D Phenotype Association

No distortion was found when the genetics of esterase D (EC 3.1.1.1) in family data was examined for sex-phenotype ratio.