J. García Palacios

Systematic Design of Production Processes for Enantiomers with Integration of Chromatography and Racemisation Reactions

Abstract A systematic study is performed of integrated processes that combine chromatographic separation and racemisation reaction for production of pure enantiomers. In a theoretical case study, processes of different degrees of integration are investigated by optimization of corresponding models. Concepts studied range from reactor-separator-recycle systems to fully integrated schemes with distributed reactivity. Physico-chemical parameters were determined experimentally for a model system. Data are reported together with first results for a simple flowsheet-integrated process.