J. Gillman

The modifying influence of diet and the physical environment on spontaneous tumour frequency in rats.

The Modifying Influence of Diet and the Physical Environment on Spontaneous Tumour Frequency in Rats

A simple dietary technique for the production of hepatic necrosis with a consideration of the factors preventing the lesion.

A simple dietary technique is described for the production of hepatic necrosis. The liver lesion develops consistently in rats weighing between 30 and 200 gm. at the commencement of the experiment. The time of onset of necrosis, however, is a function of the age of the rat.

ASPECTS OF NUTRITIONAL LIVER DISEASE—HUMAN AND EXPERIMENTAL

In this communication we propose, first to examine the relationships of hepatic fibrosis to antecedent fatty change and to necrosis of the liver in malnourished human beings and in animals fed various diets and, secondly, to consider methodological problems of nutritional research, particularly as they affect the assessment of the role of specific food factors in promoting or preventing liver disease.

COMPLETE RESTITUTION OF THE LIVER IN RATS FOLLOWING NECROSIS AND FIBROSIS OF DIETARY ORIGIN

Both acute necrosis and fibrosis of the liver of dietary origin in rats can be followed by complete restitution of structure in an appropriate dietary setting.

The prevention of experimentally induced reticulo-sarcoma by hypothyroidism.

Die Entstehung von Reticulosarkom bei Ratten nach mehrmaliger Injektion von Trypanblau kann unterdrückt werden durch Entkräftung, Verabreichung anti-thyreoidaler Mittel und durch alle andern Faktoren, welche den Stoffwechsel herabsetzen.

The participation of the adrenal and thyroid in fat metabolism in hypophysectomized baboons (Papio ursinus)

1. Im Gegensatz zum Hund entwickelt sich beim Pavian keine Fettleber nach Hypophysektomie oder Thyreoidektomie oder nach einer Kombination dieser beiden Eingriffe. 2. Thyroxin wirkt als Antagonist hemmend auf die Fettbildung, die durch Cortison beim hypophysektomierten Pavian angeregt wird. 3. Starke Leberverfettung entsteht bei hypophysektomierten Pavianen nach gleichzeitiger Entziehung von Cortison und Thyroxin.