J. Grant Thomson

The results of surgical treatment of trigger finger

A three-part retrospective study was undertaken to review the long-term results of surgical treatment of trigger finger. Seventy-five patients were identified by chart review. Fifty-nine of these were assessed by a telephone survey, with a mean follow-up period of 48 months (range, 6-70 months). Forty-six patients (78%) underwent follow-up physical examination. Surgical treatment was successful in all patients. Ninety-seven percent of patients had complete resolution of triggering, and the rest had significant improvement of symptoms. The recurrence rate was 3%, with only a single patient requiring reoperation. Complications were infrequent and resulted in minimal morbidity. No nerve injuries, tendon bowstringing, or ulnar deviation of the digits were observed. There were no wound infections. Although steroid injections should remain the initial remedy for most trigger fingers, surgical intervention is highly successful for conservative treatment failures and should be considered for patients desiring quick and definitive relief from this disability.

Long-Term Outcome of Embolotherapy and Surgery for High-Flow Extremity Arteriovenous Malformations

PURPOSE To assess the long-term efficacy of embolotherapy in combination with surgery for management of symptomatic high-flow arteriovenous malformations (HFAVMs) of the lower and upper extremities. MATERIALS AND METHODS Twenty consecutive patients with symptomatic high-flow lower extremity AVMs (LE-AVMs; n = 9) and upper extremity AVMs (UE-AVMs; n = 11) were treated from 1982 to 1999. All nine patients with LE-AVM had pain and seven had ulceration of the skin. All 11 patients with UE-AVM had debilitating pain, seven had weakness of the affected hand, and two had bony erosion. Embolization of the nidus beneath the site of maximum pain or ulceration was performed percutaneously from the femoral artery through coaxially placed microcatheters (n = 18) or surgical cutdown (n = 2). Cyanoacrylate (isobutyl or n-butyl) diluted with iophendylate or ethiodized oil was used in 19 of 20 patients. RESULTS Follow-up was completed in eight of nine patients with LE-AVM (mean, 8.6 y) and nine of 11 patients with UE-AVM (mean, 7.4 y) after treatment. One patient with localized LE-AVM was functioning well 13 years after embolotherapy and another was functioning well 16 years after undergoing three embolotherapy procedures and two skin grafts. Five of nine patients with LE-AVM required below-the-knee (n = 4) or above-the-knee (n = 1) amputation 1-6 years after technically and clinically successful embolotherapy. All three trifurcation arteries were diffusely involved in HFAVM in patients requiring amputation. Healing of the two amputation sites, involved by AVM at the knee, was excellent after preoperative geniculate artery embolotherapy. All 11 patients with UE-AVM experienced marked symptomatic improvement; seven after embolotherapy alone and the other four after resection of AVM. One complication of digital spasm was reversed by administration of nerve blocks. CONCLUSIONS LE-AVM with diffuse involvement of all three trifurcation arteries ultimately required amputation because of recurrence of symptoms after technically and clinically successful embolotherapy. Cyanoacrylate embolotherapy alone or in combination with surgical resection of the AVM provided excellent long-term palliation in patients with UE-AVM.

The extended lateral arm free flap for head and neck reconstruction: the Yale experience.

The lateral arm free flap (LAFF) has been chosen by some head and neck reconstructive microsurgeons to be their fasciocutaneous free flap of choice. The qualities of this flap have been suggested to include its consistent vascular anatomy, its thin and pliable nature, and its reinnervation capabilities, as well as its low donor site morbidity and ease of closure. During the past year we have performed 14 head and neck reconstructions using the extended LAFF (ELAFF). We present our indications for its use and review its shortcomings. Although the ELAFF does have its limitations, including variability in its flap thickness and donor vessel size, it unquestionably is an important flap in head and neck reconstruction and is our flap of choice for soft tissue reconstruction.

Early passive mobilization after digital nerve repair and grafting in a fresh cadaver

In the clinical management of combined tendon and nerve injuries, there are competing treatment strategies. Isolated tendon injuries should be rapidly mobilized after repair to prevent adhesion formation, whereas isolated nerve repairs are usually immobilized to prevent disruption and to allow axon regrowth. Recommendations in the published literature for the management of combined tendon and nerve injuries are vague and advise up to 3 weeks of immobilization. The goals of this study were to determine which length of nerve gap resulted in rupture of a repair following postoperative mobilization with the modified Duran protocol and with unrestricted motion and to determine whether nerve grafts are at risk of rupture after mobilization. A total of 100 digital nerves from 10 cadaver hands were tested with the modified Duran and the unsplinted protocols. Each digital nerve on each hand was sequentially resected and repaired at five progressively larger gap lengths after testing with both protocols. The mean nerve gaps at which disruption occurred were significantly different between the splinted (9.7 ± 0.8 mm, n = 100) and unsplinted (7.3 ± 1.9 mm, n = 100) protocols (t test, p < 0.001). One hundred percent of repairs remained intact, with up to 5 mm of resection with the modified Duran protocol (n= 100) and with up to 2.5 mm of resection with the unsplinted protocol (n = 100). All nerve grafts remained intact after mobilization within a dorsal‐blocking splint (n = 100). Considering mechanical integrity of the nerve repair only, these data suggest that early mobilization with tendon protocols may be considered after a nerve injury to avoid the detrimental tendon sequelae that result from immobilization. The adequacy of functional recovery of mobilized nerves is yet to be determined. (Plast. Reconstr. Surg. 108: 386, 2001.)

Surface Area Measurement of the Female Breast: Phase I. Validation of a Novel Optical Technique

Background: Breast shape is largely determined by the volume of tissue and surface area of the skin envelope. Values for breast surface area have never been published in the literature. The investigators have developed an inexpensive, noninvasive optical method to objectively measure breast volume and surface area, and its accuracy is determined. Methods: An optical grid is projected onto the breast, and two images are captured to create a computerized three-dimensional model from which volume, surface area, and maximum vertical projection are calculated. Results: To assess accuracy, simple geometric shapes (n = 22) were analyzed, and the actual volume, surface area, and maximum vertical projection were compared with the imaged values using least-squares linear regression. There was excellent correlation in all three parameters (r > 0.995, p < 10−14). The mean differences in volume, surface area, and maximum vertical projection were 28 ± 28 ml (mean ± SD), 2 ± 9 cm, and 0.4 ± 0.5 cm, respectively. Female breasts (n = 14) were then analyzed, and the actual volume and surface area were measured using plaster casts. Based on least-squares linear regression, there was excellent correlation between the imaged values and actual values (r > 0.992, p < 10−11), and the mean differences in volume and surface area were 32 ± 22 ml and 3 ± 11 cm2, respectively. Conclusions: For the first time, an optical method has been demonstrated to measure volume and surface area with accuracy. When the method is applied to the breast, measurement errors are small and clinically insignificant. The ability to facilitate quantitative breast surgery will be investigated in future phases of this experiment.

Carpal Tunnel Syndrome Associated with the Use of Aromatase Inhibitors in Breast Cancer

Aromatase inhibitors (AI) inhibit peripheral conversion of androgens to estradiol and are commonly used as hormonal therapy for postmenopausal women with hormone receptor-positive breast cancer in the metastatic and adjuvant settings. Joint-related symptoms, however, are seen in a significant proportion of patients. Carpal tunnel syndrome (CTS) is a common nerve entrapment disorder affecting the median nerve. We describe 6 patients with newly diagnosed CTS after initiation of adjuvant AI therapy. Aromatase inhibitors were discontinued in several patients secondary to this toxicity with some switching to tamoxifen and most subsequently experiencing relief of their symptoms. Potential pathophysiologic roles of hormonal manipulation with AIs and other risk factors that might contribute to CTS are discussed. Aromatase inhibitors might accentuate the occurrence of CTS and potentially other nerve entrapment syndromes, and a more systematic approach should be used to better understand the clinical significance and incidence of these symptoms.

Helping Hands: A Cost-Effectiveness Study of a Humanitarian Hand Surgery Mission

Purpose. Congenital anomalies and injuries of the hand are often undertreated in low-middle income countries (LMICs). Humanitarian missions to LMICs are commonplace, but few exclusively hand surgery missions have been reported and none have attempted to demonstrate their cost-effectiveness. We present the first study evaluating the cost-effectiveness of a humanitarian hand surgery mission to Honduras as a method of reducing the global burden of surgically treatable disease. Methods. Data were collected from a hand surgery mission to San Pedro Sula, Honduras. Costs were estimated for local and volunteer services. The total burden of disease averted from patients receiving surgical reconstruction was derived using the previously described disability-adjusted life years (DALYs) system. Results. After adjusting for likelihood of disability associated with the diagnosis and likelihood of the surgerys success, DALYs averted totaled 104.6. The total cost for the mission was

Mild intraoperative hypothermia reduces free tissue transfer thrombosis.

45,779 (USD). The cost per DALY averted was calculated to be

The Effect of Core Temperature on the Success of Free Tissue Transfer

437.80 (USD), which is significantly below the accepted threshold of two times the per capita gross national income of Honduras. Conclusions. This hand surgery humanitarian mission trip to Honduras was found to be cost-effective. This model and analysis should help in guiding healthcare professionals to organize future plastic surgery humanitarian missions.

The effect of ischemic preconditioning on secondary ischemia in myocutaneous flaps.

Patients undergoing free tissue transfer are particularly susceptible to hypothermia. The goal was to investigate the impact of intraoperative core body temperature on free flap thrombosis. Two hundred twelve cases of free flap reconstruction at Yale-New Haven Hospital between 1992 and 2008 were reviewed. Free flap thrombosis was defined by complete flap necrosis or direct visualization of arterial or venous thrombosis. Temperature measurements were calibrated to bladder temperatures as measured by Foley catheter sensor. Through logistic regression analysis, maximum and minimum intraoperative temperatures were determined to be statistically significant predictors of free flap thrombosis. The optimal temperature was calculated to be 36.2 °C, and maximum intraoperative temperatures between 36.0 °C and 36.4 °C showed lower thrombosis rates than super-warmed patients ( P < 0.03). Therefore, free flap patients should be mildly hypothermic at 36.0 °C to 36.4 °C, compared with normothermia at 37.5 °C, as measured in the bladder. A prospective randomized trial investigating thrombosis rates and intraoperative temperature should be undertaken.