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Featured researches published by J. I. Alexander.


Survey of Anesthesiology | 1973

THE EFFECT OF UPPER ABDOMINAL SURGERY ON THE RELATIONSHIP OF AIRWAY CLOSING POINT TO END TIDAL POSITION

J. I. Alexander; P. W. Horton; W. T. Millar; R. K. Parikh; Alastair A. Spence

1. The relationship between end tidal position (ETP) and the point of lung emptying at which there is significant airways closure (CP) has been investigated before and after upper abdominal surgery in thirty-one patients. 2. A significant negative correlation between the index (ETP-CP) and the alveolar-arterial Po, difference (A-aDo,) was found. 3. Nineteen of these patients had a vagotomy and drainage operation and, in this group, there was a greater fall in ETP than in CP in the first and second postoperative days. 4. It is suggested that airway closure is a contributory factor to the known hypoxaemia following abdominal surgery.


BJA: British Journal of Anaesthesia | 1973

THE ROLE OF AIRWAY CLOSURE IN POSTOPERATIVE HYPOXAEMIA

J. I. Alexander; Alastair A. Spence; R. K. Parikh; B. Stuart


Clinical Science | 1972

The Effect of Upper Abdominal Surgery on the Relationship of Airway Closing Point to End Tidal Position

J. I. Alexander; P. W. Horton; W. T. Millar; R. K. Parikh; Alastair A. Spence


International Anesthesiology Clinics | 1972

Pulmonary consequences of abdominal and thoracic surgery.

Alastair A. Spence; J. I. Alexander


Proceedings of the Royal Society of Medicine | 1972

Mechanisms of postoperative hypoxaemia.

Alastair A. Spence; J. I. Alexander


BJA: British Journal of Anaesthesia | 1971

Lung volume changes in relation to airway closure in the postoperative period: a possible mechanism of postoperative hypoxaemia.

J. I. Alexander; Horton Pw; Millar Wt; Alastair A. Spence


Survey of Anesthesiology | 1972

POSTOPERATIVE ANALGESIA AND LUNG FUNCTION

J. I. Alexander; R. K. Parikh; Alastair A. Spence


BJA: British Journal of Anaesthesia | 1972

Further studies on the role of airways closure in postoperative hypoxaemia.

J. I. Alexander; Hamilton W; R. K. Parikh; Alastair A. Spence; Stewart B


Survey of Anesthesiology | 1974

POSTOPERATIVE ANALGESIA AND LUNG FUNCTION: A COMPARISON OF NARCOTIC ANALGESIC REGIMENS

J. I. Alexander; R. K. Parikh; Alastair A. Spence


Survey of Anesthesiology | 1973

MECHANISMS OF POSTOPERATIVE HYPOXAEMIA

Alastair A. Spence; J. I. Alexander

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