J.J. Wang

EP-1332: Clinical results of Nimotuzumab Plus DDP and concurrent radiotherapy for primary cervix cancer

Material and Methods: Thirty-four patients were included in a period from 1994 until 2013. Patients’ charts were reviewed to obtain patients’, treatment and tumor characteristics. DVH parameters were analyzed after reconstruction of the original brachytherapy plan plus delineation of intermediate risk CTV (CTVIR) and organs at risk. The target volume at time of BT was the GTVres and was defined by the treating doctor based on clinical examination and CT scan. The CTVIR was defined by the tumor extension at time of diagnosis. Survival rates were calculated using the Kaplan-Meier method. Morbidity was scored by CTCAE v3.0.

EP-1387: Thermoluminescent dosimetry of the model BT-125-1 125I interstitial brachytherapy seed

Purpose/Objective: To study the dosimetric parameters of dose rate constant, radial dose functions and anisotropy functions for the model BT-125-1 I seed with thermoluminescent dosimeters. Materials and Methods: The preliminary experiment is to study repeatability, linearity of dose response, dose rate effect and energy response of the thermoluminescent dosimeters (TLD). The seed was placed perpendicularly in the center of the PMMA phantom, and 12 TLDs were placed parallel to the source long axis at radial distance of 1 cm with 30°increments, to study the dose rate constant of the model BT-125-1 I seed; the TLDs were placed at radial distances of 0.5, 0.7, 1.0 to 10.0 cm with a 0.5 cm increment and a 5° step, to study the radial dose functions of the model BT-125-1 I seed. The seed was placed horizontally in the center of the PMMA phantom, and the TLDs were placed vertically to the longitudinal axis of the seed at radial distances of 0.5, 1, 1.5, 2, 3 to 7 cm with a 1 cm increment, and polar angles in 20° increments at the radial distance of 0.5 cm, while polar angles in 10° increments at the other radial distances, to study the anisotropy functions of the model BT-125-1 I seed. Results: For the model BT-125-1 I seed, the maximum deviation of repeatability for TLDs was 4.0%. The TLDs had linear dose response without dose rate effect, but the dose response is energy dependent. The dose rate constant, radial dose functions and anisotropy functions were similar to the model 6711 I presented in the TG43 U1 report. Conclusions: The thermoluminescent dosimetry presented the dose rate constant, radial dose functions and anisotropy functions of the model BT-125-1 I seed which were similar to those of model 6711 I seed presented in the TG43U1 report.