Network


Latest external collaboration on country level. Dive into details by clicking on the dots.

Hotspot


Dive into the research topics where J.-L. Lin is active.

Publication


Featured researches published by J.-L. Lin.


European Journal of Clinical Investigation | 2008

Renin-angiotensin system gene polymorphisms and diastolic heart failure

Cho-Kai Wu; Chia-Ti Tsai; Juey-Jen Hwang; Jing-Ling Luo; Jyh-Ming Juang; Kwan-Lih Hsu; Ling-Ping Lai; J.-L. Lin; Chuen-Den Tseng; Fu-Tien Chiang

Background  Diastolic heart failure (DHF) refers to an abnormality of diastolic distensibility, filling or relaxation of the left ventricle. The genetic study of DHF is scarce in the literature. The association of renin‐angiotensin system (RAS) and DHF are well known. We hypothesized that RAS genes might be the susceptible genes for DHF and conducted a case‐control study to prove the hypothesis.


Journal of Internal Medicine | 2015

Statin use reduces the risk of dementia in elderly patients: a nationwide data survey and propensity analysis

Cho-Kai Wu; Yao-Hsu Yang; Ting-Tse Lin; Chia-Ti Tsai; Juey-Jen Hwang; J.-L. Lin; Pau-Chung Chen; Fu-Tien Chiang; Lian-Yu Lin

The objective of this study was to examine the association between the use of statins and the risk of newly diagnosed dementia in an elderly population.


The Cardiology | 2010

Association between Genetic Polymorphisms in the Renin-Angiotensin System and Systolic Heart Failure Revised by a Propensity Score-Based Analysis

Sheng-Nan Chang; J.-L. Lin; Jyh-Ming Juang; Chai-Ti Tsai; Juey-Jen Hwang; Fu-Tien Chiang

Objectives: The objective of this study is to identify possible genetic polymorphisms of the renin-angiotensin system (RAS) in systolic heart failure (sHF). Methods: A total of 509 patients were enrolled into this study. A non-parsimonious multivariable logistic regression model that incorporated potential risk factors was applied to calculate the propensity score for developing sHF. A 1:1 case-control selection process was made according to the rank of propensity. The six genetic polymorphisms of angiotensinogen (AGT), including T174M, M235T, G-6A, A-20C, G-152A, and G-217A, and angiotensin-converting enzyme (ACE) gene I/D polymorphism were typed by polymerase chain reaction and DNA sequencing technique. Results: The CC genotype at T174M was positively associated with sHF (OR 2.81, 95% CI 1.20–6.61, p = 0.018). The GG genotype at G-152A was also positively associated with the presence of sHF (OR 6.25, 95% CI 1.54–25.4, p = 0.010). OR of the ACE DD genotype for sHF, as compared with ACE II genotype, was 1.37 (p = 0.475), and OR for ID genotype compared with II genotype was 5.95 for sHF (95% CI 2.16–16.4, p = 0.001). Conclusions: The exploration of these RAS genes related to sHF may provide a more targeted and tailored treatment of sHF.


Journal of Internal Medicine | 2012

A functional variant in the promoter region regulates the C‐reactive protein gene and is a potential candidate for increased risk of atrial fibrillation

Sheng-Nan Chang; Chia-Ti Tsai; Cho-Kai Wu; Jen-Kuang Lee; Ling-Ping Lai; S.-W. Huang; Li Ying Huang; Chuen-Den Tseng; J.-L. Lin; Fu-Tien Chiang; Juey-Jen Hwang

Abstract.  Chang S‐N, Tsai C‐T, Wu C‐K, Lee J‐K, Lai L‐P, Huang S‐W, Huang L‐Y, Tseng C‐D, Lin J‐L, Chiang F‐T, Hwang J‐J (National Taiwan University Hospital Yun‐Lin Branch, Yun‐Lin; National Taiwan University Hospital, Taipei; National Taiwan University Hospital, Taipei; Institute of Pharmacology, Taipei; and Graduate Institute of Biomedical Engineering, Taipei, Taiwan). A functional variant in the promoter region regulates the C‐reactive protein gene and is a potential candidate for increased risk of atrial fibrillation. J Intern Med 2012; 272: 305–315.


Heart | 1998

New electrocardiographic criteria for the differentiation between counterclockwise and clockwise atrial flutter: correlation with electrophysiological study and radiofrequency catheter ablation

Ling-Ping Lai; J.-L. Lin; Li-Jen Lin; Wen-Jone Chen; Yi-Lun Ho; Yung-Zu Tseng; Chien-Lung Chen; Lee Yt; Lien Wp; Shoei K. Stephen Huang

Objective To develop new electrocardiographic (ECG) criteria for the differentiation between counterclockwise and clockwise atrial flutters. Background Traditionally, the ECG differentiation between counterclockwise and clockwise atrial flutters is based on the flutter wave polarity in the inferior leads. However, determination of flutter wave polarity is subjective and sometimes difficult, especially in flutter waves of undulating pattern. Patients The study comprised 37 consecutive patients with drug resistant atrial flutter; 30 had counterclockwise and 17 had clockwise atrial flutter (10 had both forms of atrial flutter). The isthmus dependence was confirmed by entrainment study and catheter ablation. The ECG patterns of both types of atrial flutter were compared and the flutter wave polarity in the inferior leads was determined by four independent cardiologists. Results The flutter wave polarity in the inferior leads appeared negative in 24, positive in one, and equivocal in five of the counterclockwise atrial flutters; polarity appeared negative in one, positive in 10, and equivocal in six of the clockwise atrial flutters. However, the aVF/lead I flutter wave amplitude ratio was > 2.5 in all counterclockwise but < 2.5 in all clockwise atrial flutters. The flutter wave nadirs in the inferior leads corresponded to the upstrokes in V1 in all counterclockwise atrial flutters, but corresponded to the downstrokes in V1 in all clockwise atrial flutters. Conclusions The flutter wave polarity in the inferior leads does not correlate well with the flutter wave rotating direction. However, counterclockwise and clockwise atrial flutters can be differentiated by new ECG criteria with high accuracy.


European Heart Journal | 1997

Electrophysiological properties in patients undergoing atrial compartment operation for chronic atrial fibrillation with mitral valve disease

Huey-Ming Lo; Fang-Yue Lin; J.-L. Lin; Chuen-Den Tseng; Kwan-Lih Hsu; Fu-Tien Chiang; Yung-Zu Tseng


Acta Cardiologica Sinica | 2000

A study on two kinds of human minK proteins: Electrophysiological and pharmacological properties and incidence in the Chinese population

Lin-Ping Lai; Ming-Jai Su; J.-L. Lin; Juey-Jen Hwang; Yung-Zu Tseng; Lien Wp; Shu-Wei Huang


Archive | 2000

Impact of dual site pacing on the natural history of symptomatic atrial fibrillation recurrence in patients without bradycardia

Hung-Fat Tse; Chu-Pak Lau; Cm Yu; Ws Teo; R Kam; Kh Ng; Sks Huang; J.-L. Lin; Sk Leung; Vyc Tsang; M Hill; S Fitts


Archive | 2000

Effect of dual site right atrial pacing on burden of atrial fibrillation in patients with drug-refractory atrial fibrillation

Cp Lau; Hf Tse; Cm Yu; Ws Teo; R Kam; Kh Ng; Sks Huang; J.-L. Lin; Sk Leung; Vyc Tsang; M Hill; S Fitts


Journal of The Formosan Medical Association | 1992

Inheritance of hypertrophic cardiomyopathy in Chinese--M-mode and two-dimensional echocardiographic analysis of 28 families.

Ko Yl; Meng-Huan Lei; Jun-Jack Cheng; J.-L. Lin; Chen Jj; Peiliang Kuan; Lien Wp

Collaboration


Dive into the J.-L. Lin's collaboration.

Top Co-Authors

Avatar

Juey-Jen Hwang

National Taiwan University

View shared research outputs
Top Co-Authors

Avatar

Ling-Ping Lai

National Taiwan University

View shared research outputs
Top Co-Authors

Avatar

Fu-Tien Chiang

National Taiwan University

View shared research outputs
Top Co-Authors

Avatar

Lien Wp

National Taiwan University

View shared research outputs
Top Co-Authors

Avatar

Cho-Kai Wu

National Taiwan University

View shared research outputs
Top Co-Authors

Avatar

Chia-Ti Tsai

National Taiwan University

View shared research outputs
Top Co-Authors

Avatar

Chuen-Den Tseng

National Taiwan University

View shared research outputs
Top Co-Authors

Avatar

Jyh-Ming Juang

National Taiwan University

View shared research outputs
Top Co-Authors

Avatar

Lian-Yu Lin

National Taiwan University

View shared research outputs
Top Co-Authors

Avatar

Yung-Zu Tseng

National Taiwan University

View shared research outputs
Researchain Logo
Decentralizing Knowledge