J. M. Crismon

Electrolyte, Water and Glycogen in Rat Muscle Following Ligation of Major Arteries and Veins.

Summary Ligation of the femoral artery (Series I), the common iliac artery and vein (Series II) or the femoral, popliteal and saphenous arteries and veins (Series III) in albino rats resulted in only slight alteration in the sodium, potassium and water content of the gastrocnemius and anterior tibial muscles 4 days after occlusion. Muscle glycogen was reduced in 2 out of 4 animals in Series I. Edema occurred in 1 animal in Series III, but the extra sodium found in the muscle could be accounted for by the increase in extracellular fluid. No gangrene or permanent functional changes were observed.