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Featured researches published by J.M. Edwards.


Phytochemistry | 1974

Phenalenone pigments of the root system of Lachnanthes tinctoria

J.M. Edwards; Ulrich Weiss

Abstract The root system of Lachnanthes tinctoria (Haemodoraceae) contains lachnanthoside, a glycoside of trihydroxy-9-phenylphenalenone; lachnanthofluorone, a red-fluorescent compound having a novel naphthoxanthenone structure; and a naphthalide related to the phenalenones.


Phytochemistry | 1976

Phenalenone pigments of the flowers of Lachnanthes tinctoria

Anthony C. Bazan; J.M. Edwards

Abstract Two new pigments have been isolated from flowers of Lachnanthes tinctoria . N -(1-carboxy-2-methylbutyl)-lachnanthopyridone is an oxygenated 9-ph


Phytochemistry | 1975

The sequential appearance and metabolism of alkaloids in Heimia salicifolia

R.H. Dobberstein; J.M. Edwards; A.E. Schwarting

Abstract The seeds of Heimia salicifolia do not contain alkaloids. Two unidentified alkaloids were detected in 1-week-old seedlings; these alkaloids were absent from older plant samples. Lyfoline, cryogenine, and lythrine were first detected in 2-week-old plants. Sinicuichine was first observed in 3-week-old plants and nesodine in 2-month-old plants. The maximum rates of synthesis for most of these alkaloids occurred in 1- to 2-month-old plants. Following administration of 14 CO 2 to H. salicifolia plants, small quantities of alkaloids were purified to constant specific activity without alkaloid dilution; 95.6% of the administered 14 CO 2 was assimilated and up to 0.16% of this activity was incorporated into known alkaloids. Sinicuichine and lyfoline were shown to undergo catabolism, while cryogenine was degraded very slowly, if at all. Evidence is presented for the conversion of lyfoline to lythrine.


Tetrahedron | 1978

Synthesis of lachananthocarpone [9-phenyl-2,6-dihydroxyphenalen-1(6)-one] by intramolecular diels-alder cyclization of a 1,7-diarylheptanoid orthoquino

A.C. Bazan; J.M. Edwards; U. Weiss


Tetrahedron Letters | 1972

Quinone methides derived from 5-oxa and 5-aza-9-phenyl-1-phenalenone in the flowers of lachnanthes tinctoria (haemodoraceae).☆

J.M. Edwards; Ulrich Weiss


Tetrahedron Letters | 1977

The biosynthesis of 2,5,6-trihydroxy-9-phenylphenalenone by Lachnanthes tinctoria. Incorporation of 1-13C-phenylalanine☆

Alan D. Harmon; J.M. Edwards; R.J Highet


ChemInform | 1979

SYNTHESIS OF LACHNANTHOCARPONE (9-PHENYL-2,6-DIHYDROXYPHENALEN-1(6)-ONE) BY INTRAMOLECULAR DIELS-ALDER CYCLIZATION OF A 1,7-DIARYLHEPTANOID ORTHOQUINONE: POSSIBLE BIOSYNTHETIC SIGNIFICANCE OF DIELS-ALDER REACTIONS

A. C. Bazan; J.M. Edwards; Ulrich Weiss


Tetrahedron Letters | 1977

Synthesis of lachnanthocarpone [9-phenyl-2,6-dihydroxyphenalen-1(6)-one] by intramolecular Diels-Alder cyclization of a 1,7-diarylheptadienoid orthoquinone.

A.C. Bazan; J.M. Edwards; Ulrich Weiss


Canadian Journal of Chemistry | 1970

Oxidation products of 2,3,6,7-tetramethoxy-9,10-dimethylphenanthrene

J.M. Edwards; Ulrich Weiss


ChemInform | 1970

OXIDATIONSPRODUKTE VON 2,3,6,7-TETRAMETHOXY-9,10-DIMETHYL-PHENANTHREN

J.M. Edwards; Ulrich Weiss

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Ulrich Weiss

National Institutes of Health

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A.C. Bazan

University of Connecticut

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A.E. Schwarting

University of Connecticut

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Alan D. Harmon

University of Connecticut

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