J.M.G Williams

Problem Solving Deteriorates Following Mood Challenge in Formerly Depressed Patients With a History of Suicidal Ideation.

The authors divided 34 participants who had a history of depression into 2 groups, those having previous suicidal ideation or behavior (n=19) and those having no such symptoms (n=15), then compared the 2 groups with a group of participants who had no history of depression (n=22). Assessment of interpersonal problem-solving performance using the Means-Ends Problem-Solving (MEPS) task before and after a mood-induction procedure showed that only those formerly depressed people with a history of suicidal ideation shifted in MEPS performance, producing significantly less effective problem solutions following mood challenge, consistent with a differential activation account of vulnerability for recurrence of suicidal ideation and behavior. The deterioration in effectiveness following mood challenge was moderated by lack of specificity in autobiographical memory.

Reduced autobiographical memory specificity and affect regulation.

The effect of specificity of autobiographical memory (AM) retrieval on the affective impact of an emotional event was examined. In Study 1 (N = 90) the impact of a negative and positive experience was compared between student participants who habitually retrieve autobiographical memories (AMs) in a specific way and participants who generally retrieve less specific memories. In Study 2 (N = 48) the effect of an experimentally induced (specific vs. overgeneral) retrieval style on the impact of a negative experience was studied in student participants who habitually retrieve less specific memories. Study 1 replicated the finding of Raes, Hermans, de Decker, Eelen, & Williams (2003) that a negative event leads to less subjective distress in low‐specific participants as compared with high‐specific participants. However, both groups did not differ in their affective reaction to a positive event. Important, reduced memory specificity was associated with “repressive coping”, providing further evidence for the idea that reduced memory specificity is used as an avoidant or repressive‐defensive mechanism to regulate negative affect (Williams, 1996). In Study 2, participants who were induced to retrieve memories in an overgeneral way experienced more distress following a negative event as compared with participants who were induced to retrieve memories in a specific way. Results are discussed in the context of recent findings concerning AM specificity and emotion regulation (Philippot, Schaefer, & Herbette, 2003). Directions for further research are suggested.

Effects of meditation on frontal alpha-asymmetry in previously suicidal individuals.

This study investigated the effects of a meditation-based treatment for preventing relapse to depression, mindfulness-based cognitive therapy (MBCT), on prefrontal &agr;-asymmetry in resting electroencephalogram (EEG), a biological indicator of affective style. Twenty-two individuals with a previous history of suicidal depression were randomly assigned to either MBCT (N=10) or treatment-as-usual (TAU, N=12). Resting electroencephalogram was measured before and after an 8-week course of treatment. The TAU group showed a significant deterioration toward decreased relative left-frontal activation, indexing decreases in positive affective style, while there was no significant change in the MBCT group. The findings suggest that MBCT can help individuals at high risk for suicidal depression to retain a balanced pattern of baseline emotion-related brain activation.

Retrieval of autobiographical memories: The mechanisms and consequences of truncated search

Five studies examined the extent to which autobiographical memory retrieval is hierarchical, whether a hierarchical search depends on central executive resources, and whether retrieving memories that are “higher” in the hierarchy impairs problem‐solving ability. The first study found that random generation (assessed using a button‐pressing task) was sensitive to changes in memory load (digit span). The second study showed that when participants fail to retrieve a target event, they respond with a memory that is higher up the hierarchy. The third study showed that memory is more generic only when participants use low imageable cues under cognitive load. The final two experiments showed that experimental manipulation of memory specificity affects problem solving (MEPS performance). The data are consistent with Conway and Pleydell‐Pearces hierarchical retrieval model of autobiographical memory, and suggest that overgeneral memory in nonclinical participants is associated with reduced executive capacity only when retrieval is “top‐down” (generative).

Dysfunctional beliefs in bipolar disorder: hypomanic vs. depressive attitudes.

BACKGROUND To date the effect of cognitive behavioural therapy modified for bipolar disorder has been inconsistent and sometimes disappointing. However studies exploring cognitive style in bipolar disorder have not identified the unique patterns of beliefs specific to bipolar disorder. The current study examines whether Mansells hypomania-related dysfunctional belief scale specifically identifies bipolar disorder patients. METHOD Forty remitted bipolar patients, twenty remitted unipolar patients and twenty healthy controls completed the Hypomanic Attitudes and Positive Prediction Inventory (HAPPI) and the Dysfunctional Attitude Scale (DAS). RESULTS The remitted bipolar group scored higher than the unipolar and healthy control groups on the HAPPI scale overall score and on three subscales that measured self-catastrophic beliefs, beliefs related to negative responses from other people when in elevated mood and beliefs related the response style to activation and elevation. CONCLUSION The study finds evidence of unique dysfunctional beliefs elevated only in remitted bipolar patients. Such findings could be used to inform the development of a specific cognitive behavioural therapy for bipolar disorder.

Relationship between cognitive avoidant coping and changes in overgeneral autobiographical memory retrieval following an acute stressor

According to the functional avoidance hypothesis, overgeneral autobiographical memory, the tendency to retrieve personal memories in a less specific format, might serve an affect-regulating function. Reducing the specificity of memories of negative events may prevent individuals from re-experiencing the associated painful emotions. This cognitive avoidance strategy might not only be employed by depressed and traumatized patients, but also by healthy individuals. In the present study we tested the hypothesis that the increase in memory overgenerality induced by an acute stressor is positively correlated with habitual (cognitive) avoidant coping. Participants (N = 32) were exposed to a Trier Social Stress Test. Cognitive avoidant coping was measured at the start of the experiment by means of the Mainz Coping Inventory. Before, immediately after, and 40 min after the Trier Social Stress Test, autobiographical memory specificity was assessed by means of the Autobiographical Memory Test. Cognitive avoidant coping was significantly correlated with an increase in categoric memories from pre to immediately post stressor, but not with change in overgeneral memories from pre to 40 min post stressor. The results of the present experiment provide further support for functional avoidance as one of the mechanisms underlying overgeneral memory.

Self-discrepancy in students with bipolar disorder II or NOS

BACKGROUND Studies on self-representation in bipolar disorder have mainly focused on the single dimension of self-esteem and recruited patients either in episode or in remission. The aim of the study was to examine multi-dimensional aspects of the self (discrepancy between actual- and ideal-selves and between actual- and feared-selves) in a student sample with a history of significant experience of hypomania (with or without experience of major depression) as compared to healthy control students. METHODS Bipolar students and healthy control students completed the Self-Discrepancy Questionnaire (SDQ: Carver, Lawrence, & Scheier, 1999). The degree of similarity to, and the perceived likelihood of ideal-self and feared-self characteristics were assessed. RESULTS The difference between the groups in level of ideal-self similarity was at trend level. Students with prior hypomania but no history of depression showed higher similarity to their feared-self than healthy controls and also rated themselves as more likely to have these feared-self characteristics in the future. LIMITATION The small sample size, especially in the bipolar group with no history of depression, limits the power of the study. CONCLUSIONS The presence of ideal-self discrepancy was not convincingly demonstrated in this sample and it is possible that where it has been identified in previous studies it may, at least in part, represent a scar of previous episodes of depression or mania rather than a predisposing factor. However a sub-sample of students who had experienced hypomania in the absence of history of depression were distinguished from healthy controls in perceived closeness to the feared-self qualities. The feared-self concept warrants further investigation in bipolar patients.

Self-Organization in Bipolar Disorder: Replication of Compartmentalization and Self-Complexity

Remitted bipolar patients were compared to remitted unipolar patients and healthy controls on a self concept task assessing degree of self-compartmentalization (clustering of self-aspects based on valence) and self-complexity (the degree of relatedness versus differentiation across self-aspects). Similar to the findings of Taylor et al. (Cognitive Therapy and Research, 31(1), 83-96, 2007) the bipolar and unipolar groups showed higher levels of self compartmentalization than healthy controls. No differences were found on the self complexity measure.

Operant conditioning of autobiographical memory retrieval

Functional avoidance is considered as one of the key mechanisms underlying overgeneral autobiographical memory (OGM). According to this view OGM is regarded as a learned cognitive avoidance strategy, based on principles of operant conditioning; i.e., individuals learn to avoid the emotionally painful consequences associated with the retrieval of specific negative memories. The aim of the present study was to test one of the basic assumptions of the functional avoidance account, namely that autobiographical memory retrieval can be brought under operant control. Here 41 students were instructed to retrieve personal memories in response to 60 emotional cue words. Depending on the condition, they were punished with an aversive sound for the retrieval of specific or nonspecific memories in an operant conditioning procedure. Analyzes showed that the course of memory specificity significantly differed between conditions. After the procedure participants punished for nonspecific memories retrieved significantly more specific memories compared to participants punished for specific memories. However, whereas memory specificity significantly increased in participants punished for specific memories, it did not significantly decrease in participants punished for nonspecific memories. Thus, while our findings indicate that autobiographical memory retrieval can be brought under operant control, they do not support a functional avoidance view on OGM.