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The Lancet | 1975

ABNORMAL LEUCOCYTE COMPOSITION AND SODIUM TRANSPORT IN ESSENTIAL HYPERTENSION

R. P. S. Edmondson; Philip J. Hilton; R.D. Thomas; J. Patrick; N.F. Jones

Cation transport and electrolyte composition were studied in leucocytes from 17 patients with uncomplicated essential hypertension. Significant increases in cell sodium and water contents, associated with a depression of the rate-constant for active sodium efflux, were found in the hypertensive patients. These abnormalities in cell sodium transport may possibly be related to mechanisms of hypertension.


Clinical Science | 1973

Sodium and Potassium Flux Rates in Normal Human Leucocytes in an Artificial Extracellular Fluid

P. J. Hilton; J. Patrick


Clinical Science | 1975

Leucocyte sodium transport in uraemia.

R. P. S. Edmondson; P. J. Hilton; N.F. Jones; J. Patrick; R.D. Thomas


The Lancet | 1974

LEUCOCYTE ELECTROLYTES IN CARDIAC AND NON-CARDIAC PATIENTS RECEIVING DIURETICS

R. P. S. Edmondson; Philip J. Hilton; R.D. Thomas; J. Patrick; N.F. Jones


Clinical Science | 1978

Effect of zinc on leucocyte sodium transport in vitro.

J. Patrick; J. Michael; M. N. Golden; B. E. Golden; P. J. Hilton


Clinical Science | 1974

CELL SODIUM, POTASSIUM AND WATER IN URAEMIA AND THE EFFECTS OF REGULAR DIALYSIS AS STUDIED IN THE LEUCOCYTE

J. Patrick; N.F. Jones


Clinical Science | 1980

Zinc Transport in Normal Human Leucocytes: Dependence upon Media Composition

R. B. Jones; P. J. Hilton; J. Michael; J. Patrick; Valerie E. Johnson


Clinical Science | 1981

Increased sodium content and altered sodium transport in thymocytes of spontaneously hypertensive rats.

R. B. Jones; J. Patrick; P. J. Hilton


Journal of Cellular Physiology | 1981

The effects of alterations in the external sodium concentration on human leucocyte sodium and potassium transport in vitro

P. J. Hilton; Valerie E. Johnson; R. B. Jones; J. Patrick


Clinical Science | 1974

SODIUM AND POTASSIUM TRANSPORT RATES IN NORMAL HUMAN LEUCOCYTES IN HYPO-OSMOLAL EXTRACELLULAR FLUID

P. J. Hilton; J. Patrick

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