J Reimer Wolter

Cell life on the surface of lens implants

A simple technique called lens implant cytology is used to demonstrate cellular membranes on three plastic intraocular lenses removed at about 1, 2 and 3 years after implantation. The pattern of the reactive process somewhat resembles a special foreign body reaction. The cells living on the lens surface have successfully formed a separating membrane between implants and the remainder of the eye in all three cases.ZusammenfassungEine einfache Methode, Linsenimplant Zytologie genannt, wurde benutzt, um zellige Membranen auf drei Plastiklinsen darzustellen, die 1, 2 und 3 Jahre nach Einpflanzung entfernt wurden. Der beobachtete reaktive Prozeß ist einer besonderen Fremdkörperreaktion ähnlich. Die Zellen auf der Linsenoberfläche haben in alien drei Fällen mit Erfolg eine trennende Schicht zwischen Plastiklinse und innerem Auge geschaffen.

Pigment in Cellular Membranes on Intraocular Lens Implants

Cells with protoplasmic pigment granules on the surface of intraocular lens implants can be divided by their basic nature into histiocytes, epitheloid cells, giant cells, small fibroblast-like cells, iris melanocytes, pigment epithelium, and probably corneal endothelium. All these cells are part of a cellular membranes that have been observed on lens implants at times between eight months and three and a half years after lens implantation.

Foveal Pathology in Ciliary Body Melanoma

The histological features of cystoid macular edema in an early stage are demonstrated in the eye of a 54-year-old patient with an active ciliary body melanoma. Separation of the posterior vitreous face and the inner limiting membrane with accumulation of an exudate in the resulting space, petaloid folding of the inner retinal layers, swelling as well as microcystoid degeneration of Henles fiber layer, and vertical folding of the outer retinal layers with separation of the central cones from the pigment epithelium are observed.

Leaky Cystoid Macular Edema Attracting Vitreous Macrophages

A foveola with signs of atrophy and cystoid edema in an eye with a history of contusion, laceration, and hemorrhage exhibits a selective attraction of blood-filled macrophages. This important observation allows for the conclusion that the avascular foveola can leak into the inner eye like a blood vessel and chemotactically attract vitreous macrophages under these conditions.

Foveal Pathology Following Anterior Segment Injury

A case of traumatic ocular perforation and aphakia resulting in enucleation after six weeks is used to demonstrate histopathological details of an early stage of a typical foveal involvement with grossly visible petaloid swelling of the central retina, separation of the inner limiting membrane with some exudate, massive swelling and early cystoid degeneration of Henles fiber layer and a vertical retinal fold of the outer retinal layers extending downward from the foveola. This demonstration is important in view of its possible relationship to the clinical entity of cystoid macular edema.

Vertical folds of central retinal and choroid in sudden ocular decompression.

Sudden and limited decompression of an eye due to corneal rupture has four days later allowed for the histopathological demonstration of an interesting combination of a vertical retinal fold, cystoid macular edema, degeneration of foveal cones, a vertical choroidal fold with loss of pigment epithelium and papilledema. The rather bizarre changes in this case may be helpful for the understanding of the much more subtle histopathological findings in typical cystoid macular edema.