J.W. Krotec

P-13: The Effect of Endometriosis on Pregnancy Outcome Following In Vitro Fertilization-Embryo Transfer (IVF-ET) in Women With Decreased EGG Reserve

PURPOSE To determine the effect of the presence of endometriosis on the delivered pregnancy rate following in vitro fertilization-embryo transfer. METHODS A retrospective cohort analysis of fresh or frozen embryo transfer in women with diminished egg reserve having IVF-ET and who also had had a laparoscopy. The data was analyzed as to whether endometriosis was present or not. RESULTS The data demonstrated that women with diminished egg reserve can achieve pregnancies following IVF-ET. The presence of endometriosis did not have any negative effects on pregnancy rates. CONCLUSIONS At least in women with diminished egg reserve the presence of endometriosis did not impair outcome following IVF-ET.

AbstractPoster presentationP-14: Relationship of Serum Progesterone (P) Level the Day After Human Chorionic Gonadotropin (hCG) Injection on Outcome Following In Vitro Fertilization-Embryo Transfer (IVF-ET)

PURPOSE To determine if either too little or too much of a rise in serum progesterone (P) on the day after human chorionic gonadotropin (hCG) injection has any negative impact on pregnancy outcome following in vitro fertilization-embryo transfer (IVF-ET). METHODS Retrospective review. Three progesterone groups established--low, normal and high. RESULTS There was a significantly higher clinical pregnancy rate in the normal P group vs low or high. There were no significant differences in ongoing delivered pregnancy rates but a trend for higher implantation rates in the normal P group. CONCLUSIONS These data are consistent with the hypothesis that either too little or too much P can adversely effect implantation. However, the differences are not of sufficient magnitude to warrant a clinical intervention, e.g., deferring fresh transfer and freezing the embryos for future transfer.