J. William Hinton

The Effect of Morphine, Demerol and Codeine on Serum Amylase Values in Man

Summary Neither morphine, Demerol or codeine causes elevated serum amylase values unless the pancreas is secreting when the analgesic is given. Such conditions exist in a patient up to 4 hours after a meal or with acute primary or secondary inflammation of the pancreas. Thus the interpretation applied to a serum amylase value need not be altered because an analgesic has been used.

Follow-up results in sub-total gastric resection for ulcer

Association, June 8, 1942, Atlantic City, New Jersey. A statistical analysis of 104 sub-total gastric resections for peptic ulcers together with their end results, is presented. Post-operative symptoms do not appear to bear any direct relationship to post-operative complications. Failure to resect an adequate amount of stomach and to remove the ulcer crater is the most common cause for recurrence. Marginal ulcers are not to be feared as a post-operative complication provided sufficient stomach tissue is removed and the ulcer is always removed in toto.

The incidence of gastro-jejunal ulcer following gastroenterostomy

The above cases have been presented in detail so as to give a complete clinical picture of each case and one can note that of the 13 cases we are reporting, five were operated upon in hospitals in or around New York and eight were operated upon at Bellevue Hospital, and of the 13 cases no two patients were operated upon by the same surgeon. From the review of our cases we feel that any conclusions drawn as to the percentage of gastro-jejunal ulcers developing after gastroenterostomy is most inaccurate unless the patient has been followed for a 10-year period, and also seen at frequent intervals, with repeated X-ray examinations. A follow-up letter in stomach cases is not only inaccurate but misleading and instead of being a help usually presents false information. It is seen that three of our cases that came to operation developed their symptoms of a marginal ulcer after seven years, one being ten and a half years following gastroenterostomy.