Jae Hoon Cheong
Pusan National University
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Publication
Featured researches published by Jae Hoon Cheong.
Journal of Gastroenterology and Hepatology | 2011
Sung Han Park; Gwang Ha Kim; Do Youn Park; Na Ri Shin; Jae Hoon Cheong; Ji Yoon Moon; Bong Eun Lee; Geun Am Song; Hyung-Il Seo; Tae Yong Jeon
Background and Aim: Ectopic pancreas is a common submucosal lesion in the stomach, but its histological diagnosis is usually difficult when tissue samples are obtained with a conventional biopsy forceps. The aim of this study was to describe the endosonographic features of gastric ectopic pancreas.
Scandinavian Journal of Gastroenterology | 2011
Dong Uk Kim; Gwang Ha Kim; Dong Yup Ryu; Dong Gun Lee; Jae Hoon Cheong; Bong Eun Lee; Geun Am Song; Do Youn Park; Na Ri Shin; Hoseok I; Mitsuhiro Kida
Abstract Objective. Submucosal tumors (SMTs) are occasionally found in the esophagus during upper endoscopy. Granular cell tumors (GCTs) are reported to be the second most common esophageal mesenchymal tumors, after leiomyomas. Endoscopic ultrasonography (EUS) is an effective tool for predicting the histologic characteristics of SMTs by providing an accurate image of the layering structure of the esophagus, but it is hard to differentiate GCTs from submucosal leiomyomas accurately with conventional EUS. The aim of the present study was to characterize the EUS features of GCTs compared with those of submucosal leiomyomas using a high-frequency catheter probe EUS. Material and methods. A total of 41 patients with GCTs or submucosal leiomyomas were included. All of the patients underwent EUS before histologic confirmation by endoscopic resection or biopsy. Results. There were 14 GCTs in 12 patients and 30 leiomyomas in 29 patients. GCTs had a white-to-yellow surface color more frequently than leiomyomas. In comparison with the surrounding normal proper muscle layer, the echogenicity of the leiomyomas was similar to that of the surrounding muscle layer, but more than half of the GCTs were hyperechoic compared to the surrounding muscle layer. Unclear borders were observed more frequently in GCTs than in leiomyomas. The presence of at least two of these three features in a given tumor had a sensitivity of 85.7%, a specificity of 96.7%, and an accuracy of 93.2% for predicting GCTs. Conclusions. High-frequency probe EUS is helpful for differentiating esophageal GCTs from submucosal leiomyomas.
Scandinavian Journal of Gastroenterology | 2011
Jae Hoon Cheong; Gwang Ha Kim; Bong Eun Lee; Moon Ki Choi; Ji Yoon Moon; Dong Yup Ryu; Dong Uk Kim; Geun Am Song
Abstract Objective. Limited information is available on predictors of the response to proton pump inhibitor (PPI) treatment in patients with gastroesophageal reflux disease (GERD). Endoscopic grading of gastroesophageal flap valve (GEFV) is simple and reproducible, and can provide useful information on patients with suspected reflux undergoing an endoscopy. The aim of this study was to prospectively identify predictors, including endoscopic findings such as GEFV, for PPI treatment outcomes in patients with GERD. Material and methods. One hundred and fifty consecutive patients with GERD were enrolled. All patients were treated with pantoprazole 40 mg daily for 8 weeks. Treatment response was defined as greater than 50% reduction in symptom scores between the two symptom assessments (i.e., over 4 or 8 weeks). Univariate and multivariate logistic regression analyses between responders and non-responders were performed to identify variables predicting response to pantoprazole treatment. Results. Of the 150 consecutive patients considered for this study, 31 were excluded based on exclusion criteria and/or refusal to participate, leaving 119 eligible patients. After 4-week pantoprazole treatment, 70 of 119 (58.8%) patients were classified as responders. Patients with obesity and Helicobacter pylori infection demonstrated a higher response rate to 4-week pantoprazole treatment (odds ratio (OR) 5.28, p = 0.008; OR 3.76, p = 0.023, respectively). Patients with abnormal GEFV showed a lower response rate to 4-week treatment (OR 0.17, p = 0.016). After 8-week treatment, 86 of 119 (72.3%) patients were classified as responders. Abnormal GEFV and aspirin intake were associated with a lower response rate to 8-week treatment (OR 0.17, p = 0.021; OR 0.11, p = 0.020, respectively). Conclusions. Abnormal GEFV was a significant independent factor predicting poor response to both 4-week and 8-week pantoprazole treatment. Endoscopic grading of GEFV provides useful information for predicting the response to PPI treatment in patients with GERD.
Journal of Neurogastroenterology and Motility | 2013
Hye Kyung Jeon; Gwang Ha Kim; Mun Ki Choi; Jae Hoon Cheong; Dong Hoon Baek; Gwang Jae Lee; Hang Mi Lee; Bong Eun Lee; Geun Am Song
Background/Aims Globus is a persistent or intermittent non-painful sensation of a lump or foreign body in the throat. Given the benign nature of the condition and the association of gastroesophageal reflux disease, empirical therapy with proton pump inhibitor seems reasonable for patients with typical globus. The aim of this study was to investigate the clinical predictors for symptom response to short-term proton pump inhibitor treatment in patients with globus symptom. Methods Fifty-four patients with globus symptom were enrolled prospectively. All patients were treated with pantoprazole 40 mg daily for 4 weeks. Treatment response was defined as a > 50% reduction in symptom scores between symptom assessments. Univariate and multivariate logistic regression analysis between responders and non-responders was performed to identify variables predicting response to pantoprazole treatment. Results Of the 54 consecutive patients considered, 13 were excluded on the basis of exclusion criteria and/or refusal to participate in the study. Finally, 41 patients were included in this study. After 4-week pantoprazole treatment, 22 patients (53.7%) were classified as responders. On multivariate analysis, the presence of reflux symptom was associated with a higher response rate to 4-week pantoprazole treatment (OR, 68.56; P = 0.043), and long symptom duration (≥ 3 months) were associated with a lower response rate to pantoprazole treatment (OR, 0.03; P = 0.034). Conclusions Presence of reflux symptom and short symptom duration were independent predictors of responsiveness to 4-week pantoprazole treatment in patients with globus.
World Journal of Gastrointestinal Endoscopy | 2013
Jae Hoon Cheong; Gwang Ha Kim; Ji Yoon Moon; Bong Eun Lee; Dong Yup Ryu; Dong Uk Kim; Hyung-Il Seo; Geun Am Song
AIM To evaluate the efficacy of endoscopic ultrasonography (EUS) in patients with elevated carbohydrate antigen (CA) 19-9 levels of obscure origin. METHODS Patients who had visited Pusan National University Hospital because of elevated serum CA 19-9 levels, between January 2007 and December 2009, were retrospectively enrolled. EUS had been performed on all subjects, in addition to routine blood tests, endoscopy, abdominal computed tomography (CT) and other clinical exams, which had not revealed any abnormal findings suggestive of the origin of the elevated CA 19-9 levels. RESULTS Of the 17 patients, gallbladder sludge was detected in 16 patients (94.1%) and common bile duct sludge was observed in 3 patients (17.6%). After the administration of ursodeoxycholic acid to 12 of the patients with gallbladder sludge, CA 19-9 levels normalized in 6 of the patients after a median of 4.5 mo. CONCLUSION EUS is a useful diagnostic method for patients with elevated CA 19-9 levels of obscure origin, even if the reason for abnormal levels of this serum marker cannot be determined through prior examinations, including abdominal CT.
Surgical Endoscopy and Other Interventional Techniques | 2013
Mun Ki Choi; Gwang Ha Kim; Do Youn Park; Geun Am Song; Dong Uk Kim; Dong Yup Ryu; Bong Eun Lee; Jae Hoon Cheong; Mong Cho
The Korean Journal of Gastroenterology | 2012
Jae Hoon Jeong; Gwang Ha Kim; Geun Am Song; Dong Gun Lee; Ji Yoon Moon; Jae Hoon Cheong; Suk Kim
The Korean Journal of Gastroenterology | 2012
Ji Yoon Moon; Gwang Ha Kim; Jae Hoon Cheong; Bong Eun Lee; Dong Yup Ryu; Geun Am Song
The Korean journal of internal medicine | 2007
Seong Geun Lee; Jae Hoon Cheong; Ji Eun Kim; Heon Song; Seoung Jae An; Dong Won Lee; Bong Eun Lee; Ihm Soo Kwak
Gastrointestinal Endoscopy | 2011
Gwang Ha Kim; Bong Eun Lee; Jae Hoon Cheong; Dong Uk Kim; Seok-Reyol Choi; Do-Youn Park; Geun Am Song