Jae In Lee

A new convenient method for the esterification of carboxylic acids

Abstract Reaction of carboxylic acids with equimolar amounts of alkyl chloroformate and triethylamine in the presence of a catalytic amount of 4-dimethylaminopyridine affords the corresponding esters in high yields without the formation of the symmetrical anhydride in most carboxylic acids.

Reaction of lithium dialkylcuprates with S-2-pyridyl thioates in the presence of oxygen. A carboxylic ester synthesis

Reaction of lithium dialkylcuprates with S-2-pyridyl thioates in the presence of oxygen affords carboxylic esters in high yields, whereas under nitrogen it affords ketones.