Jaime A. Tschen

Molluscum Contagiosum of the Nipple-Areola Complex

Molluscum contagiosum is a skin lesion caused by a poxvirus that commonly affects young children or immunocompromised adults. Although cutaneous infection with molluscum contagiosum has been well described, occurrence in the nipple-areola complex is rare, and there is little data on the clinical presentation, disease course, and treatment methods of molluscum contagiosum lesions in these areas. This chapter reviews the characteristics of molluscum contagiosum and describes six cases of this viral infection occurring in the nipple-areola complex.

A Rare Variant of Penile Squamous Cell Carcinoma in a Man with Paraplegia

Verrucous carcinoma (VC) is a rare variant of squamous cell carcinoma (SCC). It is described as a low grade, slow growing, locally infiltrative neoplasm that accounts for 3%-8% of penile SCCs. Here we report a case of destructive VC of the glans penis in a paraplegic man resulting in a hypospadias from the tip of the glans to the corona. Histology demonstrated exophytic squamous epithelial proliferation with characteristic round, pushing borders. In situ hybridization was positive for both low-risk and high-risk strains of human papillomavirus.

The Development of Psoriasis Over a Silicone Granuloma: Case Report and Postulated Mechanism of Pathogenesis

Liquid silicone injections are used for soft tissue augmentation and have the potential to cause adverse effects. A 60-year-old woman who developed a psoriatic lesion over a silicone granuloma is reported. The clinical, dermatoscopic, and histological findings were characteristic of psoriasis. The patient was started on hydroxychloroquine for the treatment of the granuloma without any subsequent development of new psoriatic lesions. The presentation of psoriasis associated with a silicone granuloma in an immunocompetent patient is unique. The sequence of events is another example of a dermatosis occurring in an immunocompromised cutaneous district.