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Dive into the research topics where Jalal Uddin Bhat is active.

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Featured researches published by Jalal Uddin Bhat.


Excli Journal | 2012

Nephroprotective action of Peucedanum grande against cadmium chloride induced renal toxicity in Wistar rats

Mohammad Aslam; Shiekh Tanveer Ahmad; Rameshver Dayal; Kalim Javid; Sadiq Umar; Asia Asiaf; Sana Nafees; Jalal Uddin Bhat; Arjumand Wani; Mohammad Samim; Surender Singh

Cadmium is a known industrial pollutant which accumulates in the kidney and its exposure leads to the production of reactive oxygen species (ROS). The present study was carried out to evaluate the protective effects of Peucedanum grande against CdCl2 induced renal toxicity in Wistar rats. Wistar rats were subjected to oral pre-treatment of P. grande (60 and 120 mg/kg b.wt) against the renal toxicity induced by administration of CdCl2 (3mg/kg b.wt). Efficacy of P. grande against the renal toxicity was evaluated in terms of biochemical estimation of antioxidant enzyme activities and histopathological changes. P. grande pretreatment prevented deteriorative effects induced by CdCl2 through a protective mechanism that involved reduction of increased oxidative stress as well as by restoration of histopathological changes against CdCl2 administration.


Excli Journal | 2012

Anti-seizure activity of flower extracts of Nepeta bractaeta in Swiss albino mice

Mohd Aftab Ahmad; Shahid Ansari; Mohammad Aslam; Jalal Uddin Bhat; Razia Khanam; Qudsia Nizami; Shabir Ahmad Parray; Aisha Siddiqui

Epilepsy is a neurological disorder characterized by unprovoked, recurring seizures that disrupts the nervous system and can cause mental and physical dysfunction. Based on the ethno pharmacological information of the plant, the methanolic and aqueous extracts of the flowers of Nepeta bractaeta was evaluated for its antiepileptic activity. The methanolic and aqueous extracts of the flowers of Nepeta bracteata were observed for their antiepileptic activity by increased current Electroshock seizures (ICES) test and Pentylenetetrazole (PTZ) test using Swiss albino mice. Both the extracts showed significant activity in ICES and PTZ induced convulsions in comparison to control. In ICES model, NBAE at higher dose showed 16.7 % and NBME at higher dose showed 33.3 % protection against seizure and in PTZ model, NBME at higher dose showed 33.3 % protection against seizure. From the experiments performed, it can be said that Nepeta bractaeta does possess anticonvulsant property.


Excli Journal | 2012

Anticonvulsant activity of methanolic and aqueous extracts of Melissa parviflora in experimentally induced Swiss albino mice

Shiekh Tanveer Ahmad; Asia Asiaf; Mohammad Aslam; Jalal Uddin Bhat; Razia Khanam; Mohammad Mujeeb; Qudsia Nizami; Shabir Ahmad Parray; Aisha Siddiqui; Sadiq Umar

The aim of the present study was to evaluate the anticonvulsant effect of whole plant extracts of Melissa parviflora using MES and PTZ induced seizures models. The dried whole plant was subjected to extraction in methanol and water. The extracts were subjected to phytochemical tests and the carbohydrate, flavonols, coumarins, glycosides and steroid were found to be present. The methanolic and aqueous extracts of the plant of Melissa parviflora were observed for their anticonvulsant activity by Maximal Electroshock seizures (MES) test and Pentylenetetrazole (PTZ) test using Swiss albino mice. Both the extracts showed significant activity in MES and PTZ induced convulsions in comparison to control. From the literature surveys as well experiments performed, it can be said that Melissa parviflora does pose anticonvulsant property.


Archive | 2012

ANTICONVULSANT ACTIVITY OF METHANOLIC EXTRACT OF MELISSA PARVIFLORA IN EXPERIMENTALLY INDUCEDSWISS ALBINO MICE

Jalal Uddin Bhat; Qudsia Nizami; Mohammad Aslam; Shabir Ahmad Parray; Asia Asiaf; Mohammad Mujeeb


Journal of Natural Product and Plant Resources | 2013

Pharmacognostical and Phytochemical Evaluation of Melissa parvifloraandHPTLC fingerprinting of its extracts

Jalal Uddin Bhat; Qudsia Nizami; Shabir Ahmad Parray; Mohammad Aslam; Aisha Siddiqui; Nazeem Fahamiya; Mohammad Mujeeb; RaziaKhanam; Masood Shah Khan


Archive | 2012

Original article: ANTI-SEIZURE ACTIVITY OF FLOWER EXTRACTS OF NEPETA BRACTAETA IN SWISS ALBINO MICE

Jalal Uddin Bhat; Shabir Ahmad Parray; Mohammad Aslam; Shahid Ansari; Qudsia Nizami; Razia Khanam; Aisha Siddiqui; Mohd Aftab Ahmad


Archive | 2012

ANTIEPILEPTIC ACTIVITY OF THE WHOLE PLANT EXTRACTOF MELISSA OFFICINALIS IN SWISS ALBINO MICE

Jalal Uddin Bhat; Qudsia Nizami; Mohammad Aslam; Asia Asiaf; Shiekh Tanveer Ahmad; Shabir Ahmad


Archive | 2012

Original article: ANTICONVULSANT ACTIVITY OF METHANOLIC AND AQUEOUS EXTRACTS OF MELISSA PARVIFLORA IN EXPERIMENTALLY INDUCED SWISS ALBINO MICE

Jalal Uddin Bhat; Qudsia Nizami; Asia Asiaf; Shabir Ahmad Parray; Mohammad Aslam; Razia Khanam; Mohammad Mujeeb; Sadiq Umar; Aisha Siddiqui


Archive | 2012

Original article: NEPHROPROTECTIVE ACTION OF PEUCEDANUM GRANDE AGAINST CADMIUM CHLORIDE INDUCED RENAL TOXICITY IN WISTAR RATS

Mohammad Aslam; Shiekh Tanveer Ahmad; Rameshver Dayal; Kalim Javid; Sadiq Umar; Asia Asiaf; Sana Nafees; Jalal Uddin Bhat; Arjumand Wani; Mohammad Samim; Surender Singh; Ansari Nagar


Archive | 2012

A REVIEW OF ZUFAH-E-YABIS (NEPETA BRACTEATES) PHYTOCHEMICAL AND PHARMACOLOGICAL STUDIES

Jalal Uddin Bhat; Qudsia Nizami; Shabir Ahmad Parray; Mohd Aftab Ahmad; Mohd Aslam

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Razia Khanam

Gulf Medical University

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