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Dive into the research topics where James D. McChesney is active.

Publication


Featured researches published by James D. McChesney.


Journal of Chromatography B | 2003

Measurement of paclitaxel in biological matrices : high-throughput liquid chromatographic-tandem mass spectrometric quantification of paclitaxel and metabolites in human and dog plasma

Michael S. Alexander; Melissa M. Kiser; Travis Culley; John R Kern; John W. Dolan; James D. McChesney; Jan Zygmunt; Steve J. Bannister


Archive | 2001

Stable isotope labeling of paclitaxel

Michael S. Alexander; James D. McChesney; Jan Zygmunt


Archive | 1999

Alternate method for acylating 10-deacetylbaccatin iii selectively at the c-10 position

Nicholas J. Sisti; Jan Zygmunt; Herbert R. Brinkman; Madhavi C. Chander; Xian Liang; James D. McChesney


Archive | 1998

Method for selective acylation of C-2'-O-protected-10-hydroxy-taxol at the C-10 position

Xian Liang; Jan Zygmunt; Nicholas J. Sisti; Madhavi C. Chander; Herbert R. Brinkman; James D. McChesney


Archive | 1998

Method for conversion of C-2'-O-protected-10-hydroxy taxol to c-2'-O-protected taxol:useful intermediates in paclitaxel synthesis

Nicholas J. Sisti; Herbert R. Brinkman; James D. McChesney; Madhavi C. Chander; Xian Liang; Jan Zygmunt


Archive | 2002

Three-step conversion of protected taxane ester to paclitaxel

Jan Zygmunt; James D. McChesney


Archive | 1999

C-2 hydroxyl protected-N-acyl (2R,3S)-3-phenylisoserine N-imido activated esters and method for production thereof

Jan Zygmunt; James D. McChesney; Madhavi C. Chander


Archive | 1999

Methods and useful intermediates for paclitaxel synthesis from c-7, c-10 di-cbz baccatin iii

Nicholas J. Sisti; Herbert R. Brinkman; James D. McChesney; Madhavi C. Chander; Xian Liang; Jan Zygmunt


Archive | 1999

C-2 hydroxyl protected-n-acyl (2R,3S)-3-phenylisoserine substituted phenyl activated esters and method for production thereof

Madhavi C. Chander; James D. McChesney; Jan Zygmunt


Archive | 2001

Chiral resolution method for producing compounds useful in the synthesis of taxanes

James D. McChesney; Herbert R. Brinkman; Siead Zegar; David Baehr

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