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Featured researches published by James Knepler.


Annals of the American Thoracic Society | 2015

The Impact of a Comprehensive Airway Management Training Program for Pulmonary and Critical Care Medicine Fellows. A Three-Year Experience

Jarrod Mosier; Joshua Malo; John C. Sakles; Cameron Hypes; Bhupinder Natt; Linda Snyder; James Knepler; John W. Bloom; Raj Joshi; Kenneth S. Knox

RATIONALE Airway management in the intensive care unit (ICU) is challenging, as many patients have limited physiologic reserve and are at risk for clinical deterioration if the airway is not quickly secured. In academic medical centers, ICU intubations are often performed by trainees, making airway management education paramount for pulmonary and critical care trainees. OBJECTIVES To improve airway management education for our trainees, we developed a comprehensive training program including an 11-month simulation-based curriculum. The curriculum emphasizes recognition of and preparation for potentially difficult intubations and procedural skills to maximize patient safety and increase the likelihood of first-attempt success. METHODS Training is provided in small group sessions twice monthly using a high-fidelity simulation program under the guidance of a core group of two to three advanced providers. The curriculum is designed with progressively more difficult scenarios requiring critical planning and execution of airway management by the trainees. Trainees consider patient position, preoxygenation, optimization of hemodynamics, choice of induction agents, selection of appropriate devices for the scenario, anticipation of difficulties, back-up plans, and immediate postintubation management. Clinical performance is monitored through a continuous quality improvement program. MEASUREMENTS AND MAIN RESULTS Sixteen fellows have completed the program since July 1, 2013. In the 18 months since the start of the curriculum (July 1, 2013-December 31, 2014), first-attempt success has improved from 74% (358/487) to 82% (305/374) compared with the 18 months before implementation (P = 0.006). During that time there were no serious complications related to airway management. Desaturation rates decreased from 26 to 17% (P = 0.002). Other complication rates are low, including aspiration (2.1%), esophageal intubation (2.7%), dental trauma (0.8%), and hypotension (8.3%). First-attempt success in a 6-month period after implementation (July 1, 2014-December 31, 2014) was significantly higher (82.1 compared with 70.9%, P = 0.03) than during a similar 6-month period before implementation (July 1, 2012-December 31, 2012). CONCLUSIONS This comprehensive airway curriculum is associated with improved first-attempt success rate for intensive care unit intubations. Such a curriculum holds the potential to improve patient care.


Journal of bronchology & interventional pulmonology | 2010

The mean green popsicle: using cryotherapy to remove aspirated foreign bodies.

Joseph C. Seaman; James Knepler; Karen Bauer; Mitchell C. Rashkin

Foreign body (FB) aspiration can be a life-threatening event. Although more common in children, FB aspiration can occur at any age. Symptoms related to FB aspiration range from coughing and shortness of breath to asphyxiation. Chest imaging can be nonspecific and infrequently identifies an FB. Herein, we describe a case of a 54-year-old male patient who aspirated an FB and experienced respiratory arrest. He failed to improve with conservative measures and required emergent bronchoscopy. He was found to have an FB in his proximal left mainstem bronchus that could not be removed using standard bronchoscopy and he was referred to our center for definitive care. We used a cryotherapy probe to remove the FB. We propose that cryotherapy is a useful tool to remove FBs that are soft and amenable to freezing.


Southwest Journal of Pulmonary and Critical Care | 2018

Airway registry and training curriculum improve intubation outcomes in the intensive care unit

Joshua Malo; Cameron Hypes; Bhupinder Natt; Elaine Cristan; Jeremy Greenberg; Katelin Morrissette; Linda Snyder; James Knepler; John C. Sakles; Kenneth S. Knox; Jarrod Mosier

Background: Intubation in critically ill patients remains a highly morbid procedure, and the optimal approach is unclear. We sought to improve the safety of intubation by implementing a simulation curriculum and monitoring performance with an airway registry. Methods and Methods: This is a prospective, single-center observational study of all intubations performed by the medical intensive care unit (ICU) team over a five-year period. All fellows take part in a simulation curriculum to improve airway management performance and minimize complications. An airway registry form is completed immediately after each intubation to capture relevant patient, operator, and procedural data. Results: Over a five-year period, the medical ICU team performed 1411 intubations. From Year 1 to Year 5, there were significant increases in first-attempt success (72.6 vs. 88.0%, p<0.001), use of video laryngoscopy (72.3 vs. 93.5%, p<0.001), and use of neuromuscular blocking agents (73.5 vs. 88.4%, p<0.001). There were concurrent decreases in rates of desaturation (25.6 vs. 17.1%, p=0.01) and esophageal intubations (5 vs. 1%, p=0.009). Low rates of hypotension (8.3%) and cardiac arrest (0.6%) were also observed. Conclusions: The safety of intubation in critically ill patients can be markedly improved through joint implementation of an airway registry and simulation curriculum.


Journal of bronchology & interventional pulmonology | 2017

The Use of Extracorporeal Membrane Oxygenation in the Bronchoscopic Management of Critical Upper Airway Obstruction.

Bhupinder Natt; James Knepler; Toshinobu Kazui; Jarrod Mosier


Southwest Journal of Pulmonary and Critical Care | 2018

Medical image of the week: post pneumonectomy syndrome

Billie Bixby; James Knepler


Southwest Journal of Pulmonary and Critical Care | 2018

Medical image of the week: mediastinal lipomasosis

Bryan Borg; James Knepler


Journal of bronchology & interventional pulmonology | 2018

Endobronchial Valves Therapy for Advanced Emphysema: A Meta-Analysis of Randomized Trials

See Wei Low; Justin Z. Lee; Hem Desai; Chiu Hsieh Hsu; Afshin R. Sam; James Knepler


Southwest Journal of Pulmonary and Critical Care | 2017

Medical image of the week: saber sheath trachea

See-Wei Low; Huthayfa Ateeli; James Knepler


Southwest Journal of Pulmonary and Critical Care | 2016

Medical image of the week: endobronchial valves

Bhupinder Natt; James Knepler


Southwest Journal of Pulmonary and Critical Care | 2016

Medical image of the week: lung entrapment

Bhupinder Natt; James Knepler

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