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Dive into the research topics where James Nairne is active.

Publication


Featured researches published by James Nairne.


Progress in Medicinal Chemistry | 2015

Imaging in drug development.

James Nairne; Peter Iveson; Andreas Meijer

Imaging has played an important part in the diagnosis of disease and development of the understanding of the underlying disease mechanisms and is now poised to make an impact in the development of new pharmaceuticals. This chapter discusses the underlying technologies that make the field ready for this challenge. In particular, the potentials of magnetic resonance imaging and functional magnetic resonance imaging are outlined, including the new methods developed to provide additional information from the scans carried out. The field of nuclear medicine has seen a rapid increase in interest as advances in radiochemistry have enabled a wide range of new radiotracers to be synthesised.


Journal of Fluorine Chemistry | 2007

Radical scavengers : A practical solution to the reproducibility issue in the fluoridation of diaryliodonium salts

Michael A. Carroll; James Nairne; Graham R. Smith; David A. Widdowson


Journal of Labelled Compounds and Radiopharmaceuticals | 2007

Diaryliodonium salts: a solution to 3‐[18F]fluoropyridine

Michael A. Carroll; James Nairne; John L. Woodcraft


Archive | 2008

IMIDAZOL (1,2-A)PYRIDINES AND RELATED COMPOUNDS WITH ACTIVITY AT CANNABINOID CB2 RECEPTORS

Roger Olsson; Ethan Burstein; Anne Eeg Knapp; Jorgen Eskildsen; Joel Castillo; James Nairne; Veronique Morisson Iveson; Edward Robins; Alex Gibson


Tetrahedron Letters | 2011

The synthesis and evaluation of unsymmetrical dimeric X-ray contrast agents

Duncan Wynn; Gareth Humphries; Veronique Morisson-Iveson; James Nairne; Ian Martin Newington; Joanna Passmore; Lars-Göran Wistrand


Archive | 2012

Heterocyclic compounds as imaging probes of tau pathology

Clare Jones; Amanda Ewan; Duncan Wynn; Alessandra Gaeta; James Nairne


Archive | 2012

RADIOIODINATED TROPANE DERIVATIVES

Michelle Avory; Harry John Wadsworth; James Nairne


Tetrahedron Letters | 2011

The synthesis and evaluation of trimeric X-ray contrast agents

Ian Martin Newington; Gareth Humphries; Nicolas Lasbistes; Veronique Morisson-Iveson; James Nairne; Joanna Passmore; Mikkel Thanning; Lars-Göran Wistrand; Duncan Wynn


Archive | 2011

Use of cyanine dyes for the detection of tau for diagnosis of early-stage tauopathies

Clare Jones; James Nairne


Archive | 2016

An Improved Synthesis of [18F]-fluoroalkyl tosylate

Matthias Glaser; Sajinder K. Luthra; Jane Brown; James Nairne

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