James T. Priestley

Papillomas (so-called) in the non-calculous gallbladder

Abstract Seventy cases of benign intraluminal lesion occurring in noncalculous gallbladders are reported. The type most commonly encountered was the cholesterol polyp, of which there were forty-three cases (62 per cent). The adenomatous polyp was the most rare (three cases, or 4 per cent) and is thought to be the only type capable of becoming malignant. No evidence of transition from the more common types of lesion into true neoplastic adenoma was found. It appears that so-called papillomas of the gallbladder are rarely malignant or premalignant in the absence of gallstones.

The early diagnosis of carcinoma of the large intestine

Abstract The earliest ascertainable clues and symptoms of carcinoma of the colon and rectum have been considered, and factors aiding in an early and positive diagnosis have been reiterated. The most common initial symptoms of malignant growths of the right side of the colon are pain, palpable tumor and indefinite dyspepsia. Lesions in the transverse colon manifest themselves first by pain, obstructive attacks and developing or increasing constipation. Carcinoma of the descending colon and sigmoid is manifested first by increasing constipation or obstruction, pain, rectal bleeding and diarrhea. Carcinoma of the rectosigmoid and rectum is suggested by a change in bowel habit, either constipation or diarrhea, and rectal bleeding. The diagnosis of malignant lesions of the colon is rendered certain by roentgenographic examination. The presence of lesions in the sigmoid or below it may be proved by proctoscopic and digital examination of the rectum.