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Tetrahedron Letters | 2000

Selective deprotection of alkyl t-butyldimethylsilyl ethers in the presence of aryl t-butyldimethylsilyl ethers with bismuth bromide

Joginder S. Bajwa; James Vivelo; Joel Slade; Oljan Repic; Thomas J. Blacklock

Abstract Alkyl t -butyldimethylsilyl ethers can be selectively cleaved in the presence of aryl ethers using a catalytic amount of bismuth bromide in wet acetonitrile at ambient temperatures.


Organic Process Research & Development | 2007

A Concise Synthesis of a Novel Insulin-Like Growth Factor I Receptor (IGF-IR) Inhibitor†

Joel Slade; Joginder S. Bajwa; Hui Liu; David John Parker; James Vivelo; Guang-Pei Chen; John Vincent Calienni; Edwin Bernard Villhauer; Kapa Prasad; Oljan Repic; Thomas J. Blacklock


Organic Process Research & Development | 2006

A practical enantioselective synthesis of a novel peptide deformylase inhibitor

Joel Slade; David John Parker; Michael J. Girgis; Martin Mueller; James Vivelo; Hui Liu; Joginder S. Bajwa; Guang-Pei Chen; Joseph Carosi; Paul Lee; Apurva Chaudhary; Dana Wambser; Kapa Prasad; Kathryn Rene Bracken; Karl Dean; Helmut Boehnke; Oljan Repic; Thomas J. Blacklock


Organic Process Research & Development | 2010

Process Research and Development of a MTP Inhibitor: Another Case of Disappearing Polymorphs upon Scale-up

Mahavir Prashad; Paul Allen Sutton; Raeann Wu; Bin Hu; James Vivelo; Joseph Carosi; Prasad Koteswara Kapa; Jessica Liang


Organic Process Research & Development | 2008

Syntheses of a Triad of Flt3 Kinase Inhibitors : From Bench to Pilot Plant

Wen-Chung Shieh; Joe McKenna; Joseph A. Sclafani; Song Xue; Michael J. Girgis; James Vivelo; Branko Radetich; Kapa Prasad


Organic Process Research & Development | 2005

A Practical Synthesis of the Dual Matrix Metalloprotease/Tumor Necrosis Factor Inhibitor MMP090

Joel Slade; James Vivelo; David John Parker; Joginder S. Bajwa; Hui Liu; Michael J. Girgis; David T. Parker; and Oljan Repič; Thomas J. Blacklock


Archive | 2004

Process for preparing intermediates useful to prepare certain antibacterial n-formyl hydroxylamines

Joel Slade; James Vivelo; Guang-Pei Chen; Joginder S. Bajwa; David John Parker


Organic Process Research & Development | 2002

An Expedient Synthesis of 6α-Fluoroursodeoxycholic Acid

Kurt Königsberger; Guang-Pei Chen; James Vivelo; George E. Lee; John Fitt; Joseph McKenna; Todd M. Jenson; and Kapa Prasad; Oljan Repic


Archive | 2012

SALTS OF AZA-BICYCLIC DI-ARYL ETHERS AND METHODS TO MAKE THEM OR THEIR PRECURSORS

Wolfgang Marterer; Mahavir Prashad; Edwin Bernard Villhauer; Liladhar Murlidhar Waykole; James Vivelo; Bertrand Sutter; Jean-Claude Bianchi; Raeann Wu; Denis Har; Piotr H. Karpinski; Massimo Pignone; Doris Stingelin; Eckart Buerger


Organic Process Research & Development | 2002

An Expedient Synthesis of 6a-Fluoroursodeoxycholic Acid

Kurt Königsberger; Guang-Pei Chen; James Vivelo; George T. Lee; John Fitt; Joseph McKenna; Todd M. Jenson; Kapa Prasad; Oljan Repic

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