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Dive into the research topics where James W. Little is active.

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Featured researches published by James W. Little.


Oral Surgery, Oral Medicine, Oral Pathology | 1976

A clinical study of cysts arising from mucosa of the maxillary sinus

K.A.Thomas Gothberg; James W. Little; Don R. King; Laurence R. Bean

Panorex radiographs taken during the past 5 years at the University of Kentucky College of Dentistry were reviewed for evidence of mucosal cysts of the maxillary sinus. Thirteen patients with this lesion were recalled for re-evaluation of their status. Ten of the patients had symptoms that could be related to the involved sinus. These included stuffiness, fullness, postnasal drip, gushing of yellow fluid from the nose, and headache. Radiographic examination revealed that three of the cysts had increased is size, three had decreased in size, three had not changed in size, and two had disappeared; no evaluation could be made on two. On the basis of radiographic, transillumination, history, and clinical findings, the nine cysts that could be evaluated were diagnosed as being of the nonsecretory type of mucosal cyst. We recommended periodic radiographic examination for this type of lesion. Surgical intervention is necessary only if destruction of surrounding bone has occurred or recurrence of disturbing symptoms is reported.


Journal of Dental Research | 1969

Some Effects of Molybdenum on Connective Tissue

R.H. Johnson; James W. Little; Harmon C. Bickley

Rats fed large quantities of molybdenum for several weeks suffered connective tissue disturbances as revealed by reduced breaking strength of femurs, rupture strength of skin samples, and other tests.


Oral Surgery, Oral Medicine, Oral Pathology | 1980

Dental management of patients with surgically corrected cardiac and vascular disease.

James W. Little

This article deals with the dental management of patients with surgically corrected cardiac and vascular disease. The emphasis of the report is on the susceptibility of these patients to bacterial endocarditis or endarteritis and the prevention of these diseases in the susceptible patient receiving dental treatment. The author would strongly encourage the medical and dental professions to work together in the management of these patients. The dentist must seek medical consultation prior to rendering dental care, and the physician is encouraged to seek dental consultation and treatment for the patient who is going to receive a prosthetic heart valve or is a candidate for heart transplantation.


Journal of Dental Research | 1977

Effects of Parathyroid Extract on the Rupture Strength of Intact Skin of the Rat

James W. Little; James C. Wilson; Haromon C. Bickley; Christie Bickley

Rats were injected with parathyroid extract (PTE) to search for possible effects on connective tissue of the skin. Rupture strength analysis of skin samples showed a significant increase in strength of skin from PTE-treated rats. The explanation for this effect is not understood at present.


Journal of Dental Research | 1966

Effects of Short -Term Lathyrogen Treatment on the Rupture Strength of Healing Wounds

Harmon C. Bickley; James W. Little; Thomas J. Blevins

SYNOPSIS IN INTERLINGUA LE EFFECTOS DE BREVE PERIODOS DE TRACTAMENTO CON LATHYROGENO SUPER LE FORTIA DE RESISTENTIA CONTRA RUPTURAS IN VULNERES DURANTE LE PROCESSO GUARITORI.—Le alterationes de tissu conjunctive incontrate in lathyrismo experimental es possibilemente mediate per le liberation de collagenase tissular. Iste hypothese esseva testate indirectemente per un analyse del fortia tensile de vulneres cutanee in stato guaritori in rattos subjicite a injectiones de fumarato de di-beta-aminopropionitril. Tres consecutive injectiones diurne causava un declino in le fortia de resistentia contra rupturation usque ad un nivello infra illo attingite per vulneres de controlo 3 dies previemente. II pare justificate concluder que iste resultatos se trova in harmonia con le hypothese sub investigation, sed il non es justificate concluder que illos provide un prova de illos in ulle senso del termino. Un studio simultanee del acceptation de sulfato ha remanite inconclusive.


Journal of Dental Research | 1966

Effect of Parathyroid Extract on the Development of Wound Rupture Strength

James W. Little; Harmon C. Bickley; George Hines

SYNOPSIS IN INTERLINGUA EFFECTO DE EXTRACTO PARATHYROIDIC SUPER LE DISVELOPPAMENTO DEL FORTIA RUPTURAL IN VULNERES. -Recente studios ha demonstrate que extracto parathyroidic es capace a stimular un factor collagenolytic in osso. Tamen, le responsa de altere tissus conjunctive a extracto parathyroidic ha non essite determinate con respecto a un tal factor. Le presente studio esseva un essayo de demonstrar le effecto de extracto parathyroidic super primari vulneres de pelle in stato de guarition in juvene rattos. Vulnerate animales recipeva un injection de 200 unitates de extracto parathyroidic omne die durante tres dies ante lor sacrificio. Le animales esseva sacrificate 6, 9, e 12 dies post le vulneration. Un analyse statistic del fortia ruptural del vulneres revelava un significative augmento del fortias in vulneres post 9 dies. Le constatationes esseva interpretate como non supportante le hypothese que extracto parathyroidic stimula un factor collagenolytic in le tissu conjunctive de un vulnere in guarition.


Journal of Dental Research | 1972

Effect of Aquaphor Ointment on Wound Healing

James W. Little; Harmon C. Bickley; William B. Daugherty; Christie Bickley

The effect of Aquaphor and petrolatum ointments on the healing of open granulating wounds in rats was studied. Wounds were observed up to ten days after wounding. The rate of wound contraction and epithelization was measured. Aquaphor- and petrolatum-treated wounds were significantly smaller by day ten. The rate of epithelization was retarded in treated wounds observed six days after wounding, but returned to normal by day ten.


Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology | 2002

Antithrombotic agents: Implications in dentistry

James W. Little; Craig S. Miller; Robert G. Henry; Bruce A. McIntosh


Archive | 2013

Rheumatologic and Connective Tissue Disorders

James W. Little; Donald A. Falace; Craig S. Miller; Nelson L. Rhodus


Archive | 2013

Cancer and Oral Care of the Cancer Patient

James W. Little; Donald A. Falace; Craig S. Miller; Nelson L. Rhodus

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Don R. King

University of Kentucky

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