Jan L. Sechler | Researchain

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Featured researches published by Jan L. Sechler.

Archive | 2006

Triazolopyridazines as tyrosine kinase modulators

Tianbao Lu; Richard S. Alexander; Richard W. Connors; Maxwell D. Cummings; Robert A. Galemmo; Heather Rae Hufnagel; Dana L. Johnson; Ehab Khalil; Kristi Leonard; Thomas P. Markotan; Anna C. Maroney; Jan L. Sechler; Jeremy M. Travins; Robert W. Tuman

Journal of Medicinal Chemistry | 2005

Synthesis and discovery of pyrazine-pyridine biheteroaryl as a novel series of potent vascular endothelial growth factor receptor-2 inhibitors.

Gee-Hong Kuo; Aihua Wang; Stuart Emanuel; Alan Deangelis; Rui Zhang; Peter J. Connolly; William V. Murray; Robert H. Gruninger; Jan L. Sechler; Angel R. Fuentes-Pesquera; Dana L. Johnson; Steven A. Middleton; Linda K. Jolliffe; Xin Chen

Journal of Medicinal Chemistry | 2005

(6,7-Dimethoxy-2,4-dihydroindeno[1,2-c]pyrazol-3-yl)phenylamines: Platelet-Derived Growth Factor Receptor Tyrosine Kinase Inhibitors with Broad Antiproliferative Activity against Tumor Cells

Chih Y. Ho; Donald William Ludovici; Umar Maharoof; Jay Mei; Jan L. Sechler; Robert W. Tuman; Eric Strobel; Laura Andraka; Hwa-Kwo Yen; Gregory C. Leo; Jian Li; Harold R. Almond; Hong Lu; Ann Devine; Rose Tominovich; Judith Baker; Stuart Emanuel; Robert H. Gruninger; Steven A. Middleton; Dana L. Johnson; Robert A. Galemmo

Journal of Medicinal Chemistry | 2005

Synthesis and structure-activity relationships of pyrazine-pyridine biheteroaryls as novel, potent, and selective vascular endothelial growth factor receptor-2 inhibitors.

Gee-Hong Kuo; Catherine Prouty; Aihua Wang; Stuart Emanuel; Alan Deangelis; Yan Zhang; Fengbin Song; Lawrence Beall; Peter J. Connolly; Prahba Karnachi; Xin Chen; Robert H. Gruninger; Jan L. Sechler; Angel R. Fuentes-Pesquera; Steven A. Middleton; Linda K. Jolliffe; William V. Murray

Archive | 2003

N-substituted tricyclic 3-aminopyrazoles as pdfg receptor inhibitors

Chih Yung Ho; Bengt Anders Brunmark; Stuart Emanuel; Jr. Robert A. Galemmo; Dana L. Johnson; Donald William Ludovici; Umar Maharoof; Jay M. Mei; Jan L. Sechler; Eric Strobel; Robert W. Tuman; Hwa Kwo Yen

Archive | 2008

Triazolopiridazinas como moduladores de tirosina cinasas

Archive | 2007

TRIAZOLOPIRIDAZINAS COMO MODULADORES DE QUINASA

Tiambao Lu; Richard S. Alexander; Richard W. Connors; Maxwell D. Cummings; Robert A. Galemmo; Heather Rae Hufnagel; Dana L. Johnson; Ehab Khalil; Kristi Leonard; Thomas P. Markotan; Anna C. Maroney; Jan L. Sechler; Jeremy M. Travins; Robert W. Tuman

Archive | 2006

Protein Kinases in Drug Discovery: Rationale, Success, and Challenge

Jan L. Sechler; Dana L. Johnson

Archive | 2006

Triazolopyridazines as tyrosine kinase

Tianbao Lu; Richard S. Alexander; Richard W. Connors; Maxwell D. Cummings; Robert A. Galemmo; Dana L. Johnson; Ehab Khalil; Kristi Leonard; Thomas P. Markotan; Anna C. Maroney; Robert W. Tuman; Heather Rae Hufnagel; Jeremy M. Travins; Jan L. Sechler

Archive | 2006