Jan Tack

Tegaserod is effective in relieving the multiple symptoms of constipation: results from a 12-week multinational study in patients with chronic constipation

Tegaserod is effective in relieving the multiple symptoms of constipation: results from a 12-week multinational study in patients with chronic constipation

Infective Esophagitis: Inhaled Steroids Treatment for Eosinophilic Esophagitis not Always Safe

A 23-year-old male presented with acute dysphagia and odynophagia for solids. He had multiple episodes of vomiting, retrosternal chest pain and fever but denied shortness of breath of cough. He was previously diagnosed with EoE aged 16 years following presentation with an acute food bolus obstruction, on a background of long standing dysphagia. His other medical history was unremarkable, with no history of allergies or atopy. He had no known history of HSV infection. Following the initial diagnosis, he was treated with inhaled Fluticasone 250mcg 2 puffs twice a day swallowed and Omeprazole 20mg daily with symptomatic relief. The repeat esophagogastroscopy (EGD) showed some persistent ridging and edema. Biopsy showed showed persistent features of EoE with raised eosinophil counts. Overall, he had symptomatic improvement but EoE remained resistant to standard treatment endoscopically and histologically.