Jane E. Sullivan

Sensory dysfunction following stroke: incidence, significance, examination, and intervention.

Abstract Recent studies have provided evidence of the widespread incidence of sensory dysfunction following stroke. The importance of these findings lies in the association between sensory loss poststroke and poorer outcomes in motor capacity, functional abilities, length of inpatient stay, and quality of life. Since literature suggests that clinicians can use information about clients’ sensory status to predict rehabilitation outcomes and select appropriate interventions, the accuracy of somatosensory assessment is extremely clinically relevant. However, many of the clinical tests that are commonly used to examine sensation have not been found to be valid or reliable. Emerging evidence supports the efficacy of several interventions that target the sensory systems. This article reviews the incidence, significance, examination, and interventions for sensory dysfunction following stroke and summarizes the important characteristics of interventions directed at somatosensation.

Outcome Measures for Individuals With Stroke: Process and Recommendations From the American Physical Therapy Association Neurology Section Task Force

Background and Purpose The use of standardized outcome measures (OMs) can support clinicians development of appropriate care plans, guide educators in curricular decisions, and enhance the methodological quality and generalizability of clinical trials. The purposes of this case report are: (1) to describe a framework and process for assessing psychometrics and clinical utility of OMs used poststroke; (2) to describe a consensus process used to develop recommendations for stroke-related OMs in clinical practice, research, and professional (entry-level) physical therapist education; (3) to present examples demonstrating how the recommendations have been utilized to date; and (4) to make suggestions for future efforts. Case Description A task force of 7 physical therapists with diverse clinical and research expertise in stroke rehabilitation used a 3-stage, modified Delphi consensus process to develop recommendations on OM use. An evidence-based systematic review template and a 4-point rating scheme were used to make recommendations on OM use by care setting and patient acuity, for research, and for inclusion in professional education. Outcomes An initial list of 77 OMs was developed based on input from numerous professional sources. Screening measures and duplicate measures were eliminated. Fifty-six OMs received full review. Measures spanned the constructs of body structure/function (21), activity (28), and participation (14). Fourteen measures received a rating of “highly recommend.” Discussion Use of highly recommended OMs may provide a common set of tools enabling comparisons across patients, interventions, settings, and studies. The use of a clearly defined, comprehensive assessment template may facilitate the pooling of data on OMs and contribute to best practice guidelines. Educational recommendations may inform curricular decisions.

Outcome measures in neurological physical therapy practice: part I. Making sound decisions.

Standardized outcome measures (OMs) are a vital part of evidence-based practice. Despite the recognition of the importance of OMs, recent evidence suggests that the use of OMs in clinical practice is limited. Selecting the most appropriate OM enhances clinical practice by (1) identifying and quantifying body function and structure limitations; (2) formulating the evaluation, diagnosis, and prognosis; (3) informing the plan of care; and (4) helping to evaluate the success of physical therapy interventions. This article (Part I) is the first of a 2-part series on the process of selecting OMs in neurological clinical practice. We introduce a decision-making framework to guide the selection of OMs and discuss 6 main factors—what to measure, the purpose of the measure, the type of measure, patient and clinic factors, psychometric factors, and feasibility—that should be considered when selecting OMs for clinical use. The framework will then be applied to a patient case in Part II of the series (see the article “Outcome Measures in Neurological Physical Therapy Practice: Part II. A Patient-Centered Process” in this issue).

Effects of home-based sensory and motor amplitude electrical stimulation on arm dysfunction in chronic stroke

Objective: To examine the effects of a home-based arm exercise programme of sensory and motor amplitude electrical stimulation. Design: Non-concurrent, multiple-baseline, single-subject design. Subjects: Ten adults with chronic arm hemiparesis following stroke. Subjects ranged in age from 38 to 74 years and were 2-16 years post stroke. Three subjects had right-sided involvement; seven had left. Intervention: Subjects completed an eight-week, individualized, home programme of neuromuscular and sensory amplitude electrical stimulation. All subjects engaged in stimulation-assisted task-specific exercises for 15 minutes 2 -3 times daily. Participants with sensory deficits received an additional 15 minutes of sensory amplitude stimulation twice daily. The Action Research Arm Test was used to examine arm function; the Stroke Rehabilitation Assessment of Movement was used to examine movement quality; and the Modified Ashworth Assessment of Spasticity was used to examine muscle tone. Results: A statistically significant improvement was demonstrated by six of the 10 subjects on the Action Research Arm Test, and five subjects on the Stroke Rehabilitation Assessment of Movement. Four subjects had ≥ 10% improvement on the Modified Ashworth Assessment of Spasticity. Two subjects demonstrated significant improvement on all three outcome measures; six subjects improved on two or more measures; and seven subjects improved on one or more measure. Subjects who improved on two or more measures tended to have had more recent onset of stroke, were older and had higher baseline motor and functional capacity. Conclusion: Subjects with chronic stroke can experience impairment and functional improvements following a home-based programme of motor and sensory amplitude electrical stimulation.

Outcome measures in neurological physical therapy practice: part II. A patient-centered process.

Physical therapists working in neurological practice must make choices about which standardized outcome measures are most appropriate for each patient. Significant time constraints in the clinic limit the number of measures that one can reasonably administer. Therapists must choose measures that will provide results that guide the selection of appropriate interventions and are likely to show clinically meaningful change. Therefore, therapists must be able to compare the merits of available measures to identify those that are most relevant for each patient and setting. This article describes a process for selecting outcome measures and illustrates the use of that process with a patient who has had a stroke. The link between selecting objective outcome measures and tracking patient progress is emphasized. Comparisons are made between 2 motor function measures (the Fugl-Meyer Assessment [FMA] of Physical Performance vs the Stroke Rehabilitation Assessment of Movement), and 2 balance measures (Berg Balance Scale vs the Activities-specific Balance Confidence Scale). The use of objective outcome measures allows therapists to quantify information that previously had been described in subjective terms. This allows the tracking of progress, and the comparison of effectiveness and costs across interventions, settings, providers, and patient characteristics.

Neuromuscular electrical stimulation during task-oriented exercise improves arm function for an individual with proximal arm dysfunction after stroke.

Hedman LD, Sullivan JE, Hilliard MJ, Brown DM: Neuromuscular electrical stimulation during task-oriented exercise improves proximal arm dysfunction after stroke. Am J Phys Med Rehabil 2007;86:592–596. This case report examined the effectiveness of a home program using neuromuscular electrical stimulation (NMES) during voluntary task-oriented exercise to achieve functional and impairment improvements for an individual with primarily proximal arm paresis after a stroke. The subject initially achieved a Fugl–Meyer Assessment (FMA) score of 58/66, but she reported minimal functional use of her involved, dominant arm. The 6-wk intervention consisted of NMES-assisted task practice involving repetitive reaching for and manipulation of small objects for three daily 15-min sessions. The subject applied NMES to the deltoid and triceps brachii muscles to augment shoulder flexion and abduction and elbow extension during task practice. Outcome measures included the FMA, the Action Research Arm Test (ARAT), and the Motor Activity Log Quality of Movement subscale (MAL-QOM). The FMA remained unchanged, but the ARAT and MAL-QOM showed improvements, from the beginning to the conclusion of the intervention, that were maintained at 6-wk follow-up.

Feasibility and outcomes of a community-based, pedometer-monitored walking program in chronic stroke: A pilot study

Abstract Background and Purpose: After stroke, many individuals have reduced physical activity. Pedometer use is reported to enhance physical activity in patients with other health conditions. The purpose of this study was to investigate the feasibility of a community-based, pedometer-monitored walking program and determine its effects on gait speed and distance, quality of life, and balance self-efficacy post stroke. Methods: A single-group, pretest-posttest follow-up design was used. Eleven individuals with chronic stroke (mean age, 60.4 years; mean time since stroke, 12.2 years) completed a pedometer-monitored, community-based intervention. Primary outcomes were the 6-minute walk test (6MWT) and 10-meter walk test. Secondary outcomes were the Activities-Specific Balance Confidence Scale, Stroke Impact Scale-16 (SIS-16), and a pedometer satisfaction survey. Subjects used pedometers daily for 6 weeks and recorded step counts, adverse symptoms, and exertion levels in exercise diaries. Weekly phone coaching was used to set walking goals. Results: No adverse events occurred. All subjects were able to don pedometers, 91% could read step counts, and 80% expressed satisfaction. There were no significant group changes across outcome measures. There were moderate effect sizes for changes in SIS-16 (0.312) and 6MWT (0.293). Increasing steps correlated with increased perception of physical function. Discussion: The results support the feasibility of and participant satisfaction with a community-based, pedometer-monitored walking program post stroke. Limitations include small sample size and lack of a comparison group. Conclusions: This study represents a preliminary step in determining the effectiveness of pedometer-based interventions for enhancing physical activity in persons with chronic stroke. Further study is warranted.

Afferent stimulation provided by glove electrode during task-specific arm exercise following stroke

Background: Sensory amplitude electrical stimulation (SES) and repetitive task practice reduce impairments and arm dysfunction when delivered separately following stroke. Objective: To determine if home-based, task-specific arm exercise was more effective when administered concurrent with SES. Methods: Thirty-eight subjects with chronic stroke and mean Fugl-Meyer Assessment (FMA) score 28/66 (15–45) participated. Subjects were randomly assigned to an SES (n = 20) or sham stimulation (n = 18) group. Subjects engaged in task-based home exercise for 30 minutes, twice daily, for four weeks while wearing a glove electrode on the impaired hand. Experimental subjects received SES while control subjects received sham stimulation during exercise. Primary outcome measures: FMA and Arm Motor Ability Test (AMAT). Results: There were no significant between-group differences for outcome measures. There was a significant difference between the pre- and post-test scores in the SES group AMAT median time (P = 0.003 95% confidence interval (CI): −14.304, −6.365; effect size: 0.84). Practice time was not associated with changes in outcomes. Subjects with more sensorimotor dysfunction had significantly greater improvements on AMAT median time (P = 0.037). There was a significant relationship between baseline FMA score and FMA change score (r = 0.402; P = 0.006). Conclusions: This study describes a unique SES delivery system via glove electrode that enabled delivery of SES during home-based arm task practice in stroke survivors. Task practice with concurrent SES did not demonstrate significantly better effects than task practice with sham stimulation, however there was a trend for greater improvement in one activity measure.

Improving arm function in chronic stroke: a pilot study of sensory amplitude electrical stimulation via glove electrode during task-specific training

Abstract Objective: To investigate the effects of sensory amplitude electrical stimulation (SES) delivered by glove electrode during task-specific exercise on arm movement, function, and sensation in chronic stroke. Methods: The design was an intervention pilot study, pre-test, post-test, follow-up design. The settings used were a university research laboratory and home-based intervention. Participants comprised of 11 individuals with chronic stroke (7.2u2009±u20094.1 years post onset) and moderate arm paresis, 10.82/20u2009±u20092.27 on the Stroke Rehabilitation Assessment of Movement (STREAM) — Arm Subscale. Participants were seven males and four females (mean age: 59 years). Participants were recruited from university-based database. Intervention- Participants engaged in task-specific training at home for 30 min, twice daily, for 5 weeks, while receiving SES via glove electrode. Participants received supervised task practice at least twice during intervention period for 1 hour. Main outcome measures- Jebsen–Taylor Hand Function Test (JTHFT), STREAM — Arm Subscale, Motor Activity Log-14 (MAL-14) — Amount and Quality Subscales, and Nottingham Stereognosis Assessment (NSA). Results: Significant changes were found in group mean pre- and post-test comparisons on the NSA (Pu2009=u20090.042), MAL amount subscale (Pu2009=u20090.047), and JTHFT (with writing item 29 excluded) (Pu2009=u20090.003) and in pre-test to follow-up comparisons on NSA (Pu2009=u20090.027) and JTHFT (writing item excluded) (Pu2009=u20090.009). There was no significant change on the STREAM (Pu2009=u20091.0). Individuals with a greater baseline motor capacity determined by STREAM scores (Pu2009=u20090.048) and more recent stroke (Pu2009=u20090.014) had significantly greater improvements. Conclusion: Combining task-specific training with glove-based SES in chronic stroke resulted in changes in arm sensation and function that were maintained at 3-month follow-up.

An initial exploration of the perceptual threshold test using electrical stimulation to measure arm sensation following stroke

Objective: To explore the viability of the perceptual threshold test using electrical stimulation to measure light touch sensation in the hands of stroke survivors. Design: Descriptive study. Setting: University research laboratory. Subjects: Twenty-nine adult community-dwelling chronic stroke survivors. Main measure(s): Perceptual threshold test using electrical stimulation, stroke rehabilitation assessment of movement, Nottingham sensory assessment for stereognosis, action research arm test, Fugl-Meyer assessment of sensation and motor activity log 14. Results: Perceptual threshold test using electrical stimulation mean threshold values were 1.23 (0.6) milliamperes (range 0.5–3.5) for the uninvolved side and 1.68 (0.91) milliamperes (range 0.5–4.5) for the involved side. The perceptual threshold test using electrical stimulation demonstrated excellent intra-rater reliability (intraclass correlation coefficientu2009=u20090.896 – uninvolved; 0.829 – involved). There was a statistically significant difference between the perceptual threshold test using electrical stimulation mean threshold values for the uninvolved and involved arms (Pu2009=u20090.003), but this significance did not hold for subjects who had normal sensation as measured by the Fugl-Meyer assessment of sensation (Pu2009=u20090.083). Low to nonexistent correlations were found between the perceptual threshold test using electrical stimulation and other measures of sensation, arm movement, activity and participation. Conclusions: The perceptual threshold test using electrical stimulation is a reliable and clinically feasible test with the potential to identify sensory capacity in stroke survivors with substantial sensory loss. Electrical sensory thresholds do not reflect overall sensory function or motor capabilities in stroke survivors.