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Janet M. Cameron

University of Hertfordshire

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Publication

Featured researches published by Janet M. Cameron.

Journal of The Chemical Society, Chemical Communications | 1988

Synthesis and enzymatic resolution of carbocyclic 2′-ara-fluoro-guanosine: a potent new anti-herpetic agent

Alan D. Borthwick; Suzanne Butt; Keith Biggadike; Anne M. Exall; Stanley M. Roberts; Peter Youds; Barrie E. Kirk; Brian R. Booth; Janet M. Cameron; Susan W. Cox; Clara L.P. Marr; Mark D. Shill

(±)-Carbocyclic-9-(2′-deoxy-2′-β-fluoroarabinofuranosyl) guanine (8) and the corresponding furanose compound (12) have been synthesised; the former compound [which was resolved by formation of the monophosphate (20) and enantioselective hydrolysis using a 5′-nucleotidase] is an extremely potent inhibitor of herpes simplex viruses types 1 and 2.

Bioorganic & Medicinal Chemistry Letters | 1993

A novel class of 1,3-oxathiolane nucleoside analogues having potent anti-HIV activity

Bernard Belleau; Livio Brasili; Laval Chan; Marika P. DiMarco; Boulos Zacharie; Nghe Nguyen-Ba; Helen J. Jenkinson; Jonathan Coates; Janet M. Cameron

Abstract We have developed a novel class of 1,3-oxathiolane nucleoside analogues which were evaluated for anti-HIV activity in the MT-4 cell line. BCH-371 , the adenine derivative, has been found to exhibit significant anti-HIV activity.

Nature | 1993

Rational design of potent sialidase-based inhibitors of influenza virus replication

Mark von Itzstein; Wen-Yang Wu; Gaik B. Kok; Michael S. Pegg; Jeffrey Clifford Dyason; Betty Jin; Tho Van Phan; Mark L. Smythe; Hume Forrest White; Stuart W. Oliver; Peter M. Colman; Joseph N. Varghese; D. Michael Ryan; Jacqueline M. Woods; Richard C. Bethell; Vanessa J. Hotham; Janet M. Cameron; Charles R. Penn

Biochemical Pharmacology | 1992

Cellular metabolism of (−) enantiomeric 2′-deoxy-3′-thiacytidine

Nicholas Cammack; Philippa Rouse; Clara L.P. Marr; Paula J. Reid; Richard Boehme; Jonathan Coates; Charles R. Penn; Janet M. Cameron

Biochemical Pharmacology | 1995

The intracellular phosphorylation of (−)-2′-deoxy-3′-thiacytidine (3TC) and the incorporation of 3TC 5′-monophosphate into DNA by HIV-1 reverse transcriptase and human DNA polymerase γ

Norman M. Gray; Clara L.P. Marr; Charles R. Penn; Janet M. Cameron; Richard C. Bethell

Antiviral Research | 1991

CARBOVIR : THE (-) ENANTIOMER IS A POTENT AND SELECTIVE ANTIVIRAL AGENT AGAINST HUMAN IMMUNODEFICIENCY VIRUS IN VITRO

Jonathan Allan Coates; Helen J. Inggall; Bridget A. Pearson; Charles R. Penn; Richard Storer; Christopher Williamson; Janet M. Cameron

Archive | 1992

Antiviral combinations containing nucleoside analogs

Janet M. Cameron; Nicholas Cammack

Archive | 1992

Nukleosidanalogen enthaltende Antiviren-Zubereitungen. Nucleoside analogues containing anti-virus preparations.

Janet M. Cameron; Nicholas Cammack

Archive | 1992

Combinaisons antivirales contenant des analogues de nucleosides

Janet M. Cameron; Nicholas Cammack

Archive | 1992

Thiacytidine (3TC)5'-Triphosphate on HumanImmunodeficiency VirusReverseTranscriptase and MammalianDNA Polymerases Alpha,Beta,andGamma

Norman M. Gray; Janet M. Cameron

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Charles R. Penn

University of Hertfordshire

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Clara L.P. Marr

University of Hertfordshire

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Jonathan Coates

University of Wollongong

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Norman M. Gray

University of Hertfordshire

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Richard C. Bethell

Boehringer Ingelheim

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Jeffrey Clifford Dyason

Griffith University

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Joseph N. Varghese

Commonwealth Scientific and Industrial Research Organisation

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Mark L. Smythe

University of Queensland

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Mark von Itzstein

Griffith University

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Peter M. Colman

University of Melbourne

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