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Dive into the research topics where Jannie Lea Baker is active.

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Featured researches published by Jannie Lea Baker.


Tetrahedron Letters | 2001

An efficient method to prepare α-sulfonyl hydroxamic acid derivatives

Vincent Sandanayaka; Arie Zask; A.M. Venkatesan; Jannie Lea Baker

Abstract α-Sulfonyl hydroxamic acid derivatives are biologically important molecules. An efficient protocol has been developed to make these molecules via a direct sulfonylation of enolates. Several piperidine containing α-sulfonyl hydroxamic acid compounds have been prepared by this procedure.


Archive | 1998

N-hydroxy-2-(alkyl, aryl, or heteroaryl sulfanyl, sulfinyl, or sulfonyl)-3-substituted alkyl, aryl or heteroarylamides as matrix metalloproteinase inhibitors

A.M. Venkatesan; George Theodore Grosu; Jamie Marie Davis; Baihua Hu; Derek Cecil Cole; Jannie Lea Baker; Marcy Pamela Jacobson; Matthew Robin O'Dell


Journal of Medicinal Chemistry | 2003

Synthesis and structure-activity relationship of N-substituted 4-arylsulfonylpiperidine-4-hydroxamic acids as novel, orally active matrix metalloproteinase inhibitors for the treatment of osteoarthritis

Venkatesan Aranapakam; Jamie Marie Davis; George Theodore Grosu; Jannie Lea Baker; John W. Ellingboe; Arie Zask; Jeremy I. Levin; Vincent Sandanayaka; Mila Du; Jerauld S. Skotnicki; John F. DiJoseph; Amy Sung; Michele A. Sharr; Loran M. Killar; Thomas Walter; Guixian Jin; Jeff Tillett; Weiguang Zhao; and Joseph McDevitt; Zhang Bao Xu


Journal of Medicinal Chemistry | 2003

Synthesis and Structure−Activity Relationship of α-Sulfonylhydroxamic Acids as Novel, Orally Active Matrix Metalloproteinase Inhibitors for the Treatment of Osteoarthritis

Venkatesan Aranapakam; George Theodore Grosu; Jamie Marie Davis; Baihua Hu; John W. Ellingboe; Jannie Lea Baker; Jerauld S. Skotnicki; Arie Zask; John F. DiJoseph; Amy Sung; Michele A. Sharr; Loran M. Killar; Thomas Walter; Guixian Jin


Journal of Medicinal Chemistry | 2004

Synthesis and Structure−Activity Relationships of 4-alkynyloxy Phenyl Sulfanyl, Sulfinyl, and Sulfonyl Alkyl Hydroxamates as Tumor Necrosis Factor-α Converting Enzyme and Matrix Metalloproteinase Inhibitors

Aranapakam Mudumbai Venkatesan; Jamie Marie Davis; George Theodore Grosu; Jannie Lea Baker; Arie Zask; Jeremy I. Levin; John W. Ellingboe; Jerauld S. Skotnicki; John F. DiJoseph; Amy Sung; Guixian Jin; Weixin Xu; Diane Joseph Mccarthy; Dauphine Barone


Archive | 2001

Method for preparing alpha-sulfonyl hydroxamic acid derivatives

Vincent Sandanayaka; Arie Zask; Aranapakam Mudumbai Venkatesan; Jannie Lea Baker; Lalitha Krishnan; Sreenivasulu Megati; Joseph Zeldis


Archive | 1998

N-hdroxy-2-(alkyl, aryl, or heteroaryl, sulfanyl, sulfinyl or sulfonyl)-3-substituted alkyl, aryl or heteroarylamides as matrix metalloproteinase inhibitors

A.M. Venkatesan; George Theodore Grosu; Jamie Marie Davis; Jannie Lea Baker; Jeremy I. Levin


Archive | 2001

Alkynyl containing hydroxamic acid compounds as matrix metalloproteinase/tace inhibitors

Jeremy I. Levin; A.M. Venkatesan; J.M. Chen; Arie Zask; Vincent Premaratna Sandanayaka; Mila T. Du; Jannie Lea Baker


Archive | 2000

Alkynyl containing hydroxamic acid derivatives, their preparation and their use as matrix metalloproteinase (mmp) inhibitors / tnf-alpha converting enzyme (tace) inhibitors

Jeremy I. Levin; Aranapakam Mudumbai Venkatesan; James M. Chen; Arie Zask; Vincent Sandanayaka; Mila Ti Du; Jannie Lea Baker


Tetrahedron Letters | 2001

An efficient method to prepare a-sulfonyl hydroxamic acid derivatives

Vincent Sandanayaka; Arie Zask; A.M. Venkatesan; Jannie Lea Baker

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Jeremy I. Levin

Pennsylvania State University

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Amy Sung

Princeton University

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