Janos Porszasz

Changes in skeletal muscle oxygenation during incremental exercise measured with near infrared spectroscopy

AbstractTo determine the change in muscle oxygenation in response to progressively increasing work rate exercise, muscle oxyhemoglobin + oxymyoglobin saturation was measured transcutaneously with near infrared spectroscopy in the vastus lateralis muscle during cycle ergometry. Studies were done in 11 subjects while gas exchange was measured breath-by-breath. As work rate was increased, tissue oxygenation initially either remained constant near resting levels or, more usually, decreased. Near the work rate and metabolic rate where significant lactic acidosis was detected by excess CO2 production (lactic acidosis threshold, LAT), muscle oxygenation decreased more steeply. As maximum oxygen uptake (

Skeletal muscle oxygenation during constant work rate exercise.

\dot V{\text{O}}_{\text{2}}

Gas exchange responses to continuous incremental cycle ergometry exercise in primary pulmonary hypertension in humans.

) was approached, the rate of desaturation slowed. In 8 of the 11 subjects, tissue O2 saturation reached a minimum which was sustained for 1–3 min before

Responses to constant work rate bicycle ergometry exercise in primary pulmonary hypertension: the effect of inhaled nitric oxide

\dot V{\text{O}}_{{\text{2max}}}

Effects of Tiotropium on Hyperinflation and Treadmill Exercise Tolerance in Mild to Moderate Chronic Obstructive Pulmonary Disease

was reached. The LAT correlated with both the