Jasmina Primozic

Early crossbite correction: a three-dimensional evaluation

A crossbite (CB) occurs in approximately 4-23 per cent of young children and may lead to mandibular and facial asymmetry. Therefore, early intervention is often necessary to create conditions for normal occlusal and facial development. The aim of this study was to assess facial asymmetry and palatal volume (pre- and post-treatment) in two groups of children, one with a unilateral CB and the other with no crossbite (NCB). Thirty children with CB (13 males, 17 females, mean age 4.9 +/- 0.98 years) and 28 children with NCB (17 males, 11 females, mean age 5.3 +/- 0.36 years) were included in the study. Those with a CB were treated with an intra-oral expansion appliance. The faces and dental casts of the children were scanned using a three-dimensional (3D) laser scanning device at baseline (T0) and after six months (T1) of treatment. Students t-tests were used to assess differences between the two groups in facial symmetry and palatal volume over the 6 month period. The CB children had statistically significantly greater asymmetry of the face (P = 0.042), especially the lower third (P = 0.039), and a significantly smaller palatal volume (P = 0.045) than the NCB subjects at baseline. There were no statistically significant differences between the two groups at T1. Treatment of a CB in the primary dentition corrected the facial asymmetry, particularly the lower part of the face. The palatal volume of the CB children increased as a result of orthodontic intervention to similar levels exhibited by the NCB children.

Assessment of facial asymmetry in growing subjects with a three-dimensional laser scanning system

OBJECTIVES To evaluate facial asymmetry in growing subjects with no malocclusion on three-dimensional laser facial scans. SETTING AND SAMPLE POPULATION Twenty-seven healthy Caucasian children (15 boys and 12 girls, aged 5.4 ± 0.3 years) in the primary dentition without malocclusion were randomly selected from a local kindergarten in Slovenia. MATERIAL AND METHODS Surface facial images were obtained using a three-dimensional laser scanning system at baseline and at 18, 30, 42 and 54 months of follow-up. Facial asymmetry was assessed quantitatively by measuring the average distance between facial image and mirrored image. Further, the percentage of asymmetry was calculated as the percentage of image to mirrored image not coinciding within 0.5 mm. Qualitative assessment was performed on colour deviation maps by recording the predominant side of the face for the upper, middle and lower parts of the face separately. Nonparametric tests were used for data analysis. RESULTS No face was perfectly symmetric. The average distance between the mirrored images for the whole face ranged 0.22-0.85 mm and the percentage of asymmetry 7.8-66.9. There were no significant gender differences (p > 0.05), and no significant change was found over the observed period. The upper part of the face was the least asymmetric, while the lower and middle parts showed similar degrees of asymmetry. CONCLUSION Facial asymmetry is already present at an early developmental stage and does not show any tendency to increase or decrease with growth in the pre-pubertal period.

The association of tongue posture with the dentoalveolar maxillary and mandibular morphology in Class III malocclusion: a controlled study.

The aim of the present study was to evaluate the association of tongue posture with the dentoalveolar maxillary and mandibular morphology in a group of Class III subjects in comparison to a group of Class I subjects. Twenty Class III subjects (9 males, 11 females, 19.2 ± 4.6 years) and 20 Class I subjects (6 males, 14 females, 17.4 ± 1.7 years) were included in the present study. Maxillary and mandibular morphology was defined by the intermolar and intercanine distances, at both the cusps and gingival levels, and by measuring surface area and volume of the palatal vault and mouth floor assessed on three-dimensional digital models. Tongue-to-palate distances were measured on lateral cephalograms. The groups were compared using the Mann-Whitney U-test and correlations between each morphological parameter and the tongue-to-palate distances were calculated using the Spearman correlation coefficient. The mandibular intermolar width at the gingival level was significantly greater in the Class III group (P < 0.01), while the maxillary intercanine widths were significantly smaller in the Class III group (P < 0.05). The mouth floor area and volume and the respective ratios between the mouth floor and palate were significantly greater in the Class III group (P = 0.01). The tongue-to-palate distances were generally greater, i.e. lower tongue posture, for the Class III subjects. Significant correlations were seen between tongue-to-palate distances in the posterior region with the area ratio (rho = 0.44, P < 0.05). Tongue posture is significantly lower in Class III subjects and is associated with the dentoalveolar characteristics of the maxilla and mandible.

Palatal surface and volume in mouth-breathing subjects evaluated with three-dimensional analysis of digital dental casts - A controlled study

OBJECTIVE To compare the anatomical characteristics of the maxillary arch, identified as palatal surface area and volume, between mouth-breathing and nose-breathing subjects using a three-dimensional (3D) analysis of digital dental casts. METHODS Twenty-one Caucasian subjects (14 females and 7 males) with a mean age of 8.5 years [standard deviation (SD) 1.6 years] were selected according to the following criteria: mouth-breathing pattern due to allergic rhinitis, early mixed dentition, skeletal Class I relationship, and pre-pubertal stage of cervical vertebral maturation. This study group (SG) was compared with a control group (CG) of 17 nose-breathing subjects (9 females and 8 males, mean age: 8.5 years; SD: 1.7 years). For each subject, initial dental casts were taken and the upper arch was scanned using a 3D laser scanner. On each digital model, 3D measurements were performed to analyse maxillary arch morphology. Between-group differences were tested with the independent sample Students t-test (P < 0.05). RESULTS In mouth-breathing subjects, changes in physiological function of the upper respiratory tract resulted in skeletal adaptations of the maxillary arch. In the SG, both palatal surface area and volume were significantly smaller when compared with values of the CG. In particular, the palatal surface area and palatal volume were, respectively, 13.5 and 27.1 per cent smaller in the SG when compared to the CG. CONCLUSIONS Subjects with prolonged mouth breathing showed a significant reduction of the palatal surface area and volume leading to a different development of the palatal morphology when compared with subjects with normal breathing pattern.

Three-dimensional assessment of facial asymmetry among pre-pubertal class III subjects: a controlled study

BACKGROUND/OBJECTIVE Facial asymmetry is very common in adult class III patients; however, the degree of facial asymmetry in growing class III subjects has been poorly investigated. Therefore, the aim was to assess the degree of facial asymmetry of growing class III subjects and to compare it with a sample of growing subjects without malocclusion, recorded using a three-dimensional laser scanning method and classified according to the dentition phase. SUBJECTS/METHODS A group of 156 Caucasian subjects, 52 with class III malocclusion (28 females and 24 males) and 104 without malocclusion (control, 51 females and 53 males), with an overall mean age 6.7±1.4 years (range 4.3-10.3 years), were included. The subjects were further subdivided according to the presence of either primary or early/intermediate mixed dentitions. Facial asymmetry was assessed on three-dimensional surface facial images obtained using a laser scanning device in terms of mirrored face distances and percentages of asymmetry. Multivariate analyses were used to assess the differences among class III and control groups. RESULTS Complete facial symmetry was not seen in any subject. No significant differences of facial asymmetry were observed between the class III and control groups, neither in the primary nor in the early/intermediate mixed dentition phases. LIMITATIONS No conclusions about longitudinal changes in the degree of facial asymmetry among class III subjects could be drawn from the present cross-sectional study. CONCLUSIONS Based on three-dimensional facial asymmetry analysis, class III subjects do not show clinically relevant facial asymmetry, at least during the pre-pubertal growth period.

Gingival crevicular fluid alkaline phosphate activity during the retention phase of maxillary expansion in prepubertal subjects: A split-mouth longitudinal study

INTRODUCTION The aim of this study was to monitor the alveolar bone formation at the tension sites of teeth supporting the appliances for rapid maxillary expansion (RME) during the retention phase according to the local gingival crevicular fluid (GCF) alkaline phosphatase (ALP) activity. METHODS This split-mouth prospective study included 23 prepubertal subjects (15 girls, 8 boys; mean age, 9.0 ± 1.4 years) who had a constricted maxillary arch and were undergoing RME. Periodontal parameters, including probing depth, were recorded at 3 and 6 months after RME. Furthermore, the GCF ALP activity was measured at the tension sites of the supporting test teeth (TT) and at the antagonist control teeth (CT) sites. RESULTS Periodontal parameters were generally similar between the TT and CT sites during the study, with the exception that probing depth underwent a slight increase at the TT sites. At baseline, the GCF ALP activity was similar between the TT and CT sites; however, at both 3 and 6 months, significantly greater enzymatic activity was seen at the TT sites. The overall probing depth changes were not significantly correlated with the corresponding GCF ALP activity changes for either the TT or the CT sites. CONCLUSIONS Alveolar bone formation at the tension sites would last up to 6 months of retention after RME. These results warrant more comprehensive studies to assess whether the GCF ALP activity has potential as a diagnostic tool for bone formation during the retention phase of RME.

Cervical vertebral maturation method and mandibular growth peak: a longitudinal study of diagnostic reliability

Background/objectives The capability of the cervical vertebral maturation (CVM) method in the identification of the mandibular growth peak on an individual basis remains undetermined. The diagnostic reliability of the six-stage CVM method in the identification of the mandibular growth peak was thus investigated. Subjects/Methods From the files of the Oregon and Burlington Growth Studies (data obtained between early 1950s and middle 1970s), 50 subjects (26 females, 24 males) with at least seven annual lateral cephalograms taken from 9 to 16 years were identified. Cervical vertebral maturation was assessed according to the CVM code staging system, and mandibular growth was defined as annual increments in Co-Gn distance. A diagnostic reliability analysis was carried out to establish the capability of the circumpubertal CVM stages 2, 3, and 4 in the identification of the imminent mandibular growth peak. Results Variable durations of each of the CVM stages 2, 3, and 4 were seen. The overall diagnostic accuracy values for the CVM stages 2, 3, and 4 were 0.70, 0.76, and 0.77, respectively. These low values appeared to be due to false positive cases. Limitations Secular trends in conjunction with the use of a discrete staging system. In most of the Burlington Growth Study sample, the lateral head film at age 15 was missing. Conclusions/Implications None of the CVM stages 2, 3, and 4 reached a satisfactorily diagnostic reliability in the identification of imminent mandibular growth peak.

Three-dimensional evaluation of the maxillary arch and palate in unilateral cleft lip and palate subjects using digital dental casts

Objectives To assess arch width, palatal surface area, and volume in surgically treated unilateral cleft lip and palate (UCLP) in mixed dentition children in comparison with non-cleft lip and palate (NCLP) children using a 3D laser scanning. Materials and Methods 38 subjects (Caucasian origin), 5.63-11.9 years of age (mean, 9.33 ± 1.67 years), were included. 19 in each group (UCLP and NCLP). Digital dental casts were obtained using a 3 Shape R700 laser scanner. Intercanine and intermolar widths (cusp and gingival levels), palatal surface area and volume were measured. An independent sample Students t-test and an ANOVA were undertaken with significance level set as P < 0.05. Results Intercanine widths at the cusp (5.60 mm; P < 0.001) and at the gingival level (3.11 mm; P = 0.014), palatal area (141.5 mm2; P = 0.009) and volume (890.7 mm3; P = 0.029) were significantly lower in the UCLP compared to the control group. Limitations A smaller part of the subjects was in late mixed dentition phase. To overcome this limitation a matched control group was used. In seven subjects with UCLP, some teeth were missing, which might have had an influence on the dental measurements. However, these subjects could not be excluded because eliminating more severely affected subjects, would have introduced bias. Conclusions Three-dimensional evaluation of the maxillary arch and palate highlighted significant differences between UCLP and non-UCLP subjects in mixed dentition phase, suggesting that orthopaedic maxillary expansion is advisable in UCLP.

Temporomandibular clinical exploration in Italian adolescents

Abstract Objective: This study investigated the prevalence of the signs and symptoms of temporomandibular disorders (TMD) among Italian adolescents. Methods: The data were recorded from 567 subjects (246 males and 321 females; age range 11–19 years), grouped according to age and molar class relationship. Results: Forty-four point one percent of subjects showed at least one sign or symptom of TMD, which were significantly more frequent in the 16–19 year-old group (52.9%) in respect to the 11–15 year-old group (39.8%) (χ 2 = 8.78; p = 0.003). Signs and/or symptoms were about 1.6 times more frequent in subjects with Class II/1 malocclusion (χ 2 = 13.3, p = 0.0003), mostly for TMJ sounds (χ 2 = 1.444; p = 0.036). Myalgia was more frequent in females than in males (χ 2 = 3.882; p = 0.049). Conclusion: TMD signs and/or symptoms among Italian adolescents seem diffused (44.1%). Therefore, all adolescents should be screened thorough medical history and clinical examination.

Diagnostic reliability of mandibular second molar maturation in the identification of the mandibular growth peak: A longitudinal study

OBJECTIVE To investigate the diagnostic reliability of mandibular second molar maturation in assessing the mandibular growth peak using a longitudinal design. MATERIALS AND METHODS From the files of the Burlington and Oregon growth studies, 40 subjects (20 from each collection, 20 males and 20 females) with at least seven annual lateral cephalograms taken from 9 to 16 years were included. Mandibular second molar maturation was assessed according to Demirjian et al., and mandibular growth was defined as annual increments of Co-Gn distance. A full diagnostic reliability analysis (including positive likelihood ratio) was performed to establish the diagnostic reliability of dental stages E, F, and (pooled) GH in identifying the imminent mandibular growth peak. RESULTS None of the dental maturation stages reliably identified the mandibular growth peak with greatest overall mean accuracy and positive likelihood ratio of 0.77 (stage F) and 2.7 (stage E), respectively. CONCLUSIONS Use of the mandibular second molar maturation is not recommended for planning treatment requiring identification of the mandibular growth peak.