Jasmina Primožič

Three-dimensional evaluation of early crossbite correction: a longitudinal study

The aim of this longitudinal study was to assess whether correction of unilateral posterior crossbite in the primary dentition results in improvement of facial symmetry and increase of palatal surface area and palatal volume. A group of 60 Caucasian children in the primary dentition, aged 5.3 ± 0.7 years, were collected at baseline. The group consisted of 30 children with a unilateral posterior crossbite with midline deviation of at least 2 mm (CB) and 30 without malocclusion (NCB). The CB group was treated using an acrylic plate expander. The childrens faces and dental casts were scanned using a three-dimensional laser scanning device. Non-parametric tests were used for data analysis to assess differences over the 30 months period of follow-up. The CB children had statistically significantly greater facial asymmetry in the lower part of the face (P < 0.05) and a significantly smaller palatal volume (P < 0.05) than the NCB children at baseline. There were no statistically significant differences between the two groups at 6, 12, 18, and 30 months follow-ups. Treatment of unilateral posterior crossbite in the primary dentition period resulted in an improvement of facial symmetry in the lower part of the face (P < 0.05) and increase of the palatal surface area and palatal volume (P < 0.001). At 30 months, relapse was observed in eight children (26.7 per cent). Treatment of unilateral posterior crossbite in the primary dentition improves facial symmetry and increases the palatal surface area and the palatal volume, though it creates normal conditions for normal occlusal development and skeletal growth.

Treatment Effects of Removable Functional Appliances in Pre-Pubertal and Pubertal Class II Patients: A Systematic Review and Meta-Analysis of Controlled Studies

Background Treatment effects of removable functional appliances in Class II malocclusion patients according to the pre-pubertal or pubertal growth phase has yet to be clarified. Objectives To assess and compare skeletal and dentoalveolar effects of removable functional appliances in Class II malocclusion treatment between pre-pubertal and pubertal patients. Search methods Literature survey using the Medline, SCOPUS, LILACS and SciELO databases, the Cochrane Library from inception to May 31, 2015. A manual search was also performed. Selection criteria Randomised (RCTs) or controlled clinical trials with a matched untreated control group. No restrictions were set regarding the type of removable appliance whenever used alone. Data collection and analysis For the meta-analysis, cephalometric parameters on the supplementary mandibular growth were the main outcomes, with other cephalometric parameters considered as secondary outcomes. Risk of bias in individual and across studies were evaluated along with sensitivity analysis for low quality studies. Mean differences and 95% confidence intervals for annualised changes were computed according to a random model. Differences between pre-pubertal and pubertal patients were assessed by subgroup analyses. GRADE assessment was performed for the main outcomes. Results Twelve articles (but only 3 RCTs) were included accounting for 8 pre-pubertal and 7 pubertal groups. Overall supplementary total mandibular length and mandibular ramus height were 0.95 mm (0.38, 1.51) and 0.00 mm (-0.52, 0.53) for pre-pubertal patients and 2.91 mm (2.04, 3.79) and 2.18 mm (1.51, 2.86) for pubertal patients, respectively. The subgroup difference was significant for both parameters (p<0.001). No maxillary growth restrain or increase in facial divergence was seen in either subgroup. The GRADE assessment was low for the pre-pubertal patients, and generally moderate for the pubertal patients. Conclusions Taking into account the limited quality and heterogeneity of the included studies, functional treatment by removable appliances may be effective in treating Class II malocclusion with clinically relevant skeletal effects if performed during the pubertal growth phase.

Treatment effects of fixed functional appliances alone or in combination with multibracket appliances: A systematic review and meta-analysis.

OBJECTIVE To assess skeletal and dentoalveolar effects of fixed functional appliances, alone or in combination with multibracket appliances (comprehensive treatment), on Class II malocclusion in pubertal and postpubertal patients. MATERIALS AND METHODS Literature survey was conducted using the Medline, SCOPUS, LILACS, and SciELO databases and The Cochrane Library, and through a manual search. The studies retrieved had to have a matched untreated control group. No restrictions were set regarding the type of fixed appliance, treatment length, or to the cephalometric analysis used. Data extraction was mostly predefined at the protocol stage by two authors. Supplementary mandibular elongation was used for the meta-analysis. RESULTS Twelve articles qualified for the final analysis of which eight articles were on pubertal patients and four were on postpubertal patients. Overall supplementary total mandibular elongations as mean (95% confidence interval) were 1.95 mm (1.47 to 2.44) and 2.22 mm (1.63 to 2.82) among pubertal patients and -1.73 mm (-2.60 to -0.86) and 0.44 mm (-0.78 to 1.66) among postpubertal patients, for the functional and comprehensive treatments, respectively. For pubertal subjects, maxillary growth restraint was also reported. Nevertheless, skeletal effects alone would not account for the whole Class II correction even in pubertal subjects with dentoalveolar effects always present. CONCLUSIONS Fixed functional treatment is effective in treating Class II malocclusion with skeletal effects when performed during the pubertal growth phase, very few data are available on postpubertal patients.

Three-dimensional longitudinal evaluation of palatal vault changes in growing subjects

OBJECTIVE To evaluate palatal vault change in children and to assess the reliability of two palatal parameters in assessing growth modifications. SUBJECTS AND METHODS A group of 26 healthy white children aged 5.3 ± 0.3 years (15 boys, 11 girls) were randomly selected. Impressions of the upper dental arches were obtained at baseline and at 12, 18, and 30 months follow-up. Three-dimensional digital images of study casts were obtained using a laser scanning device. Palatal surface area and palatal volume were measured on the digital study casts at each time point. Effect size (ES) coefficients were calculated for both parameters as indices of diagnostic reliability in individual subjects when at least equal to 1.0. RESULTS Significant increases in palatal surface area and volume were seen over the observation period (P < .001). ES coefficients for palatal surface area were greater than those for palatal volume. However, even for the former parameter, only the value taken at 30 months was above the threshold. CONCLUSIONS Growth of the palatal vault was significant during the observation period, which coincides with primary and mixed dentition stages. Palatal surface area appears to be more reliable than palatal volume in assessment of growth modifications in individual subjects.

Three-dimensional assessment of palatal change in a controlled study of unilateral posterior crossbite correction in the primary dentition

The aim of this study was to quantify the palatal change in three groups of children: children with a unilateral posterior crossbite (TCB) who were treated, children with untreated unilateral posterior crossbite (UCB), and children without a crossbite (NCB). Study casts of 60 Caucasian children in the primary dentition (20 TCB, 20 UCB, and 20 NCB), aged 5.4 ± 0.7 years, were collected at baseline (T1) and at 1-year follow-up (T2). Both TCB and UCB groups had unilateral posterior crossbite and midline deviation. The TCB group was treated using a cemented acrylic splint expander in the upper arch. The study casts were scanned using a laser scanner and palatal surface area, palatal volume, and symmetry of the palatal vault were evaluated and compared between the three groups. At T1, the palatal volume of TCB (2698 mm(3)) and UCB (2585 mm(3)) was significantly smaller than that of NCB (3006 mm(3); P < 0.05, analysis of variance test). After treatment, the palatal volume of the TCB group (3087 mm(3)) increased and did not differ from the NCB group (3208 mm(3)), whereas the UCB (2644 mm(3)) had a significantly smaller palatal volume than the NCB or TCB groups (P < 0.05). The increase of palatal volume in the TCB group (389 mm(3)) was significantly greater than in the UCB (59 mm(3)) and NCB (202 mm(3)) groups. The symmetry of the palatal vault was greater than 90 per cent in all three groups at T1 and at T2. Treatment of unilateral posterior crossbite in the primary dentition has a significant effect, particularly on the palatal volume increase.

Associations between the masticatory system and muscle activity of other body districts. A meta-analysis of surface electromyography studies

The aim of this meta-analysis regarding the use of surface electromyography (sEMG) is to assess the scientific evidence for detectable correlations between the masticatory system and muscle activity of the other body districts, particularly those mainly responsible for body posture. A literature survey was performed using the PubMed database, covering the period from January 1966 to April 2011, and choosing medical subject headings. After selection, five articles qualified for the final analysis. One study article was judged to be of medium quality, the remaining four of low quality. No study included a control group or follow-up; in only one study, subjects with impairment of the masticatory system were enrolled. In all studies, detectable correlations between the masticatory systems and muscle activity of the other body districts, or vice versa, were found; however, after a reappraisal of the data provided in these studies, only weak correlations were found, which reached biological, but not clinical relevance. With the limitations that arise from the poor methodological quality of the published study reports discussed here, the conclusion is that a correlation between the masticatory system and muscle activity of the other body districts might be detected through sEMG under experimental conditions; however, this correlation has little clinical relevance. While more investigations with improved levels of scientific evidence are needed, the current evidence does not support clinically relevant correlations between the masticatory system and the muscle activity of other body districts, including those responsible for body posture.

Is gingival crevicular fluid volume sensitive to orthodontic tooth movement? A systematic review of split‐mouth longitudinal studies

To assess the scientific evidence for detectable volume changes of gingival crevicular fluid (GCF) incident to orthodontic tooth movement (OTM). A literature survey of longitudinal split-mouth studies was performed searching PubMed, SCOPUS and the Cochrane Library, with the last access in 15 April 2012. After selection, 13 articles qualified for the final analysis. One study was judged to be of medium/high quality, six were of medium quality and the rest of low quality. Across all studies, there was very little or no statistically significant change in GCF volume incident to OTM. The changes seen were generally ascribed to the clinical or subclinical inflammation consequent to placement of the fixed orthodontic appliance. A reappraisal of the data provided in these studies was performed by comparing the GCF volume from the test (moved) and control (non-moved) teeth, in terms of effects-size (ES) coefficients and variations, as percentages. Generally, the ES coefficients and the variations were below 1.0 and 20%, respectively. Therefore, when using current methods to collect and measure GCF volume, there was no meaningful diagnostic potential for the GCF volume as an index of tissue remodelling incident to OTM. The GCF volume is not a reliable index for tissue remodelling incident to OTM.

Three-dimensional evaluation of facial morphology in children aged 5–6 years with a Class III malocclusion

The aim of this study was to evaluate facial morphology in 25 Class III and 46 non-Class III children aged 5-6 years using three-dimensional (3D) laser imaging; 3D facial images were obtained, two average facial templates were constructed for the non-Class III male and female groups, each individual face was superimposed on the corresponding average template and group comparisons were evaluated (facial height, facial convexity, mandibular position and facial surface morphology). Differences between parameters were evaluated by using an analysis of variance and colour deviation maps. The results showed that Class III children had less mid-face prominence and a concave facial profile when compared to non-Class III children (P = 0.002 and P = 0.018). The position of the pg point in the z-axis just failed to reach statistical significance when comparing the two groups (P = 0.051). A vertical analysis showed no statistical significance between the groups, when evaluating middle (n-sn) and lower (sn-pg) facial height. Coincidence of the Class III faces to normal templates with a tolerance set as 0.5 mm was low (less than 30%). The soft tissue characteristics of a Class III face differ significantly from the non-Class III face in the mid-face region and in the facial profile. A 3D laser imaging method evaluated and identified morphological characteristics of Class III children in deciduous dentition, which could in the future become an important diagnostic tool in small children. The most important clinical advantage of this study is the non-invasiveness of the method.

Influence of sucking habits and breathing pattern on palatal constriction in unilateral posterior crossbite--a controlled study.

The aim of this study was to evaluate the influence of prolonged sucking habits and mouth breathing on palatal vault morphology in a group of subjects with unilateral functional crossbite [crossbite (CB) group] compared with a group of subjects with normal occlusion [non-crossbite (NCB) group]. A sample of 80 Caucasian subjects (51 CB and 29 NCB; aged 5.3 ± 0.8 years) in the deciduous dentition was selected. A questionnaire regarding the subjects sucking habits was answered by the parents. Any sucking habit that lasted more than 24 months was considered as a prolonged sucking habit. The breathing pattern was assessed by an experienced otorinolarygologist and was classified either mainly nose or mouth breathing. Intercanine and intermolar distances and palatal surface area and volume were recorded three dimensionally on study casts. Univariate and multivariate analyses were employed. Posterior CB was negatively correlated with all the dental and palatal parameters (P < 0.01) with the exception of the palatal surface area that did not reach the statistical significance. Only prolonged sucking habits (but not mouth breathing) was a significant risk indicator for unilateral functional CB (P < 0.001). However, the prolonged sucking habits were not significantly correlated with any of the investigated parameter, and mouth breathing was negatively correlated with the intermolar distance only. Therefore, maxillary constriction in unilateral functional CB might not be influenced by the presence or absence of prolonged sucking habits or mouth breathing.

The diagnostic potential of static body-sway recording in orthodontics: a systematic review

Conflicting data have been reported in dentistry regarding the diagnostic potential of monitoring body sway while in a static standing bipedalic position. This systematic review reappraises previously reported effects of mandibular position, asymmetric occlusion, and temporomandibular disorders (TMDs) on body sway to determine whether there is sufficient evidence for such correlations and to define the potential diagnostic applications in orthodontics. A literature survey was performed using the Medline, LILACS, and SciELO databases, and the Cochrane Library, covering the period from January 1980 to December 2011. Twelve articles qualified for the final analysis. All of these studies investigated the effects of mandibular position, two focussed also on asymmetrical occlusion, and three on TMDs. Only two studies were judged to be of medium or medium/high quality, with all of the rest classified as low-quality design; no study included follow-up. According to the conclusions of these reports, four studies saw significant correlations between body sway and mandibular position or TMDs. After a reappraisal of the full data set, generally no clinically relevant correlations were uncovered in the comparisons. While more investigations with improved levels of scientific evidence are needed, according to current evidence, the static monitoring of body sway as a diagnostic aid in orthodontics may not be indicated.