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Dive into the research topics where Jason C. Cole is active.

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Featured researches published by Jason C. Cole.


Health and Quality of Life Outcomes | 2014

Impact of Alzheimer’s Disease on Caregiver Questionnaire: internal consistency, convergent validity, and test-retest reliability of a new measure for assessing caregiver burden

Jason C. Cole; Diane Ito; Yaozhu J Chen; Rebecca Cheng; Jennifer Bolognese; Josephine Li-McLeod

BackgroundThere is a lack of validated instruments to measure the level of burden of Alzheimer’s disease (AD) on caregivers. The Impact of Alzheimer’s Disease on Caregiver Questionnaire (IADCQ) is a 12-item instrument with a seven-day recall period that measures AD caregiver’s burden across emotional, physical, social, financial, sleep, and time aspects. Primary objectives of this study were to evaluate psychometric properties of IADCQ administered on the Web and to determine most appropriate scoring algorithm.MethodsA national sample of 200 unpaid AD caregivers participated in this study by completing the Web-based version of IADCQ and Short Form-12 Health Survey Version 2 (SF-12v2™). The SF-12v2 was used to measure convergent validity of IADCQ scores and to provide an understanding of the overall health-related quality of life of sampled AD caregivers.The IADCQ survey was also completed four weeks later by a randomly selected subgroup of 50 participants to assess test-retest reliability. Confirmatory factor analysis (CFA) was implemented to test the dimensionality of the IADCQ items. Classical item-level and scale-level psychometric analyses were conducted to estimate psychometric characteristics of the instrument. Test-retest reliability was performed to evaluate the instrument’s stability and consistency over time.ResultsVirtually none (2%) of the respondents had either floor or ceiling effects, indicating the IADCQ covers an ideal range of burden. A single-factor model obtained appropriate goodness of fit and provided evidence that a simple sum score of the 12 items of IADCQ can be used to measure AD caregiver’s burden. Scales-level reliability was supported with a coefficient alpha of 0.93 and an intra-class correlation coefficient (for test-retest reliability) of 0.68 (95% CI: 0.50–0.80). Low-moderate negative correlations were observed between the IADCQ and scales of the SF-12v2.ConclusionsThe study findings suggest the IADCQ has appropriate psychometric characteristics as a unidimensional, Web-based measure of AD caregiver burden and is supported by strong model fit statistics from CFA, high degree of item-level reliability, good internal consistency, moderate test-retest reliability, and moderate convergent validity. Additional validation of the IADCQ is warranted to ensure invariance between the paper-based and Web-based administration and to determine an appropriate responder definition.


Alzheimers & Dementia | 2011

Psychometric evaluation of a brief, new instrument for the measurement of caregiver burden: Review of the Impact of Alzheimer's Disease on Caregiver Questionnaire

P.O. Bonnet; Jason C. Cole; Yaozhu Chen; Amit Bodhani; Diane Ito

reliability coefficients; Rasch modelling) and the factor structures of the two measures will be explored and compared (exploratory and confirmatory factor analysis). The relationship between attitudes/beliefs and quality in the pilot sample will also be explored. Conclusions: Families play an important role in the wellbeing and health of older people living in residential settings. A valid and reliable tool to measure the quality of staff-family relationships will enable aged services to assess this potentially important aspect of care. Understanding the association between individual attitudes and beliefs of staff (and families) and the overall quality of relationships may also provide guidance on potential interventions to improve relationships, and by extension, the wellbeing and health of residents.


Journal of The American Academy of Dermatology | 2015

Health care resource use, productivity, and costs among patients with moderate to severe plaque psoriasis in the United States

Caroline P. Schaefer; Joseph C. Cappelleri; Rebecca Cheng; Jason C. Cole; Scott T. Guenthner; Joseph F. Fowler; Sandy Johnson; Carla Mamolo


Value in Health | 2015

Health-Related Quality Of Life (Hrqol) Measures In Autosomal Dominant Polycystic Kidney Disease (Adpkd).

D. Oberdhan; H.B. Krasa; Caroline Schaefer; Jason C. Cole


American Journal of Kidney Diseases | 2017

Development of the Autosomal Dominant Polycystic Kidney Disease Impact Scale: A New Health-Related Quality-of-Life Instrument

Dorothee Oberdhan; Jason C. Cole; Holly B. Krasa; Rebecca Cheng; Frank S. Czerwiec; Ron D. Hays; Arlene B. Chapman; Ronald D. Perrone


Value in Health | 2016

DEVELOPMENT OF A CONCEPTUAL FRAMEWORK FOR ASSESSING DISEASE-SPECIFIC PATIENT-REPORTED OUTCOMES IN NONALCOHOLIC STEATOHEPATITIS

A.C. Palsgrove; S. Hazra; B. Ferguson; R. Cheng; Jason C. Cole


Value in Health | 2013

Psychometric analyses of patient-reported outcome instruments for autosomal dominant polycystic kidney disease

Jason C. Cole; R. Cheng; D. Oberdhan; H.B. Krasa; Ron D. Hays


Archive | 2015

Patient Experience with Pain Related to Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Dorothee Oberdhan; Andrew Palsgrove; Jason C. Cole; Jaime D. Blais; Rebecca Cheng


Archive | 2014

Burden of Autosomal Dominant Polycystic Kidney Disease (Adpkd): Effects on the Daily Lives of Patients and Their Caregivers

Andrew Palsgrove; Lisa M. Guay Woodford; Rebecca Cheng; Dorothee Oberdhan; Jaime D. Blais; Jason C. Cole; Arlene B. Chapman


Value in Health | 2012

PRM110 Planning and Executing Qualitative Research With Adolescents in an Orphan Disease

Jason C. Cole; J. Urwongse; J. Bolognese; R. Cheng

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Ron D. Hays

University of California

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B. Ferguson

Intercept Pharmaceuticals

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S. Hazra

Intercept Pharmaceuticals

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