Jason C. Cole
Pharmaceutical Product Development
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Health and Quality of Life Outcomes | 2014
Jason C. Cole; Diane Ito; Yaozhu J Chen; Rebecca Cheng; Jennifer Bolognese; Josephine Li-McLeod
BackgroundThere is a lack of validated instruments to measure the level of burden of Alzheimer’s disease (AD) on caregivers. The Impact of Alzheimer’s Disease on Caregiver Questionnaire (IADCQ) is a 12-item instrument with a seven-day recall period that measures AD caregiver’s burden across emotional, physical, social, financial, sleep, and time aspects. Primary objectives of this study were to evaluate psychometric properties of IADCQ administered on the Web and to determine most appropriate scoring algorithm.MethodsA national sample of 200 unpaid AD caregivers participated in this study by completing the Web-based version of IADCQ and Short Form-12 Health Survey Version 2 (SF-12v2™). The SF-12v2 was used to measure convergent validity of IADCQ scores and to provide an understanding of the overall health-related quality of life of sampled AD caregivers.The IADCQ survey was also completed four weeks later by a randomly selected subgroup of 50 participants to assess test-retest reliability. Confirmatory factor analysis (CFA) was implemented to test the dimensionality of the IADCQ items. Classical item-level and scale-level psychometric analyses were conducted to estimate psychometric characteristics of the instrument. Test-retest reliability was performed to evaluate the instrument’s stability and consistency over time.ResultsVirtually none (2%) of the respondents had either floor or ceiling effects, indicating the IADCQ covers an ideal range of burden. A single-factor model obtained appropriate goodness of fit and provided evidence that a simple sum score of the 12 items of IADCQ can be used to measure AD caregiver’s burden. Scales-level reliability was supported with a coefficient alpha of 0.93 and an intra-class correlation coefficient (for test-retest reliability) of 0.68 (95% CI: 0.50–0.80). Low-moderate negative correlations were observed between the IADCQ and scales of the SF-12v2.ConclusionsThe study findings suggest the IADCQ has appropriate psychometric characteristics as a unidimensional, Web-based measure of AD caregiver burden and is supported by strong model fit statistics from CFA, high degree of item-level reliability, good internal consistency, moderate test-retest reliability, and moderate convergent validity. Additional validation of the IADCQ is warranted to ensure invariance between the paper-based and Web-based administration and to determine an appropriate responder definition.
Alzheimers & Dementia | 2011
P.O. Bonnet; Jason C. Cole; Yaozhu Chen; Amit Bodhani; Diane Ito
reliability coefficients; Rasch modelling) and the factor structures of the two measures will be explored and compared (exploratory and confirmatory factor analysis). The relationship between attitudes/beliefs and quality in the pilot sample will also be explored. Conclusions: Families play an important role in the wellbeing and health of older people living in residential settings. A valid and reliable tool to measure the quality of staff-family relationships will enable aged services to assess this potentially important aspect of care. Understanding the association between individual attitudes and beliefs of staff (and families) and the overall quality of relationships may also provide guidance on potential interventions to improve relationships, and by extension, the wellbeing and health of residents.
Journal of The American Academy of Dermatology | 2015
Caroline P. Schaefer; Joseph C. Cappelleri; Rebecca Cheng; Jason C. Cole; Scott T. Guenthner; Joseph F. Fowler; Sandy Johnson; Carla Mamolo
Value in Health | 2015
D. Oberdhan; H.B. Krasa; Caroline Schaefer; Jason C. Cole
American Journal of Kidney Diseases | 2017
Dorothee Oberdhan; Jason C. Cole; Holly B. Krasa; Rebecca Cheng; Frank S. Czerwiec; Ron D. Hays; Arlene B. Chapman; Ronald D. Perrone
Value in Health | 2016
A.C. Palsgrove; S. Hazra; B. Ferguson; R. Cheng; Jason C. Cole
Value in Health | 2013
Jason C. Cole; R. Cheng; D. Oberdhan; H.B. Krasa; Ron D. Hays
Archive | 2015
Dorothee Oberdhan; Andrew Palsgrove; Jason C. Cole; Jaime D. Blais; Rebecca Cheng
Archive | 2014
Andrew Palsgrove; Lisa M. Guay Woodford; Rebecca Cheng; Dorothee Oberdhan; Jaime D. Blais; Jason C. Cole; Arlene B. Chapman
Value in Health | 2012
Jason C. Cole; J. Urwongse; J. Bolognese; R. Cheng