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Featured researches published by Javier Lluch.


Brain Research Bulletin | 2007

Cocaine exposure during adolescence affects anxiety in adult mice.

Josefina Estelles; Javier Lluch; Marta Rodríguez-Arias; M.A. Aguilar; José Miñarro

Psychostimulant drugs such as cocaine have profound and long-lasting neurobiological effects, which may affect anxiety or social behaviors. These actions could be greater when cocaine is administered during a developmental period such as adolescence. The present work attempts to further clarify the long-lasting effects of cocaine administration on mice, examining three major variables: age; pattern of drug administration; and housing conditions. Adolescent (postnatal day 26) or early adult mice (postnatal day 46) were exposed to a daily or binge cocaine administration and 15 days later their behavior was evaluated, the mice being housed either in isolation or in groups during this stage. After a period free of drug, the behaviors evaluated were: spontaneous and cocaine-induced motor activity; anxiety, using the elevated plus maze; the social profile, assessed in a social interaction test. Daily cocaine administration increased avoidance and flee in isolated adolescent-treated mice and decreased social contacts in those which were grouped. On the other hand, the binge pattern modified the anxiety of the grouped adolescent-treated mice evidenced by the increase in time spent on the open arms of the plus maze. An increase in spontaneous and cocaine-induced motor activity was shown in animals after a daily pre-treatment. The results are discussed in terms of presenting cocaine-induced behavioral changes within a specific temporal window and depending on the three variables studied.


Journal of Parasitology | 2005

THE COMPONENT HELMINTH COMMUNITY IN SIX SYMPATRIC SPECIES OF ARDEIDAE

Pilar González Navarro; Javier Lluch; Enrique Font

We studied the helminth communities in 6 sympatric species of Ardeidae (Ixobrychus minutus (Linnaeus, 1766), Nycticorax nycticorax (Linnaeus, 1758), Bubulcus ibis (Linnaeus, 1758), Egretta garzetta (Linnaeus, 1766), Ardea cinerea (Linnaeus, 1758), and Ardea purpurea (Linnaeus, 1766)) from “La Albufera de Valencia,” Spain. The survey revealed 13 species of helminth parasites: 5 digeneans, 2 cestodes, and 6 nematodes. The component helminth communities of the Ardeidae examined are depauperate and conform to the pattern typically found in isolationist communities, probably because of their high trophic dependence on a few prey species. Evenness was positively correlated with richness and abundance, but host body weight was not correlated with the number of helminth species or with the total number of helminths. Ardea cinerea is more heavily infected than E. garzetta by Apharyngostrigea cornu, and B. ibis is more heavily infected than both Ardea cinerea and E. garzetta by Desportesius spinulatus. Apharyngostrigea cornu was positively associated with Desmidocercella numidica and D. spinulatus in A. cinerea.


Pharmacology, Biochemistry and Behavior | 2005

Role of dopamine and glutamate receptors in cocaine-induced social effects in isolated and grouped male OF1 mice

Javier Lluch; Marta Rodríguez-Arias; M.A. Aguilar; José Miñarro

Cocaine administration in paired male mice decreases social contacts as well as increases avoidance and flee elements. As dopamine (DA) and glutamate seem to be involved in some of cocaines effects, an attempt was made to assess whether a range of associated receptors influenced the social impacts of this drug of abuse. The NMDA antagonist memantine (10 and 40 mg/kg); the AMPA antagonist CNQX (1 and 20 mg/kg); the DA release inhibitor CGS 10746b (2 and 8 mg/kg): the DA D1 antagonist SCH 23390 (0.05 and 0.5 mg/kg); and the DA D2/D3 antagonist raclopride (0.03 and 0.3 mg/kg) were administered prior to 25 mg/kg of cocaine and behaviour was evaluated during an encounter between an experimental and a standard opponent in a neutral cage for 10 min. Memantine reverts cocaine-induced social withdrawal and the increase in avoidance and flee, CNQX being effective only in these latter actions. On the other hand, SCH 23390 counteracts the social as well as the defensive action of cocaine, raclopride being effective only in blocking the cocaine-induced increase in avoidance and flee behaviours. In conclusion, although both neurotransmitter systems are involved in the effects of cocaine on social behaviour, NMDA and D1DA receptors seem to have an important role.


Journal of Natural History | 2016

Helminth fauna of the invasive American red-eared slider Trachemys scripta in eastern Spain: potential implications for the conservation of native terrapins

Francesc Domènech; Rafael Marquina; Lydia Soler; Luis Valls; Francisco Javier Aznar; Mercedes Fernández; Pilar González Navarro; Javier Lluch

Abstract In this study we report on the helminth fauna of the invasive American red-eared slider Trachemys scripta in five localities from eastern Spain where this species co-occurs with two native, endangered freshwater turtles, i.e. Emys orbicularis and Mauremys leprosa. In total, 46 individuals of T. scripta were analysed for parasites. Adult individuals of three helminth species were found: the monogenean Neopolystoma orbiculare, the digenean Telorchis solivagus and the nematode Serpinema microcephalus. Telorchis solivagus and S. microcephalus are trophically transmitted parasites of native turtles that probably infected T. scripta through shared infected prey. Neopolystoma orbiculare infects T. scripta in its native Nearctic range and probably survived the overseas shipping of hosts due to the combination of a direct life cycle, long lifespan in turtles and crowding conditions that allowed frequent (re)infections. These findings entail potentially significant conservation consequences that deserve further attention. First, there was a successful spill-back of Telorchis solivagus and S. microcephalus to large invasive populations of T. scripta in the study area, which could eventually increase infection levels in native turtles. Second, the possibility of spill-over of N. orbiculare to native turtles should not be underestimated as this phenomenon has recently been reported in France. Given the pathogenic potential of N. orbiculare, its transference to native turtles could be troublesome.


Psychopharmacology | 2009

Social experiences affect reinstatement of cocaine-induced place preference in mice

Bruno Ribeiro Do Couto; M.A. Aguilar; Javier Lluch; Marta Rodríguez-Arias; José Miñarro


Journal of Zoology | 1999

Paracrobeles psammophilus sp. nov. (Nematoda: Cephalobidae) from El Saler, Valencia (Spain)

Pilar González Navarro; Javier Lluch


Gaceta Sanitaria | 2002

HELMINTOS PARÁSITOS DE ARDEIDAE EN VALENCIA (ESPAÑA)

María Luz Nogueserola; Pilar González Navarro; Javier Lluch


Journal of Zoology | 1995

Description of a new species:Dorylaimus parasiticus, a parasite of amphibians in the Iberian Peninsula (Nematoda: Dorylaimida)

Pilar González Navarro; F. Guerrero; Valentín Pérez-Mellado; Javier Lluch


Boletín de la Real Sociedad Española de Historia Natural. Sección biológica | 2017

Primeros datos de la nematofauna edáfica del Campus Universitario de Burjassot (Valencia, España)

Virginia Escribano; Paula Ruiz; Javier Lluch; Pilar González Navarro


La Universitat de València i els seus entorns comarcals: la Ribera del Xúquer, 2016, ISBN 978-84-9133-004-2, págs. 108-111 | 2016

Els amfibis i rèptils de la Ribera del Xúquer

Javier Lluch; José Ignacio Lacomba Andueza; Vicente Sancho; Pilar González Navarro

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Jose Freire

Forest Research Institute

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Javier Milara

Polytechnic University of Valencia

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Max Qian

Forest Research Institute

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Teresa Peiró

National Institutes of Health

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