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Jay Hyok Chang

LG Chem

Publication

Featured researches published by Jay Hyok Chang.

Synlett | 2005

A Stereodivergent Synthesis of Hydroxyethylene Dipeptide Isostere via Highly Diastereoselective Epoxidation

Kyu Woong Lee; Hyeong-wook Choi; Byung Han Lee; Bo Seung Choi; Jay Hyok Chang; Young Keun Kim; Jae Hoon Lee; Taeho Heo; Do Hyun Nam; Hyunik Shin

Epoxidation of δ-amino-β,δ-unsaturated ester with trifluoroperacetic acid afforded its epoxide in a highly diastereo- H selective manner. Subsequent stereodivergent epoxide opening reactions provided synthetic routes towards both the threo and erythro hydroxyethylene peptide isostere.

Journal of Medicinal Chemistry | 1997

Novel fluoroquinolone antibacterial agents containing oxime-substituted (aminomethyl)pyrrolidines : Synthesis and antibacterial activity of 7-(4-(aminomethyl)-3-(methoxyimino)pyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro[1,8]naphthyridine-3-carboxylic acid (LB20304)

Chang Yong Hong; Young Kwan Kim; Jay Hyok Chang; Se Ho Kim; Hoon Choi; Do Hyun Nam; Yong Zu Kim; Jin Hwan Kwak

Archive | 1995

Quinoline carboxylic acid derivatives having 7-(4-amino-methyl-3-oxime) pyrrolidine substituents and processes for their preparation

Jay Hyok Chang; Hoon Choi; Chang Yong Hong; Yi Na Jeong; Mu Yong Kim; Se Ho Kim; Young Kwan Kim; Jin Hwan Kwak; Do Hyun Nam; Jeong In Oh

Archive | 1997

Quinoline carboxylic acid derivatives having 7-(4-amino-methyl-3-oxime)pyrrolidine substituent and processes for preparing thereof

Chang Yong Hong; Young Kwan Kim; Jay Hyok Chang; Se Ho Kim; Hoon Choi; Do Hyun Nam; Jin Hwan Kwak; Yi Na Jeong; Jeong In Oh; Mu Yong Kim

Archive | 1998

Salt of naphthyridine carboxylic acid derivative

Ae Ri Kim; Jin Hwa Lee; Ki Sook Park; Jong Ryoo Choi; Tae Hee Lee; Jay Hyok Chang; Do Hyun Nam; Hoon Choi

Synthesis | 2004

Efficient Activation of Zinc: Application of the Blaise Reaction to an Expedient Synthesis of a Statin Intermediate

Hyunik Shin; Bo Seung Choi; Ki Kon Lee; Hyeong-wook Choi; Jay Hyok Chang; Kyu Woong Lee; Do Hyun Nam; No-Soo Kim

Archive | 1998

7-(4-aminomethyl-3-methyloxyiminopyrrolidin-1-yl)-1- cyclopropyl-6-fluoro-4-oxo-1, 4-dihydro-1, 8-naphthyridine-3-carboxylic acid and the process for the preparation thereof

Chang Yong Hong; Young Kwan Kim; Se Ho Kim; Jay Hyok Chang; Hoon Choi; Do Hyun Nam; Ae Ri Kim; Jin Hwa Lee; Ki Sook Park

Journal of Organic Chemistry | 2007

The decarboxylative Blaise reaction.

Jae Hoon Lee; Bo Seung Choi; Jay Hyok Chang; Hee Bong Lee; Joo-Yong Yoon; Jaeick Lee; Hyunik Shin

Organic Process Research & Development | 2002

Efficient Synthesis of 1-Substituted-5-Hydroxymethylimidazole Derivatives: Clean Oxidative Cleavage of 2-Mercapto Group1

Jay Hyok Chang; Kyu Woong Lee; Do Hyun Nam; Won Sup Kim; Hyunik Shin

Archive | 1999

Process for preparing a protected 4-aminomethyl-pyrrolidi-3-one

Jay Hyok Chang; Won Sup Kim; Tae Hee Lee; Kwang Yul Moon

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