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Jay Wiggins

Bayer HealthCare Pharmaceuticals

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Publication

Featured researches published by Jay Wiggins.

European Journal of Medicinal Chemistry | 1988

Cardiotonic agents 4. Dimaprit analogues as potential cardiovascular selective H2-agonists

Albert H. Owens; Richard Goehring; John W. Lampe; Paul W. Erhardt; William Lumma; Jay Wiggins

Abstract Several derivatives of dimaprit including carbon chain substitution, nitrogen substitution and isothiourea replacements were prepared and tested for inotropic activity in guinea pig papillary muscle preparations. Two derivatives showed moderate positive inotropic effects which were mediated by the H 2 -histaminergic pathway.

Journal of Medicinal Chemistry | 1987

Cardiotonic agents. 1. Novel 8-aryl substituted imidazo[1,2-a]- and -[1,5-a]pyridines and imidazo[1,5-a]pyridinones as potential positive inotropic agents

David D. Davey; Paul W. Erhardt; William C. Lumma; Jay Wiggins; Mark E. Sullivan; David C. Pang; Elinor Cantor

Journal of Medicinal Chemistry | 1991

Novel compounds possessing potent cAMP and cGMP phosphodiesterase inhibitory activity. Synthesis and cardiovascular effects of a series of imidazo[1,2-a]quinoxalinones and imidazo[1,5-a]quinoxalinones and their aza analogues

David D. Davey; Paul W. Erhardt; Elinor Cantor; S. S. Greenberg; W. R. Ingebretsen; Jay Wiggins

Journal of Medicinal Chemistry | 1990

Cardiotonic agents. 6. Histamine analogues as potential cardiovascular selective H2 agonists.

John W. Lampe; Reda G. Hanna; Thomas A. Piscitelli; Yuo Ling Chou; Paul W. Erhardt; William C. Lumma; Stanley Shimen Greenberg; William R. Ingebretsen; Dennis C. Marshall; Jay Wiggins

Journal of Medicinal Chemistry | 1992

Cardiotonic agents. 7. Prodrug derivatives of 4-ethyl-1,3-dihydro- 5-[4-(2-methyl-1H-imidazol-1-yl)benzoyl]-2H-imidazol-2-one.

Kenneth J. Shaw; Paul W. Erhardt; Alfred A. Hagedom; Cynthia A. Pease; William R. Ingebretsen; Jay Wiggins

Drug Development Research | 1988

Tissue specificity of cAMP‐phosphodiesterase inhibitors: Rolipram, amrinone, milrinone, enoximone, piroximone, and imazodan

David C. Pang; Elinor Cantor; Alfred Arthur Hagedorn; Paul W. Erhardt; Jay Wiggins

Academic Radiology | 1998

Safety of Levovist injection in patients undergoing exercise stress echocardiography: A placebo-controlled study

Jay Wiggins; Ginette Jacob; Harold A. Goldstein

Investigative Radiology | 1994

NEW CLINICAL TRIAL EXPERIENCE WITH IOPROMIDE

Harold A. Goldstein; Ginette Jacob; Jay Wiggins

The Journal of Nuclear Medicine | 1991

Gallium-67/Stable Gadolinium Antagonism

Jay Wiggins; Harold A. Goldstein; Hans J. Weinmann

Academic Radiology | 2002

Electrocardiographic effects of diagnostic imaging agents

Jay Wiggins; R Beckmann; H.J Weinmann; R Lehr

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Paul W. Erhardt

Bayer HealthCare Pharmaceuticals

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Elinor Cantor

Bayer HealthCare Pharmaceuticals

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Harold A. Goldstein

Bayer HealthCare Pharmaceuticals

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William C. Lumma

United States Military Academy

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David C. Pang

Bayer HealthCare Pharmaceuticals

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Ginette Jacob

Bayer HealthCare Pharmaceuticals

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John W. Lampe

Bayer HealthCare Pharmaceuticals

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Alfred Arthur Hagedorn

Bayer HealthCare Pharmaceuticals

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David D. Davey

Bayer HealthCare Pharmaceuticals

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Richard Goehring

Bayer HealthCare Pharmaceuticals

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